Jill‐Léa Ramassamy

High prevalence of HTLV-1 among blood donors in southeastern Gabon (Central Africa): a major challenge for transfusion safety in a semi-rural area

Hanneke Moussonda-Mouélé, Jill‐Léa Ramassamy, Eldridge Fedricksen Oloumbou, Antony Idam Mamimandjiami et autres

ABSTRACT Sub-Saharan Africa is an endemic region for human T-lymphotropic virus type 1 (HTLV-1). While high prevalence rates have been reported across Gabon, systematic screening of blood donors has not yet been implemented at the national level. A cross-sectional study was conducted …

Gabon, fr (code pays fourni par la source)

Filovirus Surveillance in Communities Bordering Equatorial Guinea, Marburg Outbreak, Cameroon, 2023

Jill‐Léa Ramassamy, Flaubert Auguste Mba Djondzo, Innocent Ndong Bass, Ginette Edoul et autres

After the 2023 Equatorial Guinea Marburg virus (MARV) outbreak, surveillance of 181 persons in southern Cameroon detected MARV antibodies in 3 persons and Ebola virus antibodies in 7. Testing of 289 captured bats, including 158 Rousettus aegyptiacus bats, did not detect MARV …

fr (code pays fourni par la source)

Quantifying how multiple transmission routes contribute to the spread of HTLV-1 in different endemic foci: a mathematical modelling study

Noé Ochida, Jill‐Léa Ramassamy, Délia Doreen Djuicy, Sabine Plancoulaine et autres

BACKGROUND: Human T-lymphotropic virus 1 (HTLV-1) infection is estimated to affect at least 5-10 million people globally and can cause adult T-cell leukaemia/lymphoma. The global distribution of HTLV-1 is characterised by endemic foci (prevalence confined to specific populations) in Japan, Africa, the …

fr, Cameroun, Gabon, jp, au (code pays fourni par la source)

HTLV-1 genetic diversity of 52 complete sequences from 14 African countries reveals novel variants and a lack of typical P12/P8 and P30 accessory proteins in HTLV-1b, d, and f genotypes

Olivier Cassar, Délia Doreen Djuicy, Giovanni Begliomini, Jill‐Léa Ramassamy et autres

Central Africa is the largest region of human T-cell Leukaemia virus (HTLV-1) endemicity with several million people estimated to be infected. Based on the study of the LTR region, it is also the region with the highest HTLV-1 diversity, with the presence …

HTLV-1 Genetic Diversity of 52 Complete Sequences from 14 African Countries Reveals Novel Variants and Lack of Typical P12/P8 and P30 Accessory Proteins in HTLV-1b, d and f Genotypes.

Olivier Cassar, Délia Doreen Djuicy, Giovanni Begliomini, Jill‐Léa Ramassamy et autres

Central Africa is the largest region of human T-cell Leukemia virus (HTLV-1) endemicity with several million people estimated to be infected. Based on the study of the LTR region, it is also the region with the highest HTLV-1 diversity, with presence of …

HTLV-1 genetic diversity of 52 complete sequences from 14 African countries reveals novel variants and a lack of typical P12/P8 and P30 accessory proteins in HTLV-1b, d, and f genotypes

Olivier Cassar, Délia Doreen Djuicy, Giovanni Begliomini, Jill‐Léa Ramassamy et autres

Central Africa is the largest region of human T-cell Leukemia virus (HTLV-1) endemicity with several million people estimated to be infected. Based on the study of the LTR region, it is also the region with the highest HTLV-1 diversity, with presence of …

fr, Cameroun, Gabon, gb (code pays fourni par la source)

HTLV-1 genetic diversity of 52 complete sequences from 14 African countries reveals novel variants and a lack of typical P12/P8 and P30 accessory proteins in HTLV-1b, d, and f genotypes

Olivier Cassar, Délia Doreen Djuicy, Giovanni Begliomini, Jill‐Léa Ramassamy et autres

Central Africa is the largest region of human T-cell Leukaemia virus (HTLV-1) endemicity with several million people estimated to be infected. Based on the study of the LTR region, it is also the region with the highest HTLV-1 diversity, with the presence …

High potential for zoonotic pathogen emergence through wildlife exposure in East Cameroon

Jill‐Léa Ramassamy, Chanceline Bilounga Ndongo, Patrick Nnuka, Richard Njouom et autres

Zoonotic disease emergence is a major concern within the One Health framework, driven by close human–wildlife interactions. We surveyed 3400 individuals in East Cameroon, revealing widespread bushmeat consumption and frequent animal contacts with rodents, non-human primates and bats. Women were highly exposed, …

fr, Cameroun, Burundi, Maroc (code pays fourni par la source)

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV ‐1 genetic diversity in the two main ethnic populations

Jill‐Léa Ramassamy, Patricia Tortevoye, Balthazar Ntab, Gabriel Carles et autres

Adult T-cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T-cell leukemia virus type 1 (HTLV-1). French Guiana, located in northeastern South America, is a region of high HTLV-1 endemicity with a multiethnic population. We conducted a comprehensive 30-year …

fr, gf, re, gp (code pays fourni par la source)

High genetic diversity of mpox virus (MPXV) in three different rodent species in the Democratic Republic of the Congo (DRC)

Meris Matondo, Pascal Baelo, Audrey Lacroix, Grace Odia Kadima et autres

Altough zoonotic spillover events continue to drive human mpox outbreaks in the Democratic Republic of the Congo (DRC), the wildlife reservoir of mpox virus (MPXV) remains unkown. To address this gap, we screened samples from 2,701 wild mammals, mainly rodents (59.7%), bats …

République démocratique du Congo, be (code pays fourni par la source)

High Seroreactivities to Orthoebolaviruses in Rural Cameroon: A Case-Control Study on Nonhuman Primate Bites and a Cross-sectional Survey in Rural Populations

Jill‐Léa Ramassamy, Ahidjo Ayouba, Guillaume Thaurignac, Chanceline Bilounga Ndongo et autres

BACKGROUND: Ebola (EBOV) and Sudan (SUDV) orthoebolaviruses are responsible for lethal hemorrhagic fever outbreaks in humans in Central and West Africa, and in apes that can be at the source of human outbreaks for EBOV. METHODS: To assess the risk of exposure …

fr, Maroc, Cameroun, Burundi, ru (code pays fourni par la source)

Small mammals at the edge of deforestation in Cambodia: Transient community dynamics and potential pathways to pathogen emergence

Mathieu Pruvot, Sokha Chea, Vibol Hul, Samat In et autres

Conversion of forest to agricultural land results in rapid and profound changes in ecosystems and biodiversity loss and increases the risk of pathogen emergence. However, insights into the underlying ecological processes linking deforestation and pathogen spillover are required to anticipate and mitigate …

us, ca, kh, au (code pays fourni par la source)