Ingrid Zahn

DMBT1 in the ocular surface system: distribution, tear levels, and implications for epithelial repair and artificial tear design

Zhaoxi Zhang, Philipp Arnold, Ingrid Zahn, Friedrich Paulsen

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A Spheroid Model of Primary Human Meibomian Gland Epithelial Cells Promotes Glandular Differentiation and Function

Gizem Çizmeci, Abdullah Ortadeveci, Julian Schwebler, Christian Lutz et autres

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A high-throughput 3D conjunctival spheroid model for standardized in vitro testing

Zhi Liang, Muhammad Aslam, Wahaj Ul Haq, Martina Wiesler et autres

New Approach Methodologies (NAMs) based on human cells are increasingly needed to improve the physiological relevance, reproducibility, and ethical acceptability of preclinical ocular surface research. We developed a reproducible and scalable three-dimensional in vitro conjunctival spheroid model using primary human conjunctival epithelial …

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Intrinsic regeneration mechanisms of murine lacrimal gland epithelial cells for therapeutic applications in aqueous-deficient dry eye disease

Ingrid Zahn, Hannah Franke, Sophie Gleixner, Nicolas Blavet et autres

PURPOSE: Aqueous-deficient dry eye disease (ADDE) results from lacrimal gland dysfunction leading to tear film instability and chronic ocular surface inflammation. Despite the gland's known regenerative potential, the intrinsic molecular mechanisms enabling epithelial recovery remain poorly understood. This study aimed to characterize …

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A systematic framework for the development and optimization of double immunofluorescence protocols across species: simultaneous visualization of blood and lymphatic vessels in human and murine tissue

Jakob Kerres, Ingrid Zahn, Jana Dietrich, Friedrich Paulsen

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The effect of excipients on the oral absorption of pimobendan in healthy dogs

Ingrid Zahn, Amanda E. Coleman, Deborah Elder, Robert D. Arnold et autres

Compounded pimobendan is prescribed without knowledge of the effect of excipients. The objective of this study was to test the effect of certain excipients on oral absorption in dogs by describing the single-dose pharmacokinetics of pimobendan and its active metabolite (o-desmethyl-pimobendan [ODMP]) …

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Corrigendum to "Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362] (Progress in Retinal and Eye Research (2025) 106, (S1350946225000357), (10.1016/j.preteyeres.2025.101362))

Michael Stopfer, Ingrid Zahn, Katharina Jüngert, Gerhard Aumüller et autres

The authors regret that. 1. There is a mistake in Fig. 2. Please change this figure with the attached figure. [Figure presented] 3. We forgot to mention under “Acknowledgments”: The present article is part of the first author's (M.S.) doctoral thesis. The …

Uptake of Micro- and Nanoplastics in Ocular Surface Cells and Impact on Cell Viability

Agatha Raffauf, Katharina Jüngert, Ingrid Zahn, Fabian Garreis et autres

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3D Cultivation of the Recently Established Human Lacrimal Gland Cell Line Serves as a Simplified Lacrimal Gland Model

Sophie Gleixner, Raphael Schwendner, Eileen Socher, Ingrid Zahn et autres

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Unraveling the Intrinsic Regeneration Mechanisms of Lacrimal Gland Acinar Epithelial Cells for Therapeutic Applications in Aqueous-Deficient Dry Eye

Ingrid Zahn, Hannah Franke, Sophie Gleixner, Jana Dietrich et autres

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Development of 3D organoids from human meibomian gland cells to investigate the effects of endocannabinoids on exocrine secretion

Gizem Çizmeci, Julian Schwebler, Christian Lutz, Friedrich Paulsen et autres

de (code pays fourni par la source)

Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]

Ingrid Zahn, Katharina Jüngert, Gerhard Aumüller, Frans L. Moll et autres

de, nl, us (code pays fourni par la source)