2025
article
OpenAlex
D Di Vece, V Schweiger, O Ohlendorf, S Roell et autres
Abstract Background Psychiatric disorders have been reported with a high prevalence in patients with Takotsubo syndrome (TTS). However, the clinical characteristics and outcomes of this specific patient subgroup remain underexplored. Purpose This study aimed to provide a detailed assessment of the clinical …
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Accès ouvert
2025
article
OpenAlex
Florian Siegerist, Eleonora Hay, Elke Hammer, Anna Iervolino et autres
BACKGROUND: Podocyte dysfunction is central to various glomerular diseases, necessitating reliable biomarkers for early detection and diagnosis. This study investigates the regulatory mechanisms of membrane-associated guanylate kinase inverted 2 (MAGI2) and its potential as a biomarker for podocytopathies. METHODS: Using fluorescence confocal …
de, it, gr, fr
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Florian Siegerist, Eleonora Hay, Elke Hammer, Anna Iervolino et autres
Abstract Podocyte dysfunction is central to various glomerular diseases, necessitating reliable biomarkers for early detection and diagnosis. This study investigates the regulatory mechanisms of membrane-associated guanylate kinase inverted 2 (MAGI2) and its potential as a biomarker for podocytopathies. The expression of the …
de, it, gr, fr
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Florian Siegerist, Svenja Kitzel, Nihal Telli, Juan Saydou Dikou et autres
Deep insights into the complex cellular and molecular changes occurring during (patho-)physiological conditions are essential for understanding the interactions and regulation of proteins. This understanding is crucial for research and diagnostics. However, the effectiveness of conventional immunofluorescence and light microscope, tools for …
de, fr
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Florian Siegerist, Svenja Kitzel, Nihal Telli, Juan Saydou Dikou et autres
Abstract Deep insights into the complex cellular and molecular changes occurring during different (patho-)physiological conditions are essential for understanding the interactions and regulation of different proteins. This understanding is crucial for both research and diagnostics. However, the effectiveness of conventional immunofluorescence, an …
de, fr
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Florian Siegerist, Eleonora Hay, Juan Saydou Dikou, Marion J. Pollheimer et autres
Increasing the information depth of single kidney biopsies can improve diagnostic precision, personalized medicine and accelerate basic kidney research. Until now, information on mRNA abundance and morphologic analysis has been obtained from different samples, missing out on the spatial context and single-cell …
de, it, at, fr
(code pays fourni par la source)
Accès ouvert
2021
preprint
OpenAlex
Florian Siegerist, Eleonora Hay, Juan Saydou Dikou, Anja Büscher et autres
Abstract Increasing the information depth of single kidney biopsies can improve diagnostic precision, personalized medicine and accelerate basic kidney research. Until now, information on mRNA abundance and morphologic analysis has been obtained from different samples, missing out on the spatial context and …
de, it, fr
(code pays fourni par la source)