Kosuke Takano

Whole exome sequencing analysis of a patient with myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions with ETV6::LYN fusion gene

Rika Hosoba, Suguru Fukuhara, Yasunori Kogure, Kosuke Takano et autres

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Low urinary sodium-to-potassium ratio in the early phase following single-unit cord blood transplantation is a predictive factor for poor non-relapse mortality in adults

Kosuke Takano, Maki Monna‐Oiwa, Masamichi Isobe, Seiko Kato et autres

Although daily higher urinary sodium (Na) and potassium (K) excretion ratio is associated with the risk of cardiovascular disease in the general population, a low Na/K ratio is associated with renal dysfunction in critically ill patients. Thus, we retrospectively analyzed the impact …

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Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults

Takaaki Konuma, Kosuke Takano, Maki Monna‐Oiwa, Masamichi Isobe et autres

Augmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by …

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Prognostic impact of switching from cyclosporine to corticosteroids early after single cord blood transplantation

Kosuke Takano, Maki Monna‐Oiwa, Masamichi Isobe, Seiko Kato et autres

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[Successful treatment of secondary graft failure after allogeneic stem cell transplantation for aplastic anemia with eltrombopag].

Kosuke Takano, Takuya Izumi, Toshikuni Kawamura, Toshikatsu Horiuchi et autres

Herein we report a case of successful treatment of secondary graft failure due to poor graft function (PGF) using eltrombopag. A 25-year-old woman with aplastic anemia (stage 3) underwent allogeneic bone marrow transplantation (BMT) from her HLA-matched brother. Neutrophil engraftment was achieved …

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Optimal time and threshold of absolute lymphocyte count recovery as a prognostic factor after single‐unit cord blood transplantation in adults

Takaaki Konuma, Maki Monna‐Oiwa, Kosuke Takano, Masamichi Isobe et autres

Abstract We retrospectively evaluated the optimal time and threshold of absolute lymphocyte count (ALC) recovery as a prognostic factor in 174 adult patients who received single‐unit cord blood transplantation (CBT) at our institute. We analyzed the impact of ALC ≥300, ≥600, and …

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[Bendamustine and rituximab combination therapy for recurrent indolent B-cell lymphomas: a retrospective single-institution study].

Masahiro Teramoto, Takehiro Sone, Kohei Takada, Hiraku Ogata et autres

This retrospective study evaluated the outcomes of patients treated with combination of bendamustine and rituximab (BR) for recurrent indolent B-cell lymphoma from January 2011 to February 2018 in our department. The cohort included 36 males and 27 females, and majority of the …

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Sudden blast phase in chronic myeloid leukemia developed during nilotinib therapy after major molecular response was achieved

Yosuke Okada, Ken Sato, Shinichi Kobayashi, Shigeki Nagao et autres

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