The temporal association between percutaneous coronary intervention and intradialytic hypotension in hemodialysis patients
Rattachement africain : tw. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Background Cardiovascular disease is a leading cause of mortality in end-stage kidney disease, with ischemic heart disease being prevalent. Intradialytic hypotension (IDH) is a common complication during hemodialysis (HD), with poorly understood associations with coronary artery disease and the impact of percutaneous coronary intervention (PCI). This study examines the temporal effects of PCI on IDH in dialysis patients. Methods Patients undergoing HD at National Cheng Kung University Hospital from 1 January 2016 to 30 November 2022 were included. IDH was defined as a systolic blood pressure below 90 mmHg. HD sessions for 180 days before and after PCI were analyzed using generalized estimating equations. We calculated odds ratios (ORs) for IDH risk at various intervals relative to PCI, adjusting for demographics, comorbidities, dialysis parameters, antihypertensive medication use, and laboratory data. Results In total, 39 patients underwent 51 PCI procedures, with 6938 sessions analyzed. Within 90 days post-PCI, IDH risk decreased significantly (OR 0.667; 95% CI 0.465–0.957; P = 0.028) compared with baseline (90 days pre-PCI), but no statistically significant reduction within 91–180 days. Patients with diabetes exhibited a pronounced reduction in IDH risk within 90 days (OR 0.545; 95% CI 0.378–0.786; P = 0.001) and in 180 days (OR 0.551; 95% CI 0.379–0.799; P = 0.002). Monthly trends indicated a gradual increase in IDH risk pre-PCI, peaking 2 months prior to PCI, followed by a sustained decline during the first 3 months post-PCI. Conclusions PCI is associated with a reduction in the risk of IDH, particularly in patients with diabetes, within the first 3 months post-intervention. This study highlights the temporal benefits of PCI in managing IDH, especially in high-risk populations, such as dialysis patients with DM. Further investigation into PCI benefits is warranted.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The temporal association between percutaneous coronary intervention and intradialytic hypotension in hemodialysis patients
- Date Crossref
- 02/03/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Cheng Kung University Hospital Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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National Cheng Kung University pays non établi dans la noticeUniversité ou école supérieure
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Kuo General Hospital Division of Nephrology pays non établi dans la noticeÉtablissement de santé
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Asia University pays non établi dans la noticeUniversité ou école supérieure
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China Medical University pays non établi dans la noticeUniversité ou école supérieure
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Ministry of Health and Welfare pays non établi dans la noticeOrganisme public
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College of Medical and Health Science Department of Healthcare Administration pays non établi dans la noticeUniversité ou école supérieure
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College of Medicine Department of Public Health pays non établi dans la noticeUniversité ou école supérieure
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College of Public Health Department of Public Health pays non établi dans la noticeUniversité ou école supérieure
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School of Pharmacy pays non établi dans la noticeUniversité ou école supérieure
Department of Internal Medicine — National Cheng Kung University Hospital, National Cheng Kung University et Division of Nephrology — Kuo General Hospital, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.