Tong‐Fei Li

A one-pot aptamer-initiated triple-cascade amplification strategy for ultrasensitive detection and in situ imaging of platelet-derived growth factor-BB

Tong‐Fei Li, Yi-Xun Gao, Chunguang Yang, Feng Yong-Hui et autres

Microbiota‐Driven Bacterial Therapies for Colorectal Cancer: Mechanistic Insights, Delivery Engineering, and Clinical Translation

Zhuo Xiang, Tong‐Fei Li, W.Z. Wu, Min Ge et autres

ABSTRACT The gut microbiota plays a critical role in colorectal cancer (CRC) initiation, progression, metastasis, and therapeutic response through complex interactions among microbial communities, metabolites, and the tumor immune microenvironment. Increasing evidence reveals that CRC‐associated bacteria regulate tumor development by inducing genomic …

cn, hk (code pays fourni par la source)

Teniposide facilitates macrophage phagocytosis by targeting the CD47-SIRPα axis and the candidate protein TRIM54 in lung cancer

Ning Han, Long Nie, Liu‐Gen Li, Xing‐Chun Peng et autres

cn (code pays fourni par la source)

Chlorin e6-mediated sublethal photodynamic therapy modulates biomarkers in a murine lung cancer–derived in vitro cancer-associated fibroblast model

Shuntianci Zhang, Jun Shi, Fan Leng, Liu‐Gen Li et autres

cn (code pays fourni par la source)

Nano-hydrogel-based delivery system for dihydroartemisinin to enhance cuproptosis and synergize with anti-PD-1 therapy in triple-negative breast cancer

Qiaoli Yi, Fada Xia, Tong‐Fei Li, Jiayu Wang et autres

As an aggressive subtype of breast cancer, triple-negative breast cancer (TNBC) displays limited therapeutic options and poor clinical prognosis. Thus, there is an urgent need for developing more effective treatment strategies to optimize the clinical management of TNBC. Dihydroartemisinin (DHA), one kind …

cn (code pays fourni par la source)

Cepharanthine-mediated PD-L1 autophagic degradation via regulation of TSPO and RILP boosts anti-lung cancer chemo-immunotherapy efficacy

Yu-Jie Gao, Si-Yuan Chen, Liu‐Gen Li, Xiao-Feng Bai et autres

cn (code pays fourni par la source)

Hollow MnFe Bimetallic Nanoboxes for Photo/Chemodynamic Therapy via Amplification of Endoplasmic Reticulum Stress

J Zhou, Anqi Chen, Liugen Li, Hu Chen et autres

Endoplasmic reticulum stress (ERS) triggered by reactive oxygen species (ROS) buildup can lead to immunogenic cell death (ICD), thereby improving the efficacy of cancer therapy. However, the therapeutic efficacy of this strategy remains limited by the insufficient ROS generation rates of nanomedicines …

cn (code pays fourni par la source)

Dihydroartemisinin-Loaded ZIF-8 Nanoparticles Elicit Chemo-Immunotherapy against Malignant Pleural Effusion via Inhibition of OCT4/M-CSF Signaling Pathway

Hui You, Liu‐Gen Li, Chuan-Yong Xiao, Xiao Wang et autres

Malignant pleural effusion (MPE) is the most common complication of lung cancer with an extremely high lethality, for which no effective chemotherapeutic agent is available. Activation of local antitumor immunity of MPE while selectively destroying the malignant cells represents an effective strategy …

cn (code pays fourni par la source)

Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets

Xiang-Yi Zhao, Sai Lei, Min Yan, Xuan Jade Jiang et autres

cn (code pays fourni par la source)

OTUD3-mediated deubiquitination licenses TEX264 to orchestrate ER-phagy for KDM5B degradation in teniposide lung cancer therapy

Ning Han, Xin-Ran Yu, Liu‐Gen Li, Jun Hu et autres

cn, us (code pays fourni par la source)

Deciphering Copper Homeostasis and Cuproptosis: Biological Mechanisms, Disease Connections, and Cutting-Edge Copper-Based Nanomedicine

Shu-Xin Zhang, Lei Li, Lu-jin Wang, Nannan Chen et autres

Copper (Cu), as an essential trace element, participates in various physiological processes through strict homeostatic regulation. Abnormal intracellular copper accumulation can cause multiple forms of copper-dependent cell death (including apoptosis, autophagy, ferroptosis, and the recently identified cuproptosis) and disrupt cellular functions, which …

cn, us (code pays fourni par la source)

Functional doxorubicin and iron ions dual-loaded carboxymethyl chitin-based microspheres for hepatocellular carcinoma therapy via embolization, ferroptosis, and autophagy-mediated HIF-1α inhibition

Fan Leng, Sai Lei, Si-Han Zhang, Cui Hu et autres

cn (code pays fourni par la source)