Julie M. Wolf

Imaging Metabotropic Glutamate Receptor 5 and Excitatory Neural Activity in Autism

Adam J. Naples, Yanghong Yang, Paul Gravel, Takuya Toyonaga et autres

OBJECTIVE: Autism spectrum disorder is a prevalent and heterogeneous condition with features ranging from social and communication differences to sensory sensitivities. Differences in excitatory neurotransmission have been identified in autism, but the molecular underpinnings are poorly understood. To investigate the mechanism underlying …

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Brain-wide connectivity changes due to social–emotional regulation during a naturalistic fMRI task

Christopher J. Hyatt, Bruce E. Wexler, Gretchen J. Diefenbach, Gabriel S. Dichter et autres

Social-emotional (SE) regulation is necessary for successful social interactions. Such emotion regulation (ER), however, has been examined in only a few studies using naturalistic SE tasks during functional neuroimaging. We examined ER in typically developed young adults (n = 62) watching and …

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Social Anxiety Reduces Visual Attention to the Eyes of Emotional Faces in Autistic Youth

Cassandra J. Franke, Jason W. Griffin, Adam J. Naples, Julie M. Wolf et autres

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11C-UCB-J PET imaging is consistent with lower synaptic density in autistic adults

David Matuskey, Yanghong Yang, Mika Naganawa, Sheida Koohsari et autres

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Clinician–caregiver informant discrepancy is associated with sex, diagnosis age, and intervention use among autistic children

Margaret A. Azu, Gloria T. Han, Julie M. Wolf, Adam J. Naples et autres

Clinician and caregiver reports of autism features are both integral to receiving an autism diagnosis and appropriate intervention, yet informant discrepancies are present in clinical practice and may differ by demographic characteristics of the child and family. The present study examined how …

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Assessment and Treatment Planning in Autistic Adults

Cara M. Keifer, Pamela E. Ventola, Julie M. Wolf

HBV F genomes aligment

Julie M. Wolf

42.4 Excitatory/Inhibitory Neural Dynamics Associate With Sensory and Social Features Transdiagnostically

Adam J. Naples, Jennifer H. Foss‐Feig, Julie M. Wolf, Vinod H. Srihari et autres

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Development of peak alpha frequency reflects a distinct trajectory of neural maturation in autistic children

Caroline E. Finn, Gloria T. Han, Adam J. Naples, Julie M. Wolf et autres

Electroencephalographic peak alpha frequency (PAF) is a marker of neural maturation that increases with age throughout childhood. Distinct maturation of PAF is observed in children with autism spectrum disorder such that PAF does not increase with age and is instead positively associated …

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Neural correlates of eye contact and social function in autism spectrum disorder

Joy Hirsch, Xian Zhang, Jack Adam Noah, Swethasri Dravida et autres

Reluctance to make eye contact during natural interactions is a central diagnostic criterion for autism spectrum disorder (ASD). However, the underlying neural correlates for eye contacts in ASD are unknown, and diagnostic biomarkers are active areas of investigation. Here, neuroimaging, eye-tracking, and …

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Predictability modulates neural response to eye contact in ASD

Adam J. Naples, Jennifer H. Foss‐Feig, Julie M. Wolf, Vinod H. Srihari et autres

BACKGROUND: Deficits in establishing and maintaining eye-contact are early and persistent vulnerabilities of autism spectrum disorder (ASD), and the neural bases of these deficits remain elusive. A promising hypothesis is that social features of autism may reflect difficulties in making predictions about …

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Individual Symptom Severity in Adult Autism Spectrum Disorder Predicts Reduction in Right Dorsal Stream Neural Activity During Live Eye-to-Eye Contact

Joy Hirsch, Xian Zhang, Jack Adam Noah, Adam J. Naples et autres

Abstract Background Social symptomatology quantified by clinical interview (Autism Diagnostic Observation Schedule, ADOS) and self-report (Social Responsiveness Scale, SRS) indicate symptom severity in autism spectrum disorder (ASD). Reluctance to engage in interpersonal eye contact is a frequently observed behavioral hallmark, though neural …

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