Nadeed Sadique

Interlaminar versus sublaminar lumbar decompression: a retrospective study on patient satisfaction as measured by PROMIS outcomes

Joseph P. Cavataio, Nadeed Sadique, Ali Mehaidli, Obed Barkus et autres

Background: Interlaminar and sublaminar decompressions are evolving alternatives to traditional lumbar laminectomy for managing symptomatic lumbar stenosis, but comparative patient-reported outcomes remain underexplored. This study evaluates differences in Patient-Reported Outcomes Measurement Information System (PROMIS) pain interference and physical function (PF) scores between …

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Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis

Anoop Arunagiri, Maroof Alam, Leena Haataja, Hassan Draz et autres

Primary defects in folding of mutant proinsulin can cause dominant-negative proinsulin accumulation in the endoplasmic reticulum (ER), impaired anterograde proinsulin trafficking, perturbed ER homeostasis, diminished insulin production, and β-cell dysfunction. Conversely, if primary impairment of ER-to-Golgi trafficking (which also perturbs ER homeostasis) …

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Malignant mixed mullerian tumor (mmmt) of uterus — a challenging clinico ‐ pathological problem. A case report and literature review

V. Nalini, Nadeed Sadique