Robert Diep

First, do NOHARM: towards clinically safe large language models.

David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain et autres

Large language models (LLMs) are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized. We present NOHARM (Numerous Options Harm Assessment for Risk in Medicine), a benchmark using 100 real primary care-to-specialist consultation cases …

First, do NOHARM: a medical safety benchmark and randomized study of physician and AI teaming on clinical consultations

David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Jessica Tran et autres

Large language models (LLMs) and medical AI tools are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized. We present NOHARM (Numerous Options Harm Assessment for Risk in Medicine), a 1,100-task benchmark of primary …

MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis

Vishesh Khanna, Gohar Eslami, Rochelle Reyes, Robert Diep et autres

Murine double minute 2 (MDM2) inhibitors have shown promising activity in TP53-wild type tumors and are under active investigation across a spectrum of malignancies. Herein, we report a 51-year-old female with MDM2-amplified, TP53-wild type adenoid cystic carcinoma who was treated with a …

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Reduced versus full apixaban lead-in dosing following parenteral treatment of acute venous thromboembolism

Daniella Veloria, Benjamin Wang, Ran Ran, David Ha et autres

MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis

Vishesh Khanna, Gohar Eslami, Rochelle Reyes, Robert Diep et autres

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Cancer-Associated Venous Thromboembolic Disease, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology

Michael B. Streiff, Bjorn Holmstrom, Dana E. Angelini, Aneel A. Ashrani et autres

The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease provide strategies for the prevention, diagnosis, and treatment of venous thromboembolism (VTE) in adult patients with cancer. VTE is a common and life-threatening condition in patients with cancer, and its management often requires multidisciplinary …

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P2.31-02 Real-World Survival Outcomes in NSCLC in Adults Ages 50 and Younger at a Large Academic Institution

Robert Hsu, Darin Poei, M. Macdonald, Robert Diep et autres

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In COVID-19, therapeutic vs. prophylactic anticoagulation did not improve clinical outcomes and increased bleeding

Robert Diep, David García

SOURCE CITATION: Lancet. 2021;397:2253-63. 34097856.

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Does aspirin prevent venous thromboembolism?

Robert Diep, David García

Venous thromboembolism (VTE; deep vein thrombosis and/or pulmonary embolism) is a well-established cause of morbidity and mortality in the medical and surgical patient populations. Clinical research in the prevention and treatment of VTE has been a dynamic field of study, with investigations …

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Should we monitor the direct oral anticoagulants?

Robert Diep, David García

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A novel nucleotide substitution in the 5′ untranslated region of ANKRD26 gene is associated with inherited thrombocytopenia: a report of two new families

Robert Diep, Kristin Corey, Murat O. Arcasoy

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A rare CALR variant mutation and a review of CALR in essential thrombocythemia

Robert Diep, Ara Metjian

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