Kuan‐Hung Liu

Enhanced label-free SERS detection of uremic toxins in clinical spent dialysate

Han Lee, Jiunn-Der Liao, Yi-Shan Guo, Chung‐Yu Wang et autres

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Prognostic Value of Remote Monitoring Alarms for Technique Failure in Automated Peritoneal Dialysis

Kuan-Chiao Huang, Jo-Yen Chao, Kuan‐Hung Liu, Wei-Ren Lin et autres

INTRODUCTION: While remote patient monitoring (RPM) is associated with decreased hospitalization and technique failure in automated peritoneal dialysis (APD), the prognostic utility of individual alarm patterns remains unclear. METHODS: We performed a retrospective, single-center cohort study of adult APD patients managed with …

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SGLT2 inhibitors, GLP-1 RAs, and DPP4 inhibitors and the risk of hypomagnesemia in type 2 diabetes: A target trial emulation

Shih‐Chieh Shao, Daniel Hsiang‐Te Tsai, Albert Tzu-Ming Chuang, Kuan‐Hung Liu et autres

BACKGROUND: Recent studies have suggested potential effects on magnesium homeostasis associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RA). We sought to determine whether these effects lead to a reduced risk of hypomagnesemia among adults with type …

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Application of ES-DMA-CPC for Comprehensive Molecular Profiling in Hemodialysis: A Focus on β2-Microglobulin

Alice Chinghsuan Chang, Kuan‐Hung Liu, Pingfu Fu, Bin Hsu et autres

Accumulation of middle- and large-sized uremic toxins has been associated with frailty and mortality in hemodialysis patients. In clinical practice, immunological methods are used for the quantification of those toxins; however, the requirement for expensive antibodies and chemicals limits their clinical application. …

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Integrating machine learning and metabolomics to uncover new biomarkers for predicting pesticide exposure among patients with kidney function decline

Junne‐Ming Sung, Wan-Ru Wang, Chiau-Jun Chu, Yen‐Ping Lin et autres

Although pesticide application is indispensable for agricultural productivity, improper use can pose significant health risks, particularly for vulnerable populations. This study investigated the effects of pesticide exposure on metabolic pathways and disease progression among patients with chronic kidney disease (CKD). This longitudinal …

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Automatic Residual Feed Recognition and Cleaning System

Shu‐Min Tsai, Ming‐Lin Chuang, Chun-Wei Hsu, Kuan‐Hung Liu et autres

This study presents an automated system for detecting and removing residual feed in aquariums using YOLOv5 and an Arduino-controlled mechanism. The system captures real-time images, detects feed residues, and activates a solenoid valve and water pump for removal. Tested in a 45cm …

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Risk of intradialytic hypotension among different antihypertensives in haemodialysis patients

Tzu‐Ying Chen, Miyuki Hsing‐Chun Hsieh, Fang-Yi Su, Chiachi Bonnie Lee et autres

Background: Evaluating the impact of antihypertensives on intradialytic hypotension (IDH) risk is crucial, given their frequent use in haemodialysis (HD) patients. This study assessed the comparative safety of various antihypertensives in relation to IDH. Methods: This retrospective cohort study at a tertiary …

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Correspondence on “Severity Trend of Recurrence in Pediatric Food Protein-Induced Enterocolitis Syndrome”

Shuiying Chen, Kuan‐Hung Liu, Su‐Boon Yong, Chin‐Yuan Yii

Correspondence on “Severity Trend of Recurrence in Pediatric Food Protein-Induced Enterocolitis Syndrome”Shih-Huan Chen 1, Kuan-Hung Liu 1, Su-Boon Yong 1,2,3,4 *, Chin-Yuan Yii, MD ⁵¹School of Medicine, China Medical University Hospital, Taichung, Ta

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Longitudinal Changes in Peritoneal Transport and Their Impact on Dialysis Outcomes: A Machine Learning Approach integrating Clinical and Biomarker Data

Chia-Chun Lee, Jo-Yen Chao, Kuan‐Hung Liu, Wei-Ren Lin et autres

INTRODUCTION: Longitudinal changes in peritoneal transport patterns and the predictive role of dialysate biomarkers remain poorly understood. This study assessed the impact of peritoneal equilibration test (PET) trajectory changes on clinical outcomes, explored biomarker contributions, and developed a machine learning-based model to …

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The temporal association between percutaneous coronary intervention and intradialytic hypotension in hemodialysis patients

Tzu-Shan Huang, Jianan Wang, Wei-Ren Lin, Zheng-Zhe Wu et autres

Abstract Background Cardiovascular disease is a leading cause of mortality in end-stage kidney disease, with ischemic heart disease being prevalent. Intradialytic hypotension (IDH) is a common complication during hemodialysis (HD), with poorly understood associations with coronary artery disease and the impact of …

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CorrFill: Enhancing Faithfulness in Reference-Based Inpainting with Correspondence Guidance in Diffusion Models

Kuan‐Hung Liu, Cheng-Kun Yang, Min-Hung Chen, Yu-Lun Liu et autres

In the task of reference-based image inpainting, an additional reference image is provided to restore a damaged target image to its original state. The advancement of diffusion models, particularly Stable Diffusion, allows for simple formulations in this task. However, existing diffusion-based methods …

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Sodium–glucose cotransporter 2 (SGLT2) inhibitors and risk of chronic kidney disease–mineral and bone disorders in patients with type 2 diabetes mellitus and stage 1–3 chronic kidney disease

Daniel Hsiang‐Te Tsai, Albert Tzu-Ming Chuang, Kuan‐Hung Liu, Shih‐Chieh Shao et autres

BACKGROUND: In patients with type 2 diabetes mellitus and chronic kidney disease (CKD), sodium-glucose cotransporter 2 (SGLT2) inhibitors improve renal outcomes, but may transiently affect biochemical markers of CKD-mineral and bone disorders (CKD-MBD). We sought to evaluate the long-term risk of CKD-MBD …

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