Slobodan Paessler

Lassa fever and Argentine hemorrhagic fever treatment in guinea pigs using broad-spectrum cap-dependent endonuclease inhibitors

Junki Maruyama, Satoshi Taniguchi, Takeshi Saito, Shintaro Yamada et autres

encompasses several highly pathogenic viruses that cause lethal hemorrhagic fevers. Due to their limited prevention and treatment options and high pathogenicity, these viruses require handling in biosafety level-4 facilities. Within the bunyaviruses, arenaviruses are particularly notable for their pathogenicity and ability to …

ca, us, jp, fr (code pays fourni par la source)

Dataset 3

Slobodan Paessler, Veljko Veljković

Flu epidemics and potential pandemics pose great challenges to public health institutions, scientists and vaccine producers. Creating right vaccine composition for different parts of the world is not trivial and has been historically very problematic. This often resulted in decrease in vaccinations …

us (code pays fourni par la source)

Dataset 2

Slobodan Paessler, Veljko Veljković

Flu epidemics and potential pandemics pose great challenges to public health institutions, scientists and vaccine producers. Creating right vaccine composition for different parts of the world is not trivial and has been historically very problematic. This often resulted in decrease in vaccinations …

us (code pays fourni par la source)

Human H3N2 influenza viruses collected in the United States from January to February 2018 (GISAID EpiFluTM database, accessed February 20, 2018)

Slobodan Paessler, Veljko Veljković

Flu epidemics and potential pandemics pose great challenges to public health institutions, scientists and vaccine producers. Creating right vaccine composition for different parts of the world is not trivial and has been historically very problematic. This often resulted in decrease in vaccinations …

us (code pays fourni par la source)

The AQVN and EIIP 42 ingredients of the liquid diet Fresubin.

Veljko Veljković, Vladimir Perović, Marko Anderluh, Slobodan Paessler et autres

Background: Healthy nutrition is vital for good health and well-being. Despite the important role of a healthy nutritional diet, recommendations for healthy eating remain elusive and are mainly based on general properties of nutrients. The present study proposes an improved characterization of …

us, si (code pays fourni par la source)

The AQVN and EIIP of 227 commonly used organic nutrients collected from various sources.

Veljko Veljković, Vladimir Perović, Marko Anderluh, Slobodan Paessler et autres

Background: Healthy nutrition is vital for good health and well-being. Despite the important role of a healthy nutritional diet, recommendations for healthy eating remain elusive and are mainly based on general properties of nutrients. The present study proposes an improved characterization of …

us, si (code pays fourni par la source)

The AQVN and EIIP of 126 organic nutrients from human milk collected from various sources.

Veljko Veljković, Vladimir Perović, Marko Anderluh, Slobodan Paessler et autres

Background: Healthy nutrition is vital for good health and well-being. Despite the important role of a healthy nutritional diet, recommendations for healthy eating remain elusive and are mainly based on general properties of nutrients. The present study proposes an improved characterization of …

us, si (code pays fourni par la source)

Differential olfactory dysfunction and nasal tissue pathology in Syrian hamsters infected with SARS-CoV-2 variants

Takeshi Saito, Marina Hosotani Saito, Rachel A. Reyna, Satoshi Taniguchi et autres

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the global coronavirus disease 2019 (COVID-19) pandemic, frequently induces olfactory dysfunction (OD), a symptom that significantly impacts patients' quality of life. Understanding the variability in OD and nasal tissue pathology across different …

us (code pays fourni par la source)

Discovery of potent cross-neutralizing antibodies for the treatment of Marburg virus disease

Ayato Takada, Takeshi Saito, Hiroko Miyamoto, Manabu Igarashi et autres

jp, us (code pays fourni par la source)

Influenza a Virus Inhibition: Evaluating Computationally Identified Cyproheptadine Through In Vitro Assessment

Sanja Glišić, Kristina Stevanović, Andrej Perdih, Natalya Bukreyeva et autres

Influenza is still a chronic global health threat, inducing a sustained search for effective antiviral therapeutics. Computational methods have played a pivotal role in developing small molecule therapeutics. In this study, we applied a combined in silico and in vitro approach to …

rs, si, us, es, it (code pays fourni par la source)

Identification of Factors Contributing to Pathogenic Variability Among Lassa Virus Strains Using the Guinea Pig Model and Reverse Genetics

Satoshi Taniguchi, Takeshi Saito, Ruchi Paroha, Cheng Huang et autres

Lassa virus (LASV) is the causative agent of Lassa fever (LF), a severe hemorrhagic disease with potential for lethal outcomes. Classified as a risk group 4 pathogen, it represents a significant public health threat in endemic regions. Our laboratory previously developed a …

jp, us (code pays fourni par la source)

The Eye of the Chiropterologist: Phenotypic Versus Genotypic Identification of Bats

Filibus Danjuma Dami, Adeniyi T. Adeyanju, Adams A. Chaskda, I. M. Okpanachi et autres

ABSTRACT Bats are a diverse and ecologically important group of mammals that play critical roles in ecosystems. Accurate identification is necessary to comprehend bat species' ecology and behavior to further the conservation of bats. Both phenotypic and genotypic methods have been used …

Nigéria, us (code pays fourni par la source)