Chao Zhu

Modelling and assessing eutrophication and antibiotic risks in a lake system under large‑scale water diversion

Yihan Chen, Shuanggang Hu, Yi Yang, Kangping Cui et autres

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Twenty‐Four Cases of Severe ANCA ‐Associated Vasculitis Treated With Plasma Exchange: A Clinical Analysis and Long‐Term Follow‐Up

Z. CHEN, Wenhao Li, Zhiyong Guo, Chao Zhu

Advances in the understanding of anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) pathophysiology have expanded the application of plasma exchange (PE) in severe cases; however, robust evidence on its efficacy, safety, and long-term outcomes remains scarce. This retrospective study evaluated the short-term efficacy, …

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Novel Transcription Factor TrTRC-1 Controls Amino Acid Biosynthesis to Regulate Cellulase and Xylanase Production in Trichoderma reesei

Guanchen Liu, Quan Zhang, Chao Zhu, Huipeng Gao et autres

The fungus Trichoderma reesei is widely employed for industrial enzyme production. However, the mechanisms coordinating enzyme production with amino acid biosynthesis and metabolism remain incompletely understood. Here, we characterized a novel C 2 H 2 zinc finger transcription factor, TrTRC-1, in T. …

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Lymph Node Metastasis-Associated Spatiotemporal Mapping of the TFF3-Linked Niche in Breast Cancer: Integrating Radiogenomic Signatures with Immune-Ecosystem Remodeling

Chao Zhu, Haoxuan Huang, Yuchen Cao, Gengxi Cai et autres

Primary breast cancer (PBC) with axillary lymph node metastasis (ALNM+) is associated with distinct clinical outcomes, including reduced survival (The Cancer Genome Atlas/Foshan cohorts, P < 0.05) and an attenuated response to anti-programmed cell death protein 1 antibody/anti-programmed death-ligand 1 antibody (anti-PD-1/anti-PD-L1) …

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Strain‐Induced Robust Skyrmion Lattice at Room Temperature in van der Waals Ferromagnet

Xinyi Zhou, Iftikhar Ahmed Malik, Ruihuan Duan, Hanqing Shi et autres

Abstract Manipulating topological magnetic orders of 2D magnets by strain, once achieved, offers enormous potential for future low‐power flexible spintronic applications. In this work, by placing Fe 3 GaTe 2 (FGaT), a room‐temperature 2D ferromagnet, on flexible substrate, a field‐free and robust …

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Contrastive cognition into the occurrence, source identification and risk assessment of antibiotics in various drinking water sources

Min Zhang, Chao Zhu, Ruifang Yang, Gaofang Yin et autres

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Harnessing quorum sensing to enhance butanol production and tolerance in Clostridium acetobutylicum

Zixuan Wang, Chao Zhu, Jingfang Chen, Cuihuan Sun et autres

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Elucidating the Biosynthesis and Function of an Autoinducing Peptide in Clostridium acetobutylicum

Chao Zhu, Zixuan Wang, Xiaoyu Zhou, Youduo Wu et autres

Abstract Clostridia produce autoinducing peptides (AIPs) regulated by the accessory gene regulator (Agr) quorum sensing system, playing a critical role in intercellular communication. However, the biosynthetic pathway and regulatory functions of clostridial AIPs remain inadequately characterized. In this study, we employed chemical …

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Elucidating the Biosynthesis and Function of an Autoinducing Peptide in Clostridium acetobutylicum

Chao Zhu, Zixuan Wang, Xiaoyu Zhou, Youduo Wu et autres

Clostridia produce autoinducing peptides (AIPs) regulated by the accessory gene regulator (Agr) quorum sensing system, playing a critical role in intercellular communication. However, the biosynthetic pathway and regulatory functions of clostridial AIPs remain inadequately characterized. In this study, we employed chemical quantification, …

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Adaptive Transformer Modelling of Density Function for Nonparametric Survival Analysis

Xin Zhang, Deval Mehta, Yanan Hu, Chao Zhu et autres

Survival analysis holds a crucial role across diverse disciplines, such as economics, engineering and healthcare. It empowers researchers to analyze both time-invariant and time-varying data, encompassing phenomena like customer churn, material degradation and various medical outcomes. Given the complexity and heterogeneity of …

Comprehensive insights into the occurrence characteristics of dissolved organic matter and its indication for heavy metals in drinking water sources

Chao Zhu, Ke Wu, Dongmei Xu, Xiaofei Tang et autres

Dissolved organic matter (DOM) plays a crucial role in various aquatic environments, while comprehensive insights into DOM and its relations with heavy metals in drinking water sources are still lacking. Here, we choose the drinking water sources of Anhui province (China) as …

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Single-cell and whole-transcriptome sequencing of lymph node metastasis-related gene signature: A large-scale pan-cancer cohort, machine learning and experimental study: [RETRACTED]

Jianguo Lai, Yan He, Xiaoqing Cai, Yuchen Cao et autres

Background: Lymph node metastasis (LNM) is an independent prognostic factor in numerous types of cancer. Therefore, a LNM-related gene-based nomogram may precisely predict survival and drug sensitivity, and reveal the mechanism underlying LNM. Materials and Methods: Gene sequencing profiles of pan-cancer data …

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