Formulation Development of a COVID-19 Recombinant Spike Protein-Based Vaccine
Emily Xiao, Clémentine Mirabel, Didier Clénet, Shaolong Zhu et autres
The purpose of this study was to develop a formulation for a recombinant prefusion spike protein vaccine against SARS-CoV-2. It was found that the spike protein was susceptible to aggregation due to mechanical stress. Therefore, formulation studies were initiated focused on screening …
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