A Functional FCGR2A Haplotype Associated with Rheumatoid Arthritis Determines Circulating Soluble FcγRIIa Levels and Immune Complex Signalling
Euan W. Baxter, Eleanor Foy, John Taylor, Maren Thomsen et autres
0 citationsmedRxiv
Maren Thomsen
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44Publications signalées
642Citations signalées
2Affiliations récentes
Institutions déclarées
Domaines associés
Enzyme Structure and FunctionGenetic Neurodegenerative DiseasesMonoclonal and Polyclonal Antibodies ResearchLipid Membrane Structure and BehaviorRNA Research and Splicing
Publications récentes
Cyclic Peptide Inhibitors of the MLH1-MSH3 Interaction as a Potential Therapeutic Strategy for Huntington's Disease
Tasir S. Haque, Federica Orvieto, Sara Tomaselli, Lorenzo Turcano et autres
1 citationChemRxiv
Cyclic Peptide Inhibitors of the MLH1-MSH3 Interaction as a Potential Therapeutic Strategy for Huntington's Disease
Tasir S. Haque, Federica Orvieto, Sara Tomaselli, Lorenzo Turcano et autres
0 citationsChemRxiv
Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitors
Gareth N. Brace, Karsten Tillack, Peter Johnson, Markus Ritzefeld et autres
4 citationsBioorganic & Medicinal Chemistry Letters
Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
Jung‐Hoon Lee, Maren Thomsen, Herwin Daub, Gabriel Thieulin‐Pardo et autres
4 citationsNucleic Acids Research
A FAN1 point mutation associated with accelerated Huntington’s disease progression alters its PCNA-mediated assembly on DNA
Jonas Aretz, Gayathri Jeyasankar, Anna Salerno-Kochan, Maren Thomsen et autres
5 citationsNature Communications
The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1
Joanna L. Chen, Joey L. Methot, Matthew J. Mitcheltree, Andrew J. Musacchio et autres
4 citationsACS Medicinal Chemistry Letters
Identification of orthosteric inhibitors of MutSbeta ATPase function
Gareth Brace, Karsten Tillack, Peter Johnson, Markus Ritzefeld et autres
1 citationChemRxiv
A FAN1 point mutation associated with accelerated Huntington’s disease progression alters its PCNA-mediated assembly on DNA
Jonas Aretz, Gayathri Jeyasankar, Anna Salerno-Kochan, Maren Thomsen et autres
2 citationsbioRxiv (Cold Spring Harbor Laboratory)
Cryo-EM Structures of CRAF2/14-3-32 and CRAF2/14-3-32/MEK12 Complexes
Dirk Dedden, Julius Nitsche, Elisabeth V. Schneider, Maren Thomsen et autres
12 citationsJournal of Molecular Biology
Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening
Tuomo Kalliokoski, Henna Kettunen, Esa T. T. Kumpulainen, Emilia Kettunen et autres
9 citationsBioorganic & Medicinal Chemistry Letters
POS0010 PROTEOMIC LANDSCAPE OF SYNOVIAL TISSUE IN RHEUMATOID ARTHRITIS AND DETERMINANTS OF SYNOVIAL HISTOLOGICAL PATHOTYPES
Christopher Aboo, Allan Stensballe, Christian Nielsen, Henrik Daa Schrøder et autres
2 citationsAnnals of the Rheumatic Diseases
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