Karola Trescher

Transcatheter vs. surgical aortic valve replacement in women: the RHEIA trial

Didier Tchétché, Philippe Pîbarot, Jeroen J. Bax, Nikolaos Bonaros et autres

BACKGROUND AND AIMS: Although women with severe symptomatic aortic stenosis have more complications than men when undergoing surgical valve replacement, they are under-represented in clinical trials. The Randomized researcH in womEn all comers wIth Aortic stenosis (RHEIA) trial investigates the balance of …

fr, us, ca, nl, at, ch, gb, de, it, cz (code pays fourni par la source)

The expression and role of tenascin C in abdominal aortic aneurysm formation and progression

Felix Nagel, Anne‐Kristin Schaefer, Inês Gonçalves, Eylem Acar et autres

OBJECTIVES: Up-regulation of tenascin C (TNC), a matricellular protein, produced mainly by vascular smooth muscle cells (VSMC), is associated with the progression and dilation of abdominal aortic aneurysms (AAA). The aims of this study were (i) to evaluate whether serum levels of …

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Association between sternal wound complications and 10-year mortality following coronary artery bypass grafting

Mario Gaudino, Katia Audisio, Mohamed Rahouma, N. Bryce Robinson et autres

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Postoperative Atrial Fibrillation and Long-Term Risk of Stroke After Isolated Coronary Artery Bypass Graft Surgery

Umberto Benedetto, Mario Gaudino, Arnaldo Dimagli, Stephen Gerry et autres

Background: Postoperative atrial fibrillation (pAF) after coronary artery bypass grafting is a common complication. Whether pAF is associated with an increased risk of cerebrovascular accident (CVA) remains uncertain. We investigated the association between pAF and long-term risk of CVA by performing a …

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Tenascin-C Aggravates Ventricular Dilatation and Angiotensin-Converting Enzyme Activity After Myocardial Infarction in Mice

David Santer, Felix Nagel, Inês Gonçalves, Christoph Kaun et autres

AIMS: Tenascin-C (TN-C) is suggested to be detrimental in cardiac remodelling after myocardial infarction (MI). The aim of this study is to reveal the effects of TN-C on extracellular matrix organization and its haemodynamic influence in an experimental mouse model of MI …

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The impact of age on cardiac function and extracellular matrix component expression in adverse post-infarction remodeling in mice

Felix Nagel, David Santer, Stefan Stojković, Christoph Kaun et autres

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P4549Tenascin-C deficiency attenuates abdominal aortic aneurysm progression in mice

Felix Nagel, Anne‐Kristin Schaefer, Inês Gonçalves, Philipp Kaiser et autres

Background: Tenascin-C (TNC) is a matricellular protein produced mainly by vascular smooth muscle cells (VSMC) as well as fibroblasts and plays a role in various pathological remodeling processes, including abdominal aortic aneurysms (AAA). Purpose: The aims of this study are to evaluate …

at (code pays fourni par la source)

P100Tenascin-C is induced by chronic hypoxia in cardiomyoblasts and exacerbates post myocardial infarction remodeling

David Santer, Inês Gonçalves, Felix Nagel, Attila Kiss et autres

Funding Acknowledgements: Ludwig Boltzmann Cluster for Cardiovascular Research (REM project) On behalf of: Vienna Working Heart Research Group Aims The overexpression of Tenascin-C (TNC) following myocardial infarction (MI) is associated with adverse left ventricular (LV) remodeling and poor cardiac function. The aim …

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Incidence and clinical implications of intraoperative bilateral internal thoracic artery graft conversion: Insights from the Arterial Revascularization Trial

Umberto Benedetto, Douglas G. Altman, Marcus Flather, Stephen Gerry et autres

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Tenascin-C promotes chronic pressure overload-induced cardiac dysfunction, hypertrophy and myocardial fibrosis

Bruno K. Podesser, Maximilian Kreibich, Elda Dzilic, David Santer et autres

AIMS: Left ventricular (LV) hypertrophy is characterized by cardiomyocyte hypertrophy and interstitial fibrosis ultimately leading to increased myocardial stiffness and reduced contractility. There is substantial evidence that the altered expression of matrix metalloproteinases (MMP) and Tenascin-C (TN-C) are associated with the progression …

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Short-term clinical outcomes for intermittent cold versus intermittent warm blood cardioplegia in 2200 adult cardiac surgery patients

Karola Trescher, Andreas Gleiß, Michaela Boxleitner, Wolfgang Dietl et autres

BACKGROUND: Aim of the present study was to compare clinical outcome of intermittent cold (ICC) versus intermittent warm (IWC) blood cardioplegia in different cardiosurgical procedures. METHODS: Two thousand one hundred and eighty-eight patients were retrospectively divided into 5 groups: isolated coronary artery …

at (code pays fourni par la source)

Tenascin-C deficiency attenuates abdominal aortic aneurysm formation

Anne‐Kristin Schaefer, Felix Nagel, Philipp Kaiser, David Santer et autres

at (code pays fourni par la source)