Accès ouvert
2025
article
OpenAlex
Takeshi Saito, Marina Hosotani Saito, Rachel A. Reyna, Satoshi Taniguchi et autres
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the global coronavirus disease 2019 (COVID-19) pandemic, frequently induces olfactory dysfunction (OD), a symptom that significantly impacts patients' quality of life. Understanding the variability in OD and nasal tissue pathology across different …
us
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Accès ouvert
2025
article
OpenAlex
Masaki Fujimoto, Tomohito Iwasaki, Marina Hosotani Saito, Naoki Takahashi et autres
Emerging evidence indicates that oxidative stress in skeletal muscle is a prerequisite for sarcopenia in diabetic patients. In this study, we show that ubiquitin-specific protease (USP) 2 mitigates the accumulation of reactive oxygen species (ROS) in mature muscle cells. Treatment with ML364, …
jp, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Erika Tsuji, Kanako Sumi, Natsuko Tsuzuki, Daisuke Kondoh et autres
Histological staining is essential for understanding bone structure and pathology; however, variations in decalcification agents can compromise reproducibility. We have previously developed a novel osteochondral staining method, Join of the Five dyes Revealing coLlagenous tissue (JFRL) staining, that is independent of the …
jp
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
John M Coggins, Marina Hosotani Saito, Rebecca S. Cook, Shinji Urata et autres
OBJECTIVE: With altered sense of taste being a common symptom of coronavirus disease 2019 (COVID-19), the main objective was to investigate the presence and distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) within the tongue over the course of infection. METHODS: Golden …
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Tetsu SUZUKI, Marina Hosotani Saito, Nantian Lin, Atsushi Tamura et autres
Lassa fever (LF), caused by Lassa virus (LASV) infection, typically leads to mild symptoms in humans, but some survivors experience audiovestibular problems. Here we present vestibular histopathological insights in our LF model mice. We observed (1) hemorrhage within the vestibular ganglion and …
us
(code pays fourni par la source)