Kenneth Chan

Assessing accuracy, readability & reliability of AI-generated patient leaflets on Descemet membrane endothelial keratoplasty

Bnar Massraf, Kenneth Chan, Nikhil Jain, Jesse Panthagani

PurposeThis study assessed the readability, reliability and accuracy of patient information leaflets on Descemet Membrane Endothelial Keratoplasty (DMEK), generated by seven large language models (LLMs). The aim was to determine which LLM produced the most patient-friendly, comprehensible and evidence-based leaflet, measured against …

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Sarcoidosis presenting as a suspected metastasis around the optic disc

James Corbett, Kenneth Chan, Jesse Gale

We present a case of systemic sarcoidosis presenting with mild blurred vision, limitation of left eye movements and choroidal infiltration around the left optic disc. Symptoms and signs of inflammation were absent, and secondary malignancy was suspected. After a prolonged series of …

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Prospective study of surgical outcomes and bleb morphology using indocyanine green as a surgical dye in trabeculectomy with mitomycin C

Kenneth Chan, Ghee Soon Ang, Wayne Birchall, Tracey Wong et autres

BACKGROUND: To investigate the effect of adding indocyanine green to mitomycin C in augmented trabeculectomy. DESIGN: A prospective, non-comparative interventional case series. PARTICIPANTS: A total of 37 eyes of 37 patients followed up for 1 year. METHODS: A solution containing 12.5 mg/mL …

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Comparison of standard trabeculectomy versus microtrabeculectomy as a surgical treatment for glaucoma: a randomized clinical trial

Ghee Soon Ang, Kenneth Chan, Ali Poostchi, Simon Nicholas et autres

BACKGROUND: To determine the effect of scleral flap size on the medium-term intraocular pressure control and complication rates after augmented trabeculectomy. DESIGN: Prospective randomized clinical trial. PARTICIPANTS: Glaucoma patients undergoing primary trabeculectomy. Exclusion criteria included previous ocular surgery apart from cataract surgery, …

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Optic disc area and correlation with central corneal thickness, corneal hysteresis and ocular pulse amplitude in glaucoma patients and controls

Elizabeth A. Insull, Simon Nicholas, Ghee Soon Ang, Ali Poostchi et autres

BACKGROUND: To examine the relationships between optic disc area and parameters measured at the cornea; central corneal thickness (CCT), corneal hysteresis (CH) and ocular pulse amplitude (OPA) in glaucoma subjects and controls. METHODS: In this prospective experimental study, patients underwent measurement of …

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Optic Disc Diameter Increases during Acute Elevations of Intraocular Pressure

Ali Poostchi, Tracey Wong, Kenneth Chan, Lance Kedzlie et autres

PURPOSE: To evaluate optic nerve diameter changes in glaucomatous and nonglaucomatous eyes during transient elevation of intraocular pressure (IOP). METHODS: This prospective experimental study included 100 subjects: 38 with glaucoma and 62 without glaucoma. Elevation of IOP to an average of 64 …

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Corneal Hysteresis but Not Corneal Thickness Correlates with Optic Nerve Surface Compliance in Glaucoma Patients

Anthony P. Wells, David F. Garway‐Heath, Ali Poostchi, Tracey Wong et autres

PURPOSE: To investigate relationships between acute intraocular pressure (IOP)-induced optic nerve head surface deformation and corneal hysteresis and thickness in glaucomatous and nonglaucomatous human eyes. METHODS: This was a prospective experimental study of 100 subjects (38 with glaucoma, 62 without glaucoma). Data …

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Acute angle closure after implantable contact lens insertion unresponsive to surgical peripheral iridectomy

Kenneth Chan, Wayne Birchall, Trevor Gray, Anthony P. Wells

We present a case of acute angle closure that occurred after insertion of an implantable contact lens (ICL). The apparent papillary-block angle closure did not resolve after 2 patent iridotomies and a surgical iridectomy, but did respond to pupil dilation (not constriction). …

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Visual Field Changes after Transient Elevation of Intraocular Pressure in Eyes with and without Glaucoma

Kenneth Chan, Ali Poostchi, Tracey Wong, Elizabeth A. Insull et autres

Pilot study of the short-term physico-chemical stability of atenolol tablets stored in a multi-compartment compliance aid

Kenneth Chan, Julian Swinden, Parastou Donyai

Study objectives: There is a possibility that lower air, moisture and light protection could impact on physico-chemical stability of medicines inside multi-compartment compliance aids (MCCAs), although this has not yet been proved. The objectives of the study were to examine the physico-chemical …