Stéphane Bounan

Safety of prostaglandins in the peripartum period in case of sickle‐cell disease: A multicenter cohort study

Mayi Gnofam, Jeanne Sibiude, Louis Affo, Frederic Galactéros et autres

Abstract Introduction Pregnancies with sickle‐cell disease are at high risk of maternal, obstetrical, and fetal complications, for which prostaglandins are often indicated to induce labor or to treat postpartum hemorrhage. There is concern that prostaglandin use may increase the risk of vaso‐occlusion, …

fr, mq, in (code pays fourni par la source)

Immunologic aspects of preeclampsia

Henri Boulanger, Stéphane Bounan, Amel Mahdhi, Dominique Drouin et autres

Preeclampsia is a syndrome with multiple etiologies. The diagnosis can be made without proteinuria in the presence of dysfunction of at least 1 organ associated with hypertension. The common pathophysiological pathway includes endothelial cell activation, intravascular inflammation, and syncytiotrophoblast stress. There is …

fr, us (code pays fourni par la source)

Devenir obstétrical des vomissements maternels du premier trimestre en relation avec la fonction thyroïdienne

F. Chiche, M. Fysekidis, F. Ferhat, Stéphane Bounan et autres

fr (code pays fourni par la source)

Neonatal Outcomes for Women at Risk of Preterm Delivery Given Half Dose Versus Full Dose of Antenatal Betamethasone: A Randomized, Multicenter, Double-blind, Placebo-controlled, Noninferiority Trial

Thomas Schmitz, Muriel Doret-Dion, Loı̈c Sentilhes, Olivier Parant et autres

(Lancet. 2022;400:592–604) Antenatal corticosteroids are recommended worldwide to help premature fetus lung maturity. However, the current recommended dose may be too high, based on some neurological, mental, and behavioral side effects. This study compared a half-dose (12 mg) of antenatal betamethasone to …

fr (code pays fourni par la source)

Impact of prenatal corticosteroid therapy on sickle cell disease in pregnant women

Florence Wang, Laurent Mandelbrot, Louis Affo, Frederic Galactéros et autres

OBJECTIVE: To evaluate safety of prenatal corticosteroids in pregnancies of women with sickle cell disease. METHODS: A multicenter observational study of patients with sickle cell disease, comparing vaso-occlusive crises (VOC) requiring hospital care between pregnancies with versus without prenatal corticosteroids. RESULTS: In …

fr, mq (code pays fourni par la source)

Neonatal Outcomes for Women at Risk of Preterm Delivery Given Half Dose Versus Full Dose of Antenatal Betamethasone: A Randomized, Multicentre, Double-blind, Placebo-Controlled, Non-inferiority Trial

Thomas Schmitz, Muriel Doret-Dion, Loı̈c Sentilhes, Olivier Parant et autres

ABSTRACT Antenatal corticosteroid administration to women at risk of preterm delivery is recommended worldwide because of their effectiveness in preventing respiratory distress syndrome, as well as in reducing the rate of necrotizing enterocolitis, intraventricular hemorrhage, and neonatal death in preterm infants. However, …

Impact of antenatal corticosteroid therapy on sickle cell disease in pregnant women

Florence Wang, Laurent Mandelbrot, Louis Affo, F. Galactéros et autres

fr, in (code pays fourni par la source)

Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial

Thomas Schmitz, Muriel Doret-Dion, Loı̈c Sentilhes, Olivier Parant et autres

fr, ch (code pays fourni par la source)

Mid-trimester miscarriage and subsequent pregnancy outcomes: the role of cervical insufficiency in a cohort of 175 cases

M. Joubert, Jeanne Sibiude, Stéphane Bounan, Laurent Mandelbrot

OBJECTIVE: To evaluate the causes of MTM and their impact on subsequent pregnancies. MATERIAL AND METHODS: A retrospective single-center cohort study of all pregnancies with a second-trimester pregnancy loss between 14 weeks and 21 weeks + 6 days gestation, excluding terminations of …

fr (code pays fourni par la source)

Rilpivirine in HIV-1-positive women initiating pregnancy: to switch or not to switch?

Pierre Frange, Roland Tubiana, Jeanne Sibiude, Ana Canestri et autres

BACKGROUND: Safety data about rilpivirine use during pregnancy remain scarce, and rilpivirine plasma concentrations are reduced during second/third trimesters, with a potential risk of viral breakthroughs. Thus, French guidelines recommend switching to rilpivirine-free combinations (RFCs) during pregnancy. OBJECTIVES: To describe the characteristics …

fr, gb (code pays fourni par la source)

Delayed-interval delivery of twins in 13 pregnancies

Margaux Louchet, Chloé Dussaux, Dominique Luton, François Goffinet et autres

fr (code pays fourni par la source)

Staffing needs for unscheduled activity in obstetrics and gynecology

Loı̈c Sentilhes, Fabienne Galley-Raulin, C. Boithias, Michel Sfez et autres

fr, us (code pays fourni par la source)