Marwa A. Fouad

Novel iminophosphorane derivatives as dual carbonic anhydrase and COX-2 inhibitors with potent anti-breast cancer activity

Hala El-Shanawany, Soher S. Maigali, Naglaa F. El‐Sayed, Mansoura A. Abd-El-Maksoud et autres

pl, Égypte, iq (code pays fourni par la source)

Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation

Sammar Fathy Elhabal, Ahmed Mohsen Elsaid Hamdan, Mai S. Shoela, Suzan Awad AbdelGhany Morsy et autres

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that causes progressive joint damage and systemic effects. Naringin (NRG), a citrus-derived flavonoid with potent anti-inflammatory and antioxidant activities, is hindered by poor solubility and low bioavailability in clinical applications. NRG was encapsulated …

Égypte, sa (code pays fourni par la source)

Cytotoxic activity of biogenic zinc oxide nanoparticles mediated by cycloartane saponins from Passiflora edulis: Experimental validation and computational modeling

Abeer H. Elmaidomy, Alshymaa Abdel-Rahman Gomaa, Ihsan Alrubaie, Marwa A. Fouad et autres

Égypte, iq, sa (code pays fourni par la source)

Next-Generation Minimally Invasive Anti-Aging Therapy: Incorporation of Resveratrol-Nicotinamide Cerosomes into PLGA Microneedles for Enhanced Skin Permeation

Sammar Fathy Elhabal, Mai S. Shoela, Fatma E. Hassan, Suzan Awad AbdelGhany Morsy et autres

Background/Objectives: Skin aging and wrinkle formation are primarily driven by ultraviolet (UV)-induced oxidative stress and inflammation. Resveratrol (RSV) and nicotinamide (NCT) possess potent anti-aging properties but suffer from poor skin penetration. This study aimed to develop an advanced transdermal delivery system incorporating …

Égypte, sa (code pays fourni par la source)

Design and synthesis of new phosphazine and triazole derivatives for treatment of Alzheimer's disease: modulating ROS/JNK and Wnt/β-catenin signaling pathways

Rania S. Salah, Naglaa F. El‐Sayed, Marwa El-Hussieny, Shaimaa T. Mansour et autres

production, and reduced reactive oxygen species (ROS) generation. Furthermore, both compounds inhibited the activation of JNK and Puma, promoted Beclin-1 expression, and activated Wnt/β-catenin signaling, as evidenced by increased expression levels of Wnt7a, β-catenin, LRP6, and FZD4, alongside decreased expression levels of …

Égypte, pl, fr (code pays fourni par la source)

Harnessing Dual Power: Genistein-Loaded Pumpkisomes in Pullulan Microneedles for Potent Antioxidant and Anticancer Therapy Against Ehrlich Ascites Carcinoma and Breast Cancer Cells

Sammar Fathy Elhabal, Mai S. Shoela, Mohamed Fathi Mohamed Elrefai, F. M. Hassan et autres

Background/Objectives: Breast cancer remains one of the leading causes of cancer-related mortality. Still, limited drug delivery systems for genistein, a powerful natural anticancer agent, draw significant attention. We aimed to develop a co-therapeutic/synergistic dual-compartment system; genistein-loaded pumpkisome nanovesicles (GNS-PKs) incorporated into pullulan …

Égypte, sa (code pays fourni par la source)

Éruption dermatomyosite-like induite par l’hydroxyurée

Luís Inês, T. Ranim, I. Chaabane, Marwa A. Fouad et autres

Tunisie, ch (code pays fourni par la source)

Recent advances in saponin-lipase-microbiota triad effect on obesity management, a comprehensive review

Mohamed Saleh Abdelfattah, Marwa A. Fouad, Sherweit Hamed El-Ahmady, Mohamed Ali Farag

Égypte (code pays fourni par la source)

Corrélation in vitro/in vivo et bénéfice d’un traitement antifongique combiné dans les teignes à Microsporum canis

Marwa A. Fouad, N. Ben Salah, Sameh Belgacem, Dhouha Daghari et autres

Tunisie (code pays fourni par la source)

Design and development of potent roflumilast analogues targeting PDE-4B: selectivity and pharmacokinetic insights

Ahmed M. Moussa, Heba Abdelrasheed Allam, Ahmed Ali Al-Karmalawy, Radwan A. Alnajjar et autres

Égypte, iq, Libye (code pays fourni par la source)

Quinolone as a Privileged Scaffold: A Brief Overview on Early Classical and Recent Advanced Synthetic Pathways, Innovative Neuroprotective Potential, and Structure‐Activity Relationships

Esraa Abdo Moustafa, Nahed N. E. El-Sayed, Marwa A. Fouad, Ahmed Mahmoud El Kerdawy et autres

Neurodegenerative disorders represent the second largest group of diseases worldwide. 2(1H)-quinolone and its structural congener, 4(1H)-quinolone have recently become significant topics in the field of drug design and development of modulators of neurotransmitter systems and neuroprotective agents to tackle neurodegenerative disorders. In …

Égypte, gb (code pays fourni par la source)

Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies

Walaa H. El-Maadawy, Ehab O. A. Hafiz, Samer A. Tadros, Sally Atef Fahim et autres

Benign prostatic hyperplasia (BPH) is a prevalent progressive age-related disorder in men, yet its etiopathophysiology remains poorly understood. Current treatments like finasteride (Fin) have limited long-term efficacy, necessitating alternative therapies. Hydroxychloroquine (HCQ), a safe antimalarial agent, possesses anti-inflammatory, immunomodulatory, and antiproliferative activities, …

Égypte (code pays fourni par la source)