John McKay

Lymphoma and Lactic Acidosis

John McKay, Dominique Delbeke, Martin P. Sandler

A 39-year-old man presented with new onset of sinus congestion, shortness of breath, and diaphoresis. His laboratory tests were notable for hypercalcemia and lactic acidosis. A CT scan of the head demonstrated mild paranasal disease. CT scan of the chest, abdomen, and …

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Malignant Pheochromocytoma Metastasis to the Breast Shown on I-123 MIBG Scan

Mihir R. Patel, Peter Santos, Ian Jong, Dee Nandurkar et autres

A 36-year-old woman was referred to our department for I-123 metaiodobenzylguanidine (MIBG)-SPECT/CT scan 3 years after surgical excision of pheochromocytoma. She was referred due to recurrence of her symptoms as well as raised urinary catecholamines. Review of I-123 MIBG scan revealed multiple …

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Topical Azithromycin Therapy for Meibomian Gland Dysfunction: Clinical Response and Lipid Alterations

Gary N. Foulks, Douglas Borchman, Marta C. Yappert, Sung-Hye Kim et autres

PURPOSE: Meibomian gland dysfunction (MGD) is a common clinical problem that is often associated with evaporative dry eye disease. Alterations of the lipids of the meibomian glands have been identified in several studies of MGD. This prospective, observational, open-label clinical trial documents …

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Efficacy of milk versus water to reduce interfering infra-cardiac activity in 99mTc-sestamibi myocardial perfusion scintigraphy

Michael S. Hofman, John McKay, Dee Nandurkar

OBJECTIVE: Interference from infra-cardiac radionuclide activity prevents accurate interpretation of true myocardial perfusion. The study aim was to compare the efficacy of milk versus water in reducing infra-cardiac activity in myocardial perfusion scintigraphy. METHODS: We prospectively randomized 198 patients undergoing stress-rest (99m)Tc-sestamibi …

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Evidence of Increased Intestinal Synthesis and Extracellular Deposition of IgM in Primary Biliary Cirrhosis

Stefan Lindgren, John McKay, Ingrid Hansson, Sten Eriksson

Direct immunofluorescence showed intense extracellular granular deposition of IgM and C3 in liver and small-intestinal biopsy specimens from patients with primary biliary cirrhosis. In contrast, IgM deposits were not observed in liver tissue from patients with other liver diseases, whereas small-intestinal IgM …

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IgM Deposition in Skin Biopsies from Patients with Primary Biliary Cirrhosis

Stefan Lindgren, Sten Eriksson, Helge Löfberg, John McKay

Immunofluorescence studies on skin biopsies from 14 patients with primary biliary cirrhosis (PBC) showed granular papillary deposition of IgM in all. In addition, 6 patients had C3 deposition. Control patients with various other liver diseases, idiopathic high plasma levels of igM and …

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Evidence of increased intestinal synthesis and extracellular deposition of IgM in primary biliary cirrhosis. An immunofluorescence study of liver and small-intestinal biopsy specimens.

Stefan Lindgren, John McKay, Ingrid Hansson, Sten Eriksson

Direct immunofluorescence showed intense extracellular granular deposition of IgM and C3 in liver and small-intestinal biopsy specimens from patients with primary biliary cirrhosis. In contrast, IgM deposits were not observed in liver tissue from patients with other liver diseases, whereas small-intestinal IgM …

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Infarcts of the Pancreas

John McKay, Archie H. Bagoenstoss, Eric E. Wollaeger

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