Peiyan Hua

Multidisciplinary collaborative treatment of a rare case of chronic hemoptysis: diagnostic and therapeutic insights from a 7-year clinical course

Jianxiong Kang, Peiyan Hua

A middle-aged woman who had undergone a right upper and middle lobectomy 7 years earlier presented with recurrent intermittent hemoptysis. Evaluation at our institution revealed that the main right pulmonary artery supplying the remaining lung had previously been transected and ligated. She …

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Influenza vaccination and cardiovascular and respiratory outcomes in high-risk populations: an umbrella review of systematic reviews and meta-analyzes

Chengyan Jin, Y Zhang, Bin Wang, Peiyan Hua

Background: Influenza infection is an important trigger of acute cardiovascular events and respiratory decompensation in vulnerable populations. Although influenza vaccination may reduce cardiopulmonary morbidity and mortality, the overall certainty and methodological reliability of the evidence remain unclear. Objective: To synthesize and critically …

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Association between multimarkers of metabolic malnutrition and inflammation and risk of chronic obstructive pulmonary disease and lung function: a prospective cohort study of UK biobank

Chengyan Jin, Peiyan Hua, Chunguang Wang, Bin Wang et autres

BACKGROUND: Chronic obstructive pulmonary disease (COPD) pathogenesis involves the cross-links between inflammation, oxidative stress, and metabolic dysregulation leading to irreversible airflow limitation. The metabolic vulnerability index (MVX) integrates inflammation and metabolic malnutrition related metabolic biomarkers that may reflect these underlying mechanisms. This …

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A study on the prediction of targeted therapy efficacy in advanced lung adenocarcinoma patients with EGFR mutations using CT-based delta-radiomics model

Zhishen Wu, Peiyan Hua, Xiuying Chen, Jie Lei et autres

Objective: This study aimed to evaluate the predictive performance of integrated clinical and CT-based radiomic models for assessing targeted therapy efficacy in advanced lung adenocarcinoma patients with EGFR (epidermal growth factor receptor) mutations. Materials and methods: = 32) cohorts at a 7:3 …

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Hemoptysis in a Complex Case: Unraveling Underlying Factors

Jianxiong Kang, Mu Wang, Peiyan Hua, Bin Wang

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Super-resolution imaging reveals the role of DDR1 cluster in NSCLC proliferation

Baofeng Li, Xiao Qi, Meng Li, Peiyan Hua et autres

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Robust anti-tumor immunity through the integration of targeted lipid nanoparticle-based mRNA nanovaccines with PD-1/PD-L1 blockade

Chengyan Jin, Yan Zhang, Baofeng Li, Tianci Gao et autres

Tumor mRNA vaccines present a personalized approach in cancer immunotherapy, encoding distinct tumor antigens to evoke robust immune responses and offering the potential against emerging tumor variants. Despite this, the clinical advancement of tumor mRNA vaccines has been hampered by their limited …

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Exosomes: efficient macrophage-related immunomodulators in chronic lung diseases

Jianxiong Kang, Peiyan Hua, Xiaojing Wu, Bin Wang

Macrophages, the predominant immune cells in the lungs, play a pivotal role in maintaining the delicate balance of the pulmonary immune microenvironment. However, in chronic inflammatory lung diseases and lung cancer, macrophage phenotypes undergo distinct transitions, with M1-predominant macrophages promoting inflammatory damage …

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Integrative Analysis of Prognostic Value and Immune Infiltration of ELOVL Gene Family in Lung Adenocarcinoma

Jindong Li, Yan Zhang, Chengyan Jin, Bin Wang et autres

Abstract Introduction: Lung adenocarcinoma (LUAD) has drawn attention recently because of its poor prognosis, limited responsiveness to treatment, and lack of trustworthy markers for predicting its development or its response to treatment. It has been established that the pathophysiology and development of …

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A rare case report: co-occurrence of two types of lung cancer with hamartoma and pulmonary tuberculosis

Jianxiong Kang, Mu Wang, Peiyan Hua, Bin Wang

With the widespread use of low-dose chest Computed Tomography (CT), lung nodules are being increasingly detected. Common pulmonary conditions such as lung adenocarcinoma, lung squamous cell carcinoma, and tuberculosis are typically diagnosable through imaging examinations. Nevertheless, when multiple types of lung cancer …

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Concordance of ctDNA and tissue mutations in NSCLC: A meta-analysis

Chengyuan Yu, Yitong Han, Mu Wang, Peiyan Hua et autres

Systematic evaluation of the consistency between circulating tumor DNA (ctDNA) in plasma and tumor tissue samples in mutations in non-small cell lung cancer (NSCLC) patients. To collect publicly published literature from numerous important international medical databases through computer retrieval. To compare the …

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Retraction Note: Inhibited MicroRNA-301 Restrains Angiogenesis and Cell Growth in Esophageal Squamous Cell Carcinoma by Elevating PTEN

Bin Wang, Peiyan Hua, Ruimin Wang, Jindong Li et autres

Unlikely appearance of the data presented in the flow cytometry histograms in Fig.

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