Taciana Furtado de Mendonça Belmont

Evaluation of the Association of Cytokines, Interleukin 6 Polymorphism, and Proviral Load With Myelopathy, Pain, and Functionality in HTLV1‐Infected Patients

Ana Patrícia Ferreira, Paula Machado Ribeiro Magalhães, Taciana Furtado de Mendonça Belmont, Clarice Neuenschwander Lins de Morais et autres

The factors involved in the development of functional dependence, pain and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) could be linked to inflammatory cytokines and proviral load. This study aimed to assess the association between myelopathy, pain, and functionality with proviral load in blood, …

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Association between the APOC3 (rs2854116), ESR2 (rs3020450), HFE (rs1799945), and MMP1 (rs1799750) gene polymorphisms and lipodystrophy in people living with HIV receiving antiretroviral therapy

Andreia Soares da Silva, Maria do Socorro de Mendonça Cavalcanti, Taciana Furtado de Mendonça Belmont, Ricardo Arraes de Alencar Ximenes et autres

Background The pathogenesis of lipodystrophy in people living with HIV (PLWHIV) receiving antiretrovirals appears to be multifactorial and may involve genetic factors; however, it is not yet fully understood. We verified the association between single nucleotide polymorphisms in the APOC3-rs2854116, ESR2-rs3020450, HFE-rs1799945 …

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ANÁLISE COMPARATIVA DA EXPRESSÃO DE GPX2 EM PACIENTE PORTADORES DE CARCINOMA HEPATOCELULAR E CIRROSE, COMO POTENCIAL BIOMARCADOR

João Vinícius de Oliveira Melo, Maria Eduarda Azevêdo Acioli, Ana Karla da Silva Freire, Steffany Larissa Galdino Galisa et autres

O carcinoma hepatocelular (CHC) representa o câncer hepático mais comum em todo o globo, com sobrevida estimada em até 5 anos, sendo o quarto maior responsável pelo número de óbitos ligados ao cancro anualmente.Possuindo como principal etiologia a cirrose hepática, devido ao …

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POLIMORFISMOS DO GENE HFE E SUA RELAÇÃO COM A DOENÇA HEPÁTICA GORDUROSA NÃO-ALCOÓLICA

Sérgio Ferreira, SARAH KELLYNN MEDEIROS DE SOUZA, GIOVANNA THAIS CAMPOS DE OLIVEIRA, Taciana Furtado de Mendonça Belmont

Electronic Library Online (Scielo) e Literatura Internacional em Cincias da Sade (PubMed/MEDLINE) a partir dos termos relacionados ao assunto principal e foco do estudo: "Distrbios do Metabolismo do Ferro", "Hemocromatose", "Hepatopatia Gordurosa no Alcolica", "Protena HFE" e "Sobrecarga de Ferro". Foram includos …

The role of galectin-3 in patients with permanent and paroxysmal Atrial Fibrillation and echocardiographic parameters of left atrial fibrosis

Maria Mariana Barros Melo da Silveira, João Victor Batista Cabral, Amanda Tavares Xavier, Kleyton Palmeira do Ó et autres

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The role of galectin-3 in patients with permanent and paroxysmal Atrial Fibrillation and echocardiographic parameters of left atrial fibrosis

Maria Mariana Barros Melo da Silveira, João Victor Batista Cabral, Amanda Tavares Xavier, Kleyton Palmeira do Ó et autres

Abstract Background: Atrial fibrillation (AF) is the most common type of sustained arrhythmia in clinical practice. Biochemical markers and imaging tests have been used with the aim of stratifying the risk and detecting atrial fibrosis. Speckle-tracking echocardiography (STE) is used for the …

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MicroRNA dysregulation in schistosomiasis-induced hepatic fibrosis: a systematic review

Débora Nascimento da Nóbrega, Tatiana Lins Carvalho, Kleyton Palmeira do Ó, Raul Emídio de Lima et autres

Background MicroRNAs are involved in gene regulation in several common liver diseases and may play an essential role in activating hepatic stellate cells. The role of these post-transcriptional regulators in schistosomiasis needs to be further studied in populations from endemic areas for …

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Polymorphisms and gene expression of metalloproteinases and their inhibitors associated with cerebral ischemic stroke in young patients with sickle cell anemia

Kleyton Palmeira do Ó, Ana Karla da Silva Freire, Débora Nascimento da Nóbrega, Roberta dos Santos Souza et autres

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Polymorphisms and expression of MMPs-TIMPs genes associated with cerebral ischemic stroke in young patients with sickle cell anemia

Kleyton Palmeira do Ó, Ana Karla da Silva Freire, Débora Nascimento da Nóbrega, Roberta dos Santos Souza et autres

Abstract Background Sickle cell anemia (SCA) is a genetic disease with great clinical heterogeneity and few viable strategies for treatment; hydroxyurea (HU) is the only widely used drug. Thus, the study of single nucleotide polymorphisms (SNPs) and the gene expression of MMPs …

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Potential role of circulating miR-21 in the diagnosis of hepatocellular carcinoma: a systematic review and meta-analysis

Ana Karla da Silva Freire, Taciana Furtado de Mendonça Belmont, Edgo Jackson Pinto Santiago, Isabela Cristina Cordeiro Farias et autres

OBJECTIVE: Identify original articles that analyzed the diagnostic value of miR-21 in hepatocellular carcinoma without language restriction or publication date. METHODOLOGY: We performed structured searches on PubMed, Web of Science, VHL, and EMBASE. The Standard Quality Assessment Criteria for Evaluating Primary Research …

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TRATAMENTO DE SÍNDROME MIELODISPLÁSICA DE ALTO RISCO COM AZACITIDINA E TRANSPLANTE DE MEDULA ÓSSEA HAPLOIDÊNTICO: RELATO DE UM CASO

JP Sielfeld, Taciana Furtado de Mendonça Belmont, HB Niero, LH Tagnin et autres

As síndromes mielodisplásicas agrupam doenças hematológicas que são caracterizadas por defeitos clonais nas células progenitoras, apresentando quadros variáveis de insuficiência medular, principalmente pancitopenias. Possui um risco elevado de evoluir para leucemia mieloide aguda. O risco de transformação é avaliado com base no …

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The 1G/1G+1G/2G Genotypes of MMP1 rs1799750 Are Associated with Higher Levels of MMP-1 and Are Both Associated with Lipodystrophy in People Living with HIV on Antiretroviral Therapy

Andreia Soares da Silva, Maria do Socorro de Mendonça Cavalcanti, Taciana Furtado de Mendonça Belmont, Ricardo Arraes de Alencar Ximenes et autres

In HIV-infected patients, antiretroviral therapy (ART) is associated to adipose tissue redistribution known as lipodystrophy (LD). This study aimed at verifying the association between the polymorphism of the MMP1 gene (rs1799750) (1G/2G) and the serum levels of matrix metalloproteinase 1 (MMP-1) with …

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