Qi Xiong

Prevention of recurrence of intrauterine adhesions after hysteroscopic adhesiolysis: a systematic review and network meta-analysis of randomized controlled trials

Weiru Song, Yinghao Ma, Qi Xiong, Qingxiang Hou et autres

The aim of this network meta-analysis (NMA) is to comprehensively analyze the effectiveness of different postoperative interventions for Intrauterine adhesion (IUA) recurrence prevention. Literature searching was performed to select eligible studies published prior to March 11, 2026 in PubMed, Cochrane and Embase. …

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MUSASHI1 promotes tau phosphorylation by activating the p38 MAPK pathway

Wenshuang Li, Baomiao Ma, Xiang Tian, Qi Xiong et autres

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Low-dose chemotherapy combined with delayed immunotherapy in the neoadjuvant treatment of non-small cell lung cancer and dynamic monitoring of the drug response in peripheral blood

Chaoyang Liang, Qi Song, Wenhao Zhou, Na Li et autres

Abstract Background Despite chemo-immunotherapy has been applied to the neoadjuvant treatment of non-small cell lung cancer (NSCLC), the impacts of dosage and the order of medication on treatment efficacy and safety remain largely unexplored. We originally designed an exploratory study to investigate …

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Author response: Low-dose chemotherapy combined with delayed immunotherapy in the neoadjuvant treatment of non-small cell lung cancer and dynamic monitoring of the drug response in peripheral blood

Chaoyang Liang, Qi Song, Wenhao Zhou, Na Li et autres

Despite chemo-immunotherapy has been applied to the neoadjuvant treatment of non-small cell lung cancer (NSCLC), the impacts of dosage and the order of medication on treatment efficacy and safety remain largely unexplored. We originally designed an exploratory study to investigate the efficacy …

Efficacy and safety of first-line chemoimmunotherapy in young patients with extensive-stage small cell lung cancer: a multicenter retrospective study

Lijuan Zhao, Qi Xiong, Yaping Long, Haiming Hu et autres

OBJECTIVES: Chemoimmunotherapy is the first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). This study aims to evaluate the survival outcomes and safety of chemoimmunotherapy in young patients with ES-SCLC. PATIENTS AND METHODS: Patients with pathologically or cytologically confirmed ES-SCLC from three …

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Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance

Qingqing Xu, Xin Liu, Yibo Zhang, Shiyu Yuan et autres

Background Clusterin (CLU) is a multifunctional protein involved in various pathophysiological processes and diseases. Glioma, the most common aggressive primary brain tumor, is characterized by high morbidity, mortality, and extremely poor prognosis. Our research has found that CLU is upregulated in glioma …

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RETRACTED: Meta-analysis of the synergistic effect of traditional Chinese medicine compounds combined with conventional Western medicine in the treatment of osteoporosis

Huan Jin, Cai Huang, Yan Zhang, Ying Dong et autres

Background: As a global public health problem, osteoporosis (OP) urgently requires better treatment strategies. This study systematically evaluated the synergistic effect of traditional Chinese medicine (TCM) compounds combined with conventional Western medicine (such as bisphosphonates and calcium) compared to Western medicine alone …

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Comparative efficacy of teriparatide and bisphosphonates or denosumab vs. teriparatide monotherapy in osteoporosis: a meta-analysis

Cai Huang, Yan Zhang, Ying Dong, Qi Xiong et autres

Introduction: Teriparatide (TPTD), a widely used bone-promoting drug in osteoporosis (OP) treatment, may cause compensatory bone resorption with long-term monotherapy (>6 months). Combining TPTD with anti-bone resorption drugs (e.g., bisphosphonates and denosumab) could reduce bone loss, yet existing randomised controlled trials (RCTs) …

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Development of a Three-dimensional Gel Culture Model of Caenorhabditis elegans Muscular Atrophy Induced by Acoustic Levitation Simulating Microgravity

Shuning Hu, Zhou Yu, Qi Xiong, Ke Zhang et autres

Aims: This study aimed to establish an acoustic levitation-based microgravity simulation model and investigate its effects on the locomotor function and muscle protein expression of Caenorhabditis elegans. Methodology: L4-stage N2 nematodes were assessed on gel ball and on culture plate after 3-, …

Clec7a Signaling in Microglia Promotes Synapse Loss Associated with Tauopathy

Ji Wang, Yongkang Cao, Yibo Zhang, Zhuoran Sun et autres

Alzheimer's disease (AD) pathogenesis involves progressive synaptic degeneration, a process potentially driven by maladaptive microglial pruning activity. While synaptic loss is a hallmark of AD, the molecular signals triggering pathological microglia-mediated synaptic engulfment remain elusive. Clec7a-a key marker of disease-associated microglia (DAM)-is …

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Vimentin Fragmentation and Its Role in Amyloid-Beta Plaque Deposition in Alzheimer’s Disease

Lan Zhang, Ji Wang, Yalong Yan, Xinyue Zhai et autres

Intermediate filament protein vimentin (Vim) is a well-established marker for reactive astrocytes and has been closely associated with Alzheimer's disease (AD). RNA sequencing data reveal elevated expression of Vim in AD brains, with its aggregation frequently observed around amyloid-β (Aβ) plaques. However, …

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Low-dose chemotherapy combined with delayed immunotherapy in the neoadjuvant treatment of non-small cell lung cancer and dynamic monitoring of the drug response in peripheral blood

Chaoyang Liang, Qi Song, Wenhao Zhou, Na Li et autres

Abstract Background Despite chemo-immunotherapy has been applied to the neoadjuvant treatment of non-small cell lung cancer (NSCLC), the impacts of dosage and the order of medication on treatment efficacy and safety remain largely unexplored. We originally designed an exploratory study to investigate …

cn (code pays fourni par la source)