Accès ouvert
2026
article
OpenAlex
Gilberto Vargas‐Alarcón, Oscar A Pérez-Méndez, Rosalinda Posadas‐Sánchez, Julio Cesar Domínguez-Méndez et autres
Background: Phospholipid transfer protein (PLTP) facilitates lipid transfer among plasma lipoproteins, but the contribution of this protein to coronary heart disease (CHD) remains controversial. In this context, evaluating single nucleotide polymorphisms (SNPs) in the PLTP gene, specifically rs6065904 A/G and rs378114 T/C, …
mx
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Luis E. Martínez‐Bravo, Sara G. Aguilar-Navarro, Mauricio Vazquez-Guajardo, Lidia Gutiérrez-Gutiérrez et autres
BACKGROUND: Dementia is a progressive syndrome characterized by cognitive decline. Brain atrophy has been associated with disease progression, but its predictive value in Latin American populations remains underexplored. OBJECTIVE: To assess whether brain atrophy, evaluated through visual rating scales, predicts progression from …
mx
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Teresa Juárez‐Cedillo, Nancy Martínez‐Rodríguez, Alberto Rocha‐Cruz, José Manuel Fragoso et autres
BACKGROUND: Frailty is a geriatric syndrome of multifactorial origin whose associated pathophysiological mechanisms must be studied; some inflammatory markers have recently been implicated, but the mechanisms are still not clear. In this study we have explored the relationship between cytokine polymorphisms and …
mx
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Luis E. Martínez‐Bravo, Sara G. Aguilar-Navarro, Mauricio Vazquez-Guajardo, Lidia A. Gutiérrez-Gutierrez et autres
Antecedentes: La demencia es un síndrome caracterizado por deterioro cognitivo progresivo. La atrofia cerebral se ha asociado con la progresión de la enfermedad, pero su valor predictivo en poblaciones latinoamericanas ha sido poco estudiado. Objetivo: Evaluar la relación entre la atrofia cerebral, …
mx
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Aude Nicolas, Richard Sherva, Benjamin Grenier‐Boley, Y T Kim et autres
A polygenic score (PGS) for Alzheimer’s disease (AD) was derived recently from data on genome-wide significant loci in European ancestry populations. We applied this PGS to populations in 17 European countries and observed a consistent association with the AD risk, age at …
fr, us, kr, jp, es, de, hk, cn, co, br, nl, gb, be, at, gr, ar, fi, pt, bg, cz, dk, no, se
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Gilberto Vargas‐Alarcón, Oscar A Pérez-Méndez, Rosalinda Posadas‐Sánchez, Héctor González‐Pacheco et autres
In recent years, data from genome-wide association studies (GWAS) have shown that the genes coding for transcriptional repressor GATA binding 1 (TRPS1) and tribbles pseudokinase 1 (TRIB1) play an important role in plasma lipid profiles and act as risk factors for coronary …
mx
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Antonio Valle-Medina, Claudia Camelia Calzada‐Mendoza, María Esther Ocharan-Hernández, Carlos Alberto Jiménez‐Zamarripa et autres
Alzheimer's disease (AD) is considered a global health issue with a high social burden due to the level of disability it causes in those who suffer from it. In the absence of a therapeutic alternative for this disease, we will follow one …
mx
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Teresa Juárez‐Cedillo, Nancy Martínez‐Rodríguez, Enrique Juárez‐Cedillo, Alfredo Ramı́rez et autres
Background: Dementia causes the loss of functional independence, resulting in a decrease in the quality of life of those who suffer from it. Aims: This study aimed to investigate the interactions influencing susceptibility to the development of dementia through multifactor dimensionality reduction …
mx, de
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Sara G. Aguilar-Navarro, Sara Gabriela Yeverino-Castro, Silvia Mejía-Arango, Rogelio Moctezuma et autres
To determine the burden of disease among subjects at risk of developing stroke or dementia, brain health indexes (BHI) tend to rely on anatomical features. Recent definitions emphasize the need of a broader perspective that encompasses cardiovascular risk factors (CVRFS) and lifestyle …
mx
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Jessica Sarahi Alavez-Rubio, Teresa Juárez‐Cedillo
Dementia is a syndrome in which there is deterioration in memory, behavior, and the ability to perform everyday activities. Alzheimer's disease and vascular dementia are the most common forms of dementia. There is evidence supporting the hypothesis that inflammatory and immune mechanisms …
mx
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Aude Nicolas, Richard Sherva, Benjamin Grenier‐Boley, Y. Kim et autres
A polygenic score (PGS) for Alzheimer’s disease (AD) was recently derived from data on genome-wide significant loci in European ancestry populations. We applied this PGS to populations in 17 European countries and observed a consistent association with AD risk, age at onset, …
fr, us, kr, jp, es, ar, de, hk, cn, co, br, nl, gb, be, at, gr, fi, pt, bg, cz, dk, se
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Gilberto Vargas‐Alarcón, Oscar A Pérez-Méndez, Rosalinda Posadas‐Sánchez, Héctor González‐Pacheco et autres
The role of ABO gene polymorphisms in acute coronary syndrome (ACS) and lipid metabolism is increasingly recognized. We investigated whether ABO gene polymorphisms are significantly associated with ACS and the plasma lipid profile. Six ABO gene polymorphisms (rs651007 T/C, rs579459 T/C, rs495928 …
mx
(code pays fourni par la source)