Annemiek Dols

A Shift in Trust: An Analysis of the Use of AI Chatbots Among People Living With Bipolar Disorder

Katherine C. Bassil, Suzanne Prins, Hine van Os, Georg Starke et autres

OBJECTIVES: To identify preliminary insights into the perceived utility and risks of commercially available AI chatbots such as ChatGPT used by individuals with severe mental illness (SMI), namely bipolar disorder, for self-reflection and mental health support. METHODS: Data were collected via semi-structured …

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The Association Between Lithium Use and Physical Comorbidities Across Age Groups: A Cross‐Sectional Study From the Global Aging and Geriatric Experiments in Bipolar Disorder ( GAGE ‐ BD ) Project

Ni Xu, Orestes Vicente Forlenza, Peijun Chen, Soham Rej et autres

ABSTRACT Introductions Lithium remains the first‐line maintenance treatment for bipolar disorder (BD), yet its safety in older‐age BD (OABD) is uncertain due to limited large‐scale data. OABD patients often experience more severe physical comorbidities compared to younger BD patients, but systematic evidence …

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Cortical Thickness in Middle and Older Aged Adults With Bipolar Disorder Across Six International Sites

Rebecca B. Marks, Anjali Sankar, Lejla Čolić, Jair Soares et autres

ABSTRACT Background Older adults with bipolar disorder ( BD ) are at high risk for severe mood symptoms, cognitive difficulties, and early mortality; however, underlying brain alterations have received little study. Gray matter decreases in ventral prefrontal cortex ( VPFC ) seen …

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Towards a Safe and Effective Lithium Therapeutic Range for Older Adults With Bipolar Disorder: An ISBD Task Force Systematic Review

Paula Villela Nunes, Andrew T Olagunju, Debbie Zittema, Astha Dhyani et autres

OBJECTIVES: Lithium is recommended as the first-line maintenance treatment for older adults with bipolar disorder (OABD). However, age-related reduction in renal clearance, heightened sensitivity to adverse effects, and drug interactions increase the risk of toxicity and necessitate lower therapeutic serum levels in …

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Biofluid Biomarkers of Cognitive Functioning in Bipolar Disorder: A Systematic Review by the Targeting Cognition and Older‐Age Bipolar Disorder ISBD Task Forces

Alexandra J.M. Beunders, Sigfried N. T. M. Schouws, Andrew T Olagunju, Vicent Balanzá‐Martínez et autres

BACKGROUND: Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently …

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Author Correction: Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects

Olga Therese Ousdal, Miklós Árgyelán, Maarten Laroy, Amit N. Anand et autres

In the version of the article initially published, the first name of Maximilian Kiebs was misspelled (Maximillian), and is now amended in the HTML and PDF versions of the article.

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Systematic review on relapse-prevention strategies following successful electroconvulsive therapy for major depressive disorder

Jordy J. E. Rovers, Nander van Zeijl, Indira Tendolkar, Annemiek Dols et autres

BACKGROUND: Electroconvulsive therapy (ECT) is highly effective for major depressive disorder (MDD), but about 50% of patients relapse within 1 year. A comprehensive review of all potential relapse-prevention strategies is lacking. AIMS: This systematic review aimed to identify, summarise and critically evaluate …

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Variation in Public Health Reimbursement Policies of ECT and rTMS Across 28 European Countries: A Call for Evidence-Based Policy Reform from the ECNP Neuromodulation Network

Nils Opel, Jovana Bjekić, Jerome Brunelin, Jean-Marie V. Batail et autres

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Executive Function Among Older Adults With Bipolar Disorder: A GAGE-BD Analysis

Federica Klaus, Erin Appiah, Izabela Guimarães Barbosa, Peijun Chen et autres

OBJECTIVES: Executive function deficits in bipolar disorder (BD) are major contributors to disability in older age BD (OABD). We investigated the difference between OABD and age-equated healthy comparators (HC); and, in the OABD group, the associations of executive function with age, symptom …

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Patients With Older-Age Bipolar Disorder (OABD) Visiting a Memory Clinic: Differentiating Underlying Pathophysiology With MRI and Cerebrospinal Fluid Markers

Alexandra J.M. Beunders, Everard G.B. Vijverberg, Charlotte Elisabeth Teunissen, Sigfried N. T. M. Schouws et autres

Background Many patients with bipolar disorder (BD) report cognitive problems. Pathophysiology of cognitive impairment in BD is unclear, although prevalence of dementia in BD is high. In Older-Age Bipolar Disorder (OABD) patients with cognitive complaints, neurodegeneration may play a role. This could …

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Antidepressant use in older age bipolar disorder (OABD): Results from the GAGE-BD international consortium

Christina Rigas, Paola Lavín, Peijun Chen, Susana Gabriela Torres-Platas et autres

BACKGROUND: Antidepressants are still commonly prescribed in bipolar disorders, despite ongoing controversy of the potential risk of inducing hypomania/mania. There is limited knowledge about the characteristics of antidepressant use in older age bipolar disorder (OABD; age ≥50) in the current literature. AIM: …

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Insights Into Electroconvulsive Therapy for Depression

Dore Loef, Philip van Eijndhoven, Esmée Verwijk, Birit F. P. Broekman et autres

kein CA

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