Accès ouvert
2026
article
OpenAlex
Hao Cheng Shen, Marie Hudson, Susanna Proudman, Jenny Walker et autres
Abstract Background Autoantibodies against NOR-90 are rare and have been associated with systemic sclerosis (SSc). This study seeks to identify the characteristics of SSc participants with anti-NOR-90 autoantibodies. Methods An international (Canada, Australia, USA, Mexico) cohort of 2143 SSc participants was included. …
ca, au, us
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Accès ouvert
2026
article
OpenAlex
Zoe Brown, Dylan Hansen, Laura Ross, Wendy Stevens et autres
Background/Objectives: Pulmonary arterial hypertension (PAH) occurs in >12% of systemic sclerosis (SSc) patients and has a high mortality. Annual screening for all SSc patients is the standard of care and can include spirometry (RFT), serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) and echocardiography …
au
(code pays fourni par la source)
Accès ouvert
2026
conference-abstract
OpenAlex
Emily Lin, Dylan Hansen, Maryam Tabesh, Laura Ross et autres
Introduction Differences between male and female patients with systemic sclerosis (SSc) have been investigated in several international cohort studies with varying foci of interest and results. However no such studies have been completed in the Australian SSc population. We sought to determine …
au
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Alannah Quinlivan, Dylan Hansen, Kathleen Morrisroe, Wendy Stevens et autres
Introduction Gastro-oesophageal reflux disease (GORD) affects up to 90% of systemic sclerosis (SSc) patients. Chronic oesophageal acid exposure can result in complications including the formation of oesophageal strictures (OS). Proton pump inhibitors (PPIs) can alter gastric acid pH and improve GORD symptoms, …
au
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Emily Lin, Dylan Hansen, Laura Ross, G. S. Ngian et autres
OBJECTIVE: The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. METHODS: This was a retrospective observational study using data from the Australian …
au
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Alannah Quinlivan, Dylan Hansen, Wendy Stevens, Nava Ferdowsi et autres
Objective Gastroesophageal reflux disease (GERD) affects up to 90% of patients with systemic sclerosis (SSc). Chronic esophageal acid exposure can result in complications including the formation of esophageal strictures (ES). Proton pump inhibitors can alter gastric acid pH and improve GORD symptoms; …
au
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Kate M. Seaton, Alannah Quinlivan, Nava Ferdowsi, Wendy Stevens et autres
INTRODUCTION: Systemic sclerosis (SSc) is a rare autoimmune disease with near-universal symptoms of gastrointestinal dysmotility. The contribution of disruption of the gut-brain axis to SSc gastrointestinal symptoms is unknown. We aimed to quantify the frequency of SSc patients meeting diagnostic criteria for …
au
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Accès ouvert
2025
article
OpenAlex
Laura Ross, Lyman Lin, Dylan Hansen, Alannah Quinlivan et autres
OBJECTIVE: Gastrointestinal involvement is almost universal in patients with systemic sclerosis (SSc). Enteric dysmotility, at its most severe, can present with pseudo-obstruction. In this study, we aimed to quantify the prevalence of SSc pseudo-obstruction and evaluate risk factors for its development. In …
au
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Kelly E. Seaton, Linda Anne Ross, Chamara Basnayake, Alannah Quinlivan et autres
Background: Systemic sclerosis (SSc) is a rare autoimmune disease that affects multiple organ systems, with up to 90% of patients reporting gastrointestinal (GI) symptoms [1]. SSc GI involvement is characterised by dysmotility, presenting with symptoms of heartburn, bloating, diarrhoea and constipation. The …
au
(code pays fourni par la source)
2024
article
OpenAlex
Lynne Taylor, Dylan Hansen, Kathleen Morrisroe, Jessica L. Fairley et autres
OBJECTIVE: The aim of this study was to determine the impact of season, temperature and humidity on the severity of Raynaud phenomenon (RP) in systemic sclerosis. METHODS: Data from the Australian Scleroderma Cohort Study were used to assess associations of patient-reported worsened …
au
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Alannah Quinlivan, Laura Ross, Nava Ferdowsi, Susanna Proudman et autres
OBJECTIVE: The gastrointestinal tract (GIT) is the most commonly affected internal organ in systemic sclerosis (SSc). We sought to determine the prevalence and impact of GIT symptoms on survival and patient-reported outcomes. METHODS: A total of 907 consecutive patients from the Australian …
au
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Alannah Quinlivan, Dennis R. Neuen, Dominique Hansen, Wendy Stevens et autres
BACKGROUND: To determine the relationship between gastroesophageal reflux disease (GORD) and its treatment and interstitial lung disease in patients with systemic sclerosis (SSc). METHODS: SSc patients from the Australian Scleroderma Cohort Study (ASCS) were included. GORD was defined as self-reported GORD symptoms, …
au
(code pays fourni par la source)