Hyangkyu Lee

New-onset diabetes mellitus after pancreatectomy: A scoping review

Jeongwon Huh, Jeongeun Choi, Hyangkyu Lee

kr (code pays fourni par la source)

Digital Self-Efficacy, Satisfaction With the Daily Life Changes Stemming From Digital Transformation, and the Moderating Effect of Social Capital in Middle-Aged and Older Adults: Cross-Sectional Survey Study

Jeongeun Choi, Hyeonmi Cho, Hyangkyu Lee

Background: The swift pace of digital transformation has heightened individuals' dependence on digital technologies. This makes it imperative to explore how individual factors such as digital self-efficacy and social capital affect satisfaction with the daily life changes stemming from digital transformation. This …

kr (code pays fourni par la source)

Development of a machine learning–based sepsis prediction model for real-world clinical settings in South Korea: a single-center retrospective study

Hye Eun Hwang, Jungmin You, Min Su Kim, Da young Kim et autres

Purpose: This study aimed to develop a predictive model for the early identification of patients at risk of sepsis, using routinely available clinical information and laboratory test results collected during the initial phase of patient care. Methods: This retrospective analysis included electronic …

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Analysis of Factors Related to Delirium in Hospitalized Cancer Patients in General Wards

Sojeong Park, Hyangkyu Lee, Mona Choi, Hyejin Kim

Purpose: This study aimed to identify the incidence and related factors of delirium among cancer patients admitted to the general wards of a tertiary hospital.Methods: A retrospective analysis was performed on 9,749 adult cancer patients.Patients who screened positive for delirium were assessed …

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Postoperative Inflammatory Markers in Older Adults: A Longitudinal Study of Delirium After Spine Surgery

Jeongeun Choi, Hyangkyu Lee

Abstract Systemic inflammation is linked to postoperative delirium (POD) and adverse postoperative outcomes in older adults undergoing spine surgery. Previous studies have primarily focused on cytokine changes, limiting clinical applicability. This study aimed to examine changes in blood-based clinical inflammatory biomarker levels …

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Bacterial extracellular vesicle as a predictive biomarker for postoperative delirium status after spinal surgery: a prospective cohort study

Jai J. Jee, Sujung Park, Jeong‐Min Kim, Hyangkyu Lee et autres

BACKGROUND: Prognostic factors significantly associated with postoperative delirium (POD) have been reported discordantly, possibly due to heterogeneous cohorts. Here, bacteria extracellular vesicles (BEVs) were introduced to predict the POD status of a unique patient cohort. METHODS: One hundred twenty-eight patients who underwent …

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The Process of Cancer Prevention Behaviors in Individuals at High Risk of Hereditary Cancer: A Grounded Theory Study

Kyunghwa Lee, Sue Kim, Hyangkyu Lee, Sanghee Kim et autres

OBJECTIVE: This study aimed to explore the process of cancer prevention behaviors in individuals at high risk of hereditary cancer in Korea. METHODS: We included 10 adults with pathogenic variants in genes related to hereditary breast and ovarian cancer syndrome, hereditary non-polyposis …

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Cognitive Function, Physical Activity, and Sweat Cytokines in Older Adults With Dementia

Jo Woon Seok, Ae Young Cho, Ji Yeon Lee, Hyangkyu Lee et autres

BACKGROUND: Inflammatory cytokines are linked to cognitive function in older adults with dementia; however, their associations with physical activity (PA) and noninvasive biomarkers, such as sweat, remain unclear. OBJECTIVES: This study aimed to examine the relationships among cognitive function, PA, and sweat …

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Sodium-Glucose Cotransporter-2 Inhibitor Enhances Hepatic Gluconeogenesis and Reduces Lipid Accumulation via AMPK-SIRT1 Activation and Autophagy Induction

Hyunki Park, Min Young Lee, Hyangkyu Lee

BACKGRUOUND: Sodium-glucose cotransporter type 2 (SGLT2) inhibitors, such as dapagliflozin, are primarily used to lower glucose in type 2 diabetes. Recent studies suggest broader metabolic effects, particularly in the liver. This study explores the molecular mechanisms by which dapagliflozin influences hepatic glucose …

kr (code pays fourni par la source)

Heterogeneous Circadian Rhythms, Sleep Patterns, and Hormone Levels in Older Adults Living With Dementia

Eunhee Cho, Hyangkyu Lee, Jo Woon Seok

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The effect of an internet of things-based mobile health management application for older adults depending on user engagement in South Korea: a secondary analysis of a quasi-experimental study

Jeongeun Choi, Hyeonmi Cho, Jo Woon Seok, Hyangkyu Lee

Purpose: This study aimed to evaluate the effect of the TouchCare system, a digital health management system utilizing the internet of things (IoT), based on the usage levels of older adults. Methods: This is a secondary analysis of data from a quasi-experimental …

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BLOOD BIOMARKERS ASSOCIATED WITH POSTOPERATIVE DELIRIUM INCIDENCE, SEVERITY, DURATION AND SUBTYPE

Hyangkyu Lee, Hyeonmi Cho, Jeongeun Choi, Hyunki Park

Abstract To evaluate the associations of neurological biomarkers —specifically tau, phosphorylated tau, amyloid β40, amyloid β42, amyloid β42/40 ratio, glial fibrillary acid protein (GFAP), neurofilament light (NfL), and brain-derived neurotrophic factor (BDNF) —with the incidence, severity, duration, and subtype of postoperative delirium. …

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