Accès ouvert
2022
article
OpenAlex
Kashif Iqbal Sahibzada, Lilia Ganova‐Raeva, Zoya Dimitrova, Sumathi Ramachandran et autres
Hepatitis C virus (HCV) infections are public health problem across the globe, particularly in developing countries. Pakistan has the second highest prevalence of HCV infection worldwide. Limited data exist from Pakistan about persons who inject drugs (PWID) and are at significant risk …
us, pk
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Accès ouvert
2022
article
OpenAlex
J. Walker Gussler, David S. Campo, Zoya Dimitrova, Pavel Skums et autres
BACKGROUND: Investigation of outbreaks to identify the primary case is crucial for the interruption and prevention of transmission of infectious diseases. These individuals may have a higher risk of participating in near future transmission events when compared to the other patients in …
us
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Accès ouvert
2021
article
OpenAlex
Sumathi Ramachandran, Guoliang Xia, Zoya Dimitrova, Yu‐Lin Lin et autres
Hepatitis A virus (HAV) genotype IA was most common among strains tested in US outbreak investigations and surveillance during 1996-2015. However, HAV genotype IB gained prominence during 2016-2019 person-to-person multistate outbreaks. Detection of previously uncommon strains highlights the changing molecular epidemiology of …
us
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Accès ouvert
2020
preprint
OpenAlex
J. Walker Gussler, David S. Campo, Zoya Dimitrova, Pavel Skums et autres
Abstract Investigation of outbreaks to identify the primary case is crucial for the interruption and prevention of transmission of infectious diseases. These individuals may have a higher risk of participating in near future transmission events when compared to the other patients in …
us
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
Lilia Ganova‐Raeva, Zoya Dimitrova, Ivailo Alexiev, Lili Punkova et autres
BACKGROUND: The rate of HIV infection in Bulgaria is low. However, the rate of HCV-HIV-coinfection and HCV infection is high, especially among high-risk communities. The molecular epidemiology of those infections has not been studied before. METHODS: Consensus Sanger sequences of HVR1 and …
us, bg
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Accès ouvert
2018
article
OpenAlex
Sumathi Ramachandran, Hong Thai, Joseph C. Forbi, Zoya Dimitrova et autres
BACKGROUND: A high prevalence (92.3%) of hepatitis C virus (HCV) co-infection among HIV patients identified during a large HIV outbreak associated with injection of oxymorphone in Indiana prompted genetic analysis of HCV strains. METHODS: Molecular epidemiological analysis of HCV-positive samples included genotyping, …
us
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Accès ouvert
2018
preprint
OpenAlex
Sumathi Ramachandran, Hong Thai, Joseph C. Forbi, Zoya Dimitrova et autres
us
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Accès ouvert
2017
article
OpenAlex
Atkinson G. Longmire, Seth Sims, Inna Rytsareva, David S. Campo et autres
BACKGROUND: Hepatitis C is a major public health problem in the United States and worldwide. Outbreaks of hepatitis C virus (HCV) infections associated with unsafe injection practices, drug diversion, and other exposures to blood are difficult to detect and investigate. Effective HCV …
us
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Accès ouvert
2017
article
OpenAlex
Pavel Skums, Alex Zelikovsky, Rahul Singh, Walker Gussler et autres
Motivation: Genomic analysis has become one of the major tools for disease outbreak investigations. However, existing computational frameworks for inference of transmission history from viral genomic data often do not consider intra-host diversity of pathogens and heavily rely on additional epidemiological data, …
us
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2017
article
OpenAlex
Alexandra Tejada‐Strop, María Isabel Costafreda, Zoya Dimitrova, Gerardo Kaplan et autres
us
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Accès ouvert
2017
article
OpenAlex
Brendan Palmer, Zoya Dimitrova, Pavel Skums, Órla Crosbie et autres
, 2014 ). Initial clonal analysis of serum samples was used to inform downstream error correction algorithms that allowed for a greater sequence depth to be reached. PCR amplification of this region has been tested for HCV genotypes 1, 2, 3 and …
ie, us
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2016
other
OpenAlex
Pavel Skums, Alexander Artyomenko, Olga Glebova, Sumathi Ramachandran et autres
This chapter considers the problem of pooling design for massive viral data. It formulates the pool design problem as an optimization problem on graphs, and describes heuristic algorithms to solve them. The chapter reviews the method for deconvolution of individual samples from …
us
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