Accès ouvert
2026
article
OpenAlex
Chuanxiang Lv, Chengyu Xia, Zean Li, Tao Liu et autres
AIMS: Smoking significantly impairs cognitive function and is a major risk factor for dementia, particularly when initiated during adolescence, a critical period for brain development. The glymphatic system, which is thought to participate in metabolic waste clearance, has been implicated in maintaining …
cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Kang Zhang, Yunqian Li, Zean Li, Xinran Zhang et autres
AIMS: Spinal cord stimulation (SCS) is a promising treatment for disorders of consciousness (DoC), but early neurophysiological markers of durable recovery remain unclear. We aimed to determine whether source-space EEG network energy and communication features capture early brain-network reorganization linked to 6-month …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Liang Mi, Jiangyuan Yuan, Yuxin Jiang, Yuqian Hu et autres
The dysregulation of blood–brain barrier (BBB) activates pathological mechanisms such as neuroinflammation after traumatic brain injury (TBI), and glymphatic system dysfunction accelerates toxic waste accumulation after TBI. It is essential to find an effective way to inhibit inflammation and repair BBB and …
cn, us, au
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Chenrui Wu, Yu Shun Tian, Tao Liu, Shuo An et autres
Fluid replacement is the primary treatment for life-threatening shock but is challenging in harsh environments. This study explores low-intensity pulsed ultrasound (LIPUS) as a resuscitation strategy. Cervical LIPUS stimulation effectively elevated blood pressure in shocked rats. It also improved cerebral and multiorgan …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Zhuang Sha, Shiying Dong, Meng Nie, Tao Liu et autres
Traumatic brain injury (TBI) is a significant global health concern that often results in death or disability, and effective pharmacological treatments are lacking. G protein-coupled receptor 56 (GPR56), a potential drug target, is crucial for neuronal and glial cell function and therefore …
cn, us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Tao Liu, Yunhu Yu, Liang Mi, Zhihao Zhao et autres
Background: Traumatic brain injury (TBI) is a common neurosurgical disease in emergency rooms with poor prognosis, imposing severe burdens on patients and their families. Evidence indicates that piracetam and compound porcine cerebroside and ganglioside injection (CPCGI) can improve cognitive levels in TBI …
cn, au
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Tao Liu, Mingqi Liu, Meng Nie, Zhihao Zhao et autres
Objectives: Patients with traumatic brain injury (TBI) often suffer memory and cognitive impairments, and oxiracetam-like drugs are considered to have a positive impact on these symptoms potentially. However, the efficacy and safety of l-oxiracetam and oxiracetam in TBI patients have not been …
cn
(code pays fourni par la source)
2024
article
OpenAlex
Shiying Dong, Hongwei Zhao, Meng Nie, Zhuang Sha et autres
Traumatic brain injury (TBI) persists as a substantial clinical dilemma, largely because of the absence of effective treatments. This challenge is exacerbated by the hindered clearance of intracranial metabolic byproducts and the continual accrual of deleterious proteins. The glymphatic system (GS) and …
cn
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Zhuang Sha, Di Wu, Shiying Dong, Tao Liu et autres
This study aimed to investigate the predictive factors of therapeutic efficacy for chronic subdural hematoma (CSDH) patients receiving atorvastatin combined with dexamethasone therapy by using clinical imaging characteristics in conjunction with computed tomography (CT) texture analysis (CTTA). Clinical imaging characteristics and CT …
cn
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Tao Liu, Zhihao Zhao, Jinhao Huang, Xide Zhu et autres
BACKGROUND: Despite its prevalence, there is ongoing debate regarding the optimal management strategy for chronic subdural hematoma (CSDH), reflecting the variability in clinical presentation and treatment outcomes. This ambidirectional, nationwide, multicenter registry study aims to assess the efficacy and safety of multimodality …
cn
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Kang Zhang, Kexin Li, Chunyun Zhang, Xiaodong Li et autres
Introduction The mismatch negativity (MMN) index has been used to evaluate consciousness levels in patients with disorders of consciousness (DoC). Indeed, MMN has been validated for the diagnosis of vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS). In this study, …
cn
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Chuanxiang Lv, Shuai Han, Zhuang Sha, Mingqi Liu et autres
AIM: We aimed to assess the effects of cerebral glucagon-like peptide-1 receptor (GLP-1R) activation on the glymphatic system and whether this effect was therapeutic for traumatic brain injury (TBI). METHODS: Immunofluorescence was employed to evaluate glymphatic system function. The blood-brain barrier (BBB) …
cn
(code pays fourni par la source)