Guangdong Chen

Surface chemistry of talc and nanotalc enables interface-mediated hydrolytic degradation of poly(L-lactide)

Yang Li, Dai-Wu Deng, Zi-Xuan Zhang, Guangdong Chen et autres

Aircraft attitude tracking method based on reference to the wave structure

Zhuhang Liu, Guangdong Chen, Bingqi Liu, Minzhe Luo

A digital twin-based method for predicting the burst speed of discs

Guangdong Chen, Gang Wei, Shengli Xu, Haixin Zhao et autres

Overspeed burst is a critical failure mode of discs, for which experimental validation is costly and destructive, while conventional finite element analysis (FEA) is computationally expensive and often inaccurate. To address these challenges, this study proposes a digital twin-based method for disc …

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Moderating effects of affective interventions on manic symptoms and quality of life: A cognitive improvement study based on patients with bipolar disorder

Bingwei Zhang, Suilin Jia, Guangdong Chen

BACKGROUND: Initially, psychotherapy was the primary treatment for bipolar disorder. However, with advances in biomedical research and the rapid efficacy of medications, psychosocial treatments have been increasingly overlooked. Despite evidence supporting bipolar disorder as a "biological disease," psychotherapy remains essential as an …

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Molecular mechanisms of olanzapine against agitation in schizophrenia and bipolar disorder based on network pharmacology and molecular docking

Xuemin Shi, Xingying Chen, Xiaoyan Ma, Ranli Li et autres

Olanzapine, a second-generation antipsychotic, is commonly used to manage agitation in patients with schizophrenia and bipolar disorder, though its underlying mechanism of action remains unclear. In this study, network pharmacology and molecular docking were applied to explore the potential molecular mechanisms of …

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Stability characteristics of medial meniscus tear in mild varus knee: a finite element analysis

Chunxiao Yu, Wenjun Zhao, Kexin Liu, Xiao-Kang Gao et autres

BACKGROUND: Recent studies have pointed out that varus alignment is a potential risk factor for medial overload and the development of osteoarthritis, which may influence the healing of meniscus tears. This study aimed to analyze the stress distribution of radial and longitudinal …

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Application of 3D-Printed Artificial Vertebrae in the Reconstruction After Resection of Complex Malignant Spinal Tumors

Jingtao Ji, Guangdong Chen, Jun Miao

STUDY DESIGN: The reconstruction of the anterior vertebral body using 3D-printed artificial vertebrae after total en bloc spondylectomy for spinal tumors restores spinal stability. OBJECTIVE: To investigate the feasibility of using 3D-printed artificial vertebrae for spinal reconstruction after tumor resection. SUMMARY OF …

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Attitude Estimation for Spacecraft Docking Based on EMVS Array via PARAFAC Algorithm

Bingqi Liu, Guangdong Chen, Liu Zhuhang, Song He

A spacecraft attitude estimation method based on electromagnetic vector sensors (EMVS) array is proposed, which employs the orthogonally constrained parallel factor (PARAFAC) algorithm and makes use of measurements of the two-dimensional direction-of-arrival (2D-DOA) and polarization angles, aiming to address the issues of …

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Physicochemical Properties and Biocompatibility of Injectable Hydroxyapatite Cement and Its Application in Compressive Tibial Plateau Fractures

Xiang Sun, Guangdong Chen, Yang Chen, Zepei Zhang et autres

Injectable carbonated hydroxyapatite (ICHA) cement was developed by adding 2% Hydroxypropyl methylcellulose (HPMC) to carbonated hydroxyapatite (CHA) cement, improving its rheological properties and injectability for minimally invasive orthopedic use. The cement's physical and chemical properties, including curing time, strength, porosity, and consistency, …

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IL-17A exacerbates synovial inflammation in osteoarthritis via activation of endoplasmic reticulum stress

Wen Sun, Xueyan Li, Liyuan Zhang, Yuheng Zhang et autres

The primary clinical manifestations of osteoarthritis (OA) are joint pain and restricted movement capabilities. Synovial inflammation, serving as an initiator of OA progression, intensifies cartilage damage via the generation of various deleterious agents, including pro-inflammatory cytokines and nociceptive mediators. Despite extensive research …

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Prediction of carbonate permeability from multi-resolution CT scans and deep learning

Lin Zhang, Guangdong Chen, Jing Ba, José Maria Carcione et autres

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Preliminary Application of 3D-Printed Interbody Fusion Devices in the Treatment of Lumbar Degenerative Diseases

Jingtao Ji, Guangdong Chen, Jun Miao

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