Apoorva Ayachit

Neovascular age-related macular degeneration management – Beyond anti-VEGF

Apoorva Ayachit, Shailesh Rao, Shadma Eqbal, Giriraj Vibhute et autres

Intravitreal anti-vascular endothelial growth factor (VEGF) therapy has transformed neovascular age-related macular degeneration (nAMD) into a chronic, treatable condition. However, real-world outcomes remain limited by treatment burden, limited durability, variable response, and progression of atrophy or fibrosis, highlighting the need for strategies …

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Non-intravitreal anti-vascular endothelial growth factor delivery for ocular neovascular diseases: Current status and future directions

Shrinivas M Joshi, Giriraj Vibhute, Shailesh M. Rao, Apoorva Ayachit et autres

Intravitreal anti-vascular endothelial growth factor (VEGF) therapy has fundamentally transformed the management of retinal and choroidal neovascular diseases. Despite its proven efficacy, long-term reliance on repeated intravitreal injections imposes a substantial burden on patients and healthcare systems. Real-world studies consistently demonstrate reduced …

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Comparison of Intraoperative Fluorescein Angiography–Guided Lavage Versus Conventional Lavage in Delayed Postoperative Vitreous Cavity Hemorrhage

Hrishikesh Naik, Shrinivas Joshi, Guruprasad S. Ayachit, Siddharth Singh Maanju et autres

Purpose: To compare outcomes of vitreous lavage with and without intraoperative fluorescein angiography (FA) in eyes with delayed postoperative vitreous cavity hemorrhage. Methods: This prospective case-control study included patients with postoperative vitreous cavity hemorrhage who were randomized into 2 groups (intraoperative FA …

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Are the SUN Criteria Sufficient for Tubercular Uveitis? Findings From a Multinational Registry Study

A. U‐L. See, William Andrés Rojas-Carabali, Carlos Cifuentes-González, Atul Arora et autres

Purpose: The Standardization of Uveitis Nomenclature (SUN) criteria were introduced in 2021 to standardize the classification of uveitis subtypes. We evaluated the real-world applicability of these criteria for tubercular uveitis (TBU) using a computational definition mapped to the Ocular Autoimmune Systemic Inflammatory …

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Acute Aggressive Posterior Progressive Necrotising Retinitis: Re-Evaluating Progressive Outer Retinal Necrosis

Akshita Aggarwal, Spoorti Krishna Reddy Mandadi, Avinash Pathengay, Rajeev Reddy Pappuru et autres

PURPOSE: The aim of this paper is to describe and analyse the retinal involvement and Optical Coherence Tomography (OCT) findings in Progressive Outer Retinal Necrosis (PORN) and revisiting its terminology. METHODS: Retrospective review of 26 eyes of 15 HIV-positive patients diagnosed with …

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Clinical and Imaging Spectrum of Laser-Induced Maculopathy Caused by Laser Projection Devices

Siddharth Maanju, Giriraj Vibhute, Guruprasad S. Ayachit, Apoorva Ayachit

PURPOSE: This study highlights the spectrum of fundus and optical coherence tomography (OCT) findings in a cluster of cases of laser-induced maculopathy and their management. METHODS: This single-centre prospective study enrolled 17 eyes from 17 patients diagnosed with laser-induced maculopathy between September …

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Minimally invasive PVR surgery-MIPS

Giriraj Vibhute, Shrinivas M Joshi, Apoorva Ayachit, Guruprasad S. Ayachit

Background: Proliferative vitreoretinopathy (PVR) is one of the main reasons for recurrent retinal detachments, usually requiring multiple re-surgeries. This technique of minimally invasive PVR surgery (MIPS) provides a simpler and cost-effective way of treating PVR in selected cases. Purpose: To demonstrate the …

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Programme for ocular inflammation & infection translational research (PROTON) registry: Cross-sectional analysis of baseline patient characteristics

William Andrés Rojas-Carabali, Kevin K. F. Chan, Carlos Cifuentes‐González, Alok C. Sen et autres

PURPOSE: The Programme for Ocular Inflammation & Infection Translational Research (PROTON) registry collects real-world data on infectious and non-infectious ocular inflammatory diseases (OID) to enhance understanding of disease progression and treatment outcomes. This report presents the baseline characteristics of patients enrolled in …

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Diabetic vitrectomy: Finding the sweet spot – A learning experience

Giriraj Vibhute, Shrinivas M Joshi, Apoorva Ayachit, Guruprasad S. Ayachit

Background: New surgeons/fellows always struggle to handle diabetic vitrectomies, and this video tries to briefly explain with demonstrations and simple analogies the basics of the same. Purpose: To demonstrate maneuvers, procedures, and some tips to help students learn the basics of diabetic …

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Safety and efficacy of frequency-doubled Nd-YAG laser photocoagulation of different types of corneal neovascularisation (NLPC): a prospective study

Keerti Gururaj Wali, Shilpa Maled, Ronak Solanki, Apoorva Ayachit et autres

PURPOSE: Frequency doubling of neodymium-doped yttrium aluminum garnet (Nd-YAG) laser results in emission of photocoagulating 532 nm light compared with photolytic 1064 nm emission. The ergonomic benefits of solid-state lasers led to replacement of older coagulating lasers in ophthalmic centres by frequency-doubled …

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Geographical differences in ophthalmic trauma outcomes and risk factors: the International Globe and Adnexal Trauma Epidemiological Eye Study (IGATES)

Annette K. Hoskin, Sean Ng Ming Sheng, Richard James Blanch, Giridhar Anantharaman et autres

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Geographical Differences in Ophthalmic Trauma Outcomes and Risk Factors: The International Globe and Adnexal Trauma Epidemiological Eye Study (IGATES)

Annette K. Hoskin, Sean Ming Sheng Ng, Richard James Blanch, Giridhar Anantharaman et autres

Abstract Objectives: characterize the international variation in ophthalmic trauma and validate prognostic markers for low-, middle- and high income countries. Subjects/Methods:.Observational Multicentre cohort study using International Globe and Adnexal Trauma Epidemiological Eye Study (IGATES) to collect data on acute presentations with ophthalmic …

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