Siew Yen Chong

Neurovirulence and Immunogenicity of Attenuated Recombinant Vesicular Stomatitis Viruses in Nonhuman Primates

David K. Clarke, Farooq Nasar, Siew Yen Chong, J. Erik Johnson et autres

UNLABELLED: In previous work, a prototypic recombinant vesicular stomatitis virus Indiana serotype (rVSIV) vector expressing simian immunodeficiency virus (SIV) gag and human immunodeficiency virus type 1 (HIV-1) env antigens protected nonhuman primates (NHPs) from disease following challenge with an HIV-1/SIV recombinant (SHIV). …

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Coupling of plug flow model into Fluent simulations

Siew Yen Chong, Vishnu K. Pareek, Shaobin Wang, Moses Oludayo Tadé et autres

This paper presents a semi-empirical plug-flow reaction model for the photodegradation of formaldehyde present in indoor air in a monolith photoreactor. This semi-empirical plug-flow model was adjusted according to published experimental data to determine the average value of the illuminated surface-to-volume ratio …

CFD Simulation of a Honeycomb Monolith Photoreactor

Siew Yen Chong, Vishnu K. Pareek, Shaobin Wang, Moses Oludayo Tadé et autres

No description provided

Priming with Plasmid DNAs Expressing Interleukin-12 and Simian Immunodeficiency Virus Gag Enhances the Immunogenicity and Efficacy of an Experimental AIDS Vaccine Based on Recombinant Vesicular Stomatitis Virus

Michael A. Egan, Siew Yen Chong, Shakuntala Megati, David C. Montefiori et autres

Of the various approaches being developed as prophylactic HIV vaccines, those based on a heterologous plasmid DNA prime, live vector boost vaccination regimen appear especially promising in the nonhuman primate/simian-human immunodeficiency virus (SHIV) challenge model. In this study, we sought to determine …

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Immunogenicity of Attenuated Vesicular Stomatitis Virus Vectors Expressing HIV Type 1 Env and SIV Gag Proteins: Comparison of Intranasal and Intramuscular Vaccination Routes

Michael A. Egan, Siew Yen Chong, Nina F. Rose, Shakuntala Megathi et autres

An experimental AIDS vaccine based on attenuated, recombinant vesicular stomatitis virus (rVSV), when administered by a combination of parenteral and mucosal routes, has proven effective at preventing AIDS in a rhesus macaque model (Rose NF, et al.: Cell 2001;106:539-549). In an effort …

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In Vivo and In Vitro Analysis of IL-10 in the NZB Leukemic Model.

Brian A. McCarthy, Siew Yen Chong, George A. Parker, Monique Meramo et autres

BACKGROUND: The B-1 malignancy, CLL has been associated with a failure to undergo apoptosis and increased endogenous IL-10 production. This study was undertaken to identify IL-10 effects in the NZB murine model of CLL. MATERIALS AND METHODS: Antisense IL-10 was employed in …

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Immunogenicity of Attenuated Vesicular Stomatitis Virus Vectors Expressing HIV Type 1 Env and SIV Gag Proteins: Comparison of Intranasal and Intramuscular Vaccination Routes

Michael A. Egan, Siew Yen Chong, Nina F. Rose, Shakuntala Megati et autres

An experimental AIDS vaccine based on attenuated, recombinant vesicular stomatitis virus (rVSV), when administered by a combination of parenteral and mucosal routes, has proven effective at preventing AIDS in a rhesus macaque model (Rose NF, et al.: Cell 2001;106:539–549). In an effort …

A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques

Michael A. Egan, Siew Yen Chong, Michael Hagen, Shakuntala Megati et autres

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Studies in NZB IL-10 knockout mice of the requirement of IL-10 for progression of B-cell lymphoma

Jennifer Czarneski, Yi-Chu Lin, Siew Yen Chong, Brian A. McCarthy et autres

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Cell cycle effects of IL-10 on malignant B-1 cells

Siew Yen Chong, Y-C Lin, Jennifer Czarneski, M Zhang et autres

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The Role of B-Cell-Specific Activator Protein in the Response of Malignant B-1 Cells to LPS

Ming Zhang, Siew Yen Chong, Elizabeth S Raveche

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The growth-regulatory role of B-cell-specific activator protein in NZB malignant B-1 cells

Siew Yen Chong, Ming Zhang, Yi-Chu Lin, Frederick D. Coffman et autres

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