L. V. Ivanova

Pharmacoeconomic study of tocilizumab dosing strategies as an intravenous solution in rheumatoid arthritis

Aleksander M. Lila, A. Vasilenko, Elena V. Gerasimova, А. И. Дубиков et autres

Tocilizumab (TCZ) is widely used in rheumatoid arthritis (RA) and may be administered using different dosing regimens, including the standard dose (SD) of 8 mg/kg and regimens involving dose reduction or escalation depending on the clinical response. Under current healthcare conditions, assessment …

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Resolution of the Expert Council “Reproductive health of patients with rheumatic diseases during targeted therapy: from preconception preparation to postpartum follow-up”

Evgeny Lvovich Nasonov, Aleksander M. Lila, Т. В. Дубинина, Pavel A. Shesternya et autres

On June 19, 2026, a meeting of the Expert Council was held to discuss reproductive health issues in patients with immune-mediated inflammatory rheumatic diseases and the safety of antirheumatic therapy. Rheumatologists, obstetrician-gynecologists, reproductive medicine specialists, and other experts participated in the discussion.

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Non-interventional multicenter study of the management of patients with non-radiographic axial spondyloarthritis in real-world clinical practice in the Russian Federation (NiSpAR): data from the prospective part

Т. В. Дубинина, Aleksander M. Lila, Ekaterina M. Agafonova, Irina A. Andrianova et autres

In the Russian Federation, there is an unmet need for research of non-radiographic (nr) axial spondyloarthritis (nr-axSpA). Therefore, the noninterventional multicenter NiSpAR study was initiated in 2022. Objective: to describe a cohort of patients with nr-axSpA and approaches to its diagnosis in …

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Steroid-sparing effect of levilimab in rheumatoid arthritis in real practice

L. V. Ivanova, E. Yu. Akulinushkina, Anastasia N. Vedekhina, N. Garaeva et autres

Aim. Evaluation in real clinical practice steroid-sparing effect of levilimab therapy in patients with highly and moderately active rheumatoid arthritis (RA). Materials and methods. Retrospective observational study (1 year) held at the Republican Clinical Diagnostic Center for the period from November 2022 …

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The Efficacy and Safety of Divozilimab in Patient with Systemic Sclerosis: 48-Week Results of the Randomized Double-Blind Placebo-Controlled Phase III Clinical Study LIBERIUS

L. P. Ananyeva, M. Starovoytova, Inna Z. Gaydukova, Galina V Lukina et autres

of the study is to evaluate the efficacy, safety, and immunogenicity of divozilimab (DIV), anti-CD20 monoclonal antibody, in patients with systemic sclerosis (SS). MATERIALS AND METHODS: Patients with SS according to ACR/EULAR (American College of Rheumatology/European Alliance of Associations for Rheumatology) 2013 …

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Use of olokizumab, a direct interleukin 6 inhibitor, in the treatment of rheumatoid arthritis: real-world evidence

Pavel A. Shesternya, Alena I. Zagrebneva, О. В. Антипова, Yu. V. Arbuzova et autres

Objective: To study the efficacy and safety of olokizumab (OKZ) in patients with rheumatoid arthritis (RA) in real-life clinical practice. Material and methods. The observational program was conducted in 73 centers across Russia from Dec 1, 2022 to Jan 31, 2025. It …

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Efficacy and safety of rapid dose escalation of methotrexate in rheumatoid arthritis. Results of the multicenter “METEOR” study

Е. Yu. Polishchuk, О. Н. Аношенкова, Irina B. Vinogradova, Elena V. Zonova et autres

The aim of the study – to analyze the effectiveness and tolerability of subcutaneous methotrexate (sc MTX) (Metorthrit; S.C. Rompharm Company S.R.L) in patients with rheumatoid arthritis (RA) with high disease activity and rapid dose escalation, to assess their quality of life …

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Efficacy of divozilimab in the treatment of systemic sclerosis: results of the randomized phase III clinical trial BCD-132-5/LIBERIUS

L. P. Ananyeva, M. Starovoytova, Inna Z. Gaydukova, Galina V Lukina et autres

The search for new therapeutic options for the treatment of systemic sclerosis (SSc) is an urgent issue in rheumatology. The article presents the results of the double-blind, randomized, placebo-controlled phase III clinical trial BCD-132-5/LIBERIUS on the efficacy and safety of divozilimab (BCD-132) …

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Results of a non-interventional multicenter observational study on the diagnosis and treatment of patients with axial psoriatic arthritis in rea-world clinical practice in the Russian Federation (NiSaXPA)

Tatiana V Korotaeva, Е. Е. Gubar, Е. Yu. Loginova, Yu. L. Kоrsakova et autres

Objective: The aim of the NiSaXPA study is to evaluate the quality of diagnosing, socio-demographic characteristics and treatment tactics of patients with axial psoriatic arthritis (axPsA) in real-world clinical practice in the Russian Federation. Material and methods. The study involved 600 patients …

ru, cz, ua, us (code pays fourni par la source)

Validation of the Russian-language version of Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire

L. D. Vorobyova, Т. В. Дубинина, Anastasiya O. Sablina, Anastasia B. Demina et autres

Objective: validation of the Russian-language version of Ankylosing Spondylitis Quality of Life (ASQoL) specific questionnaire for patients with ankylosing spondylitis (AS). Materials and methods. Тhe study included 100 patients with a definite diagnosis of AS according to the modified New York criteria …

Efficacy and safety of levilimab in the treatment of rheumatoid arthritis in real-life clinical practice: first results of the HELIOS observational study

Aleksander M. Lila, Inna Z. Gaydukova, О. Н. Аношенкова, I. G. Bannikova et autres

The efficacy and safety of levilimab (LVL) in patients with active rheumatoid arthritis (RA) has been confirmed in controlled clinical trials. This article presents the results of a preliminary analysis of a non-interventional observational study of LVL in RA patients. Objective: to …

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Results of a non-interventional multicenter study of management of patients with non-radiological axial spondyloarthritis in real-life clinical practice in the Russian Federation (NiSpAR)

Т. В. Дубинина, Aleksander M. Lila, E. V. Kvasova, Ekaterina M. Agafonova et autres

NiSpAR is a non-interventional, multicenter study whose aim was to describe a cohort of patients with non-radiological axial spondyloarthritis (nr-axSpA) and approaches to its diagnosis in the Russian Federation. Material and methods. The study involved 20 research centers in different regions of …

ru (code pays fourni par la source)