A Konno

Relationships between lung function, allergy, and wheezing in urban children

A Konno, Vinay P. Goswamy, Agustin Calatroni, Peter J. Gergen et autres

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Feasibility of Modified Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy: A Retrospective Analysis

A Konno, Yuji Matsumoto, Tatsuya Imabayashi, Midori Tanaka et autres

BACKGROUND: Endobronchial ultrasound (EBUS)-guided intranodal forceps biopsy (IFB), a diagnostic bronchoscopic technique for intrathoracic lymphadenopathy, is performed following EBUS-guided transbronchial needle aspiration (TBNA). The current EBUS-IFB technique is complex and provides small sample volumes. We modified this technique to allow the use …

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Diaphragmatic hernia during treatment of lung cancer harboring an EGFR mutation

A Konno, Osamu Narumoto, Shota Yamamoto, Miho Yamaguchi et autres

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are a first-line treatment for patients with nonsmall-cell lung cancer harboring EGFR mutations. We report a 65-year-old Japanese woman with nonsmall-cell lung cancer taking an EGFR-TKI who visited the emergency department with acute …

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O3-4 Etoposide, doxorubicin, and cisplatin with mitotane in metastatic adrenocortical carcinoma in the National Cancer Center

Masaki Uchihara, Maki Tanioka, Yuki Kojima, A Konno et autres

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Alectinib for Miliary Lung Metastasis in ALK-Positive Lung Adenocarcinoma

Hironori Satoh, Yusuke Okuma, Jumpei Kashima, A Konno et autres

Background: Miliary pulmonary metastasis characterized by tiny nodules is a rare metastatic pattern in advanced non-small cell lung cancer (NSCLC) and is usually seen in patients harboring an EGFR mutation, and amylase-producing lung cancer is highly uncommon and rarely reported in NSCLC …

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Migrated coil expectorated 12 years after embolization of pulmonary arteriovenous malformation, due probably to abscess formation around the coil

A Konno, Shota Yamamoto, Junko Suzuki, Takeshi Fukami et autres

Pulmonary arteriovenous malformations (PAVMs) are rare vascular structures providing direct capillary-free communications between pulmonary arteries and veins. Embolotherapy is indicated as a front-line therapy. We report an unusual long-term complication of coil embolization for a 44-year-old woman with hereditary hemorrhagic telangiectasia (HHT) …

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SUMO post-translational modification is required for the chromosome circularization in fission yeast

Sae Fujita, A Konno, Kei Kawakami, Katsunori Tanaka

The benefit of stool mycobacterial examination to diagnose pulmonary tuberculosis for adult and elderly patients

A Konno, Osamu Narumoto, Hirotoshi Matsui, Keita Takeda et autres

Background In patients with suspected pulmonary tuberculosis, who have difficulty in expectorating sputum, alternative specimens by invasive procedures, gastric aspirate or sputum suction, are not always available in the feeble elderly. Several studies report the benefit of stool test for pediatric or …

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Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs

Emma Louise Meredith, Ambika Kumar, A Konno, Joanna Szular et autres

Summary Quinone‐based compounds have been exploited to treat infectious diseases and cancer, with such chemicals often functioning as inhibitors of key metabolic pathways or as prodrugs. Here, we screened an aziridinyl 1,4‐benzoquinone (ABQ) library against the causative agents of trypanosomiasis, and cutaneous …

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Acquired hemophilia A associated with myasthenia gravis and Isaacs' syndrome

Takahiro Takeda, A Konno, Toshio Kazama, Miki T. SUZUKI et autres

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Usability Assessment of Laboratory Data Printed on the Prescription for Outpatients

Toshiaki Igarashi, Takaaki Kodawara, A Konno, Yukio Kamitani et autres

We disclosed laboratory data on the prescription for outpatients from April 2011. In order to evaluate the usefulness of this approach, we regularly have meetings with pharmacists of plural outpatient pharmacies. We analyzed the data that was accumulated to investigate the usage …

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Link between inflammation and aquaporin‐5 distribution in submandibular gland in sjögren’s syndrome?

MS Soyfoo, A Konno, Nargis Bolaky, J.S. Oak et autres

OBJECTIVE: To determine whether a link exists between inflammation and aquaporin-5 distribution in submandibular glands from three animal models for Sjögren's syndrome: IQI/JIC, r1ΔT/r2n and non-obese diabetic mice. METHODS: Mice of different ages were used. Inflammatory infiltrates were quantified using the focus …

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