Xian Shen

Sequential computed tomography angiography and computed tomography enterography suggesting an inverted Meckel’s diverticulum in recurrent gastrointestinal bleeding: A case report

Linxi Lv, Xinxin Yang, Junyu Ying, Xiaoke Wu et autres

A global digital navigator of human health for precision medicine

Kang Zhang, Jiahong Dong, Hang Wong, Sian Liu et autres

mo, cn, us, gb, fr, sg (code pays fourni par la source)

Retraction Note: An autocatalytic multicomponent DNAzyme nanomachine for tumor-specific photothermal therapy sensitization in pancreatic cancer

Jiaqi Yan, Xiaodong Ma, Danna Liang, Meixin Ran et autres

The authors have retracted this article. After publication, the authors identified the following errors in the figures: Fig. 8a duplicated 24 h and 48 h images; Figure 8g, 9c, and 9g image errors and mislabelling; Figure 8h and 9d incorrect data in …

fi, cn (code pays fourni par la source)

Risk factors and prediction model of renal dysfunction in patients with inflammatory bowel disease: a retrospective cohort study

Yide Zhou, Kefang Sun, Xia Chen, Xian Shen et autres

Previous studies have identified the association between inflammatory bowel disease (IBD) and its renal complications, but specific risk factors and predictive models remain underexplored. To identify the risk factors for renal dysfunction in IBD patients and to develop a clinical model for …

cn, us, cz (code pays fourni par la source)

Otopetrin 1 protects against adipose tissue wasting during cancer cachexia progression

Danjie Li, Yan Xialin, Wenbo Zhai, Chenhao He et autres

expression in subcutaneous WAT was reduced in cachexia and positively correlated with BMI in cachectic patients. In adipocytes treated with tumor-conditioned medium, OTOP1 overexpression alleviated metabolic dysfunction, accompanied by suppression of NF-κB signaling and activation of PPARγ, leading to reduced lipolysis and …

cn (code pays fourni par la source)

Phytochemicals in Food and Medicine : Advancing Translational Science at the Interface of Nutrition and Health

Tarun Belwal, Francesco Epifano, Deep Jyoti Bhuyan, Evelyn Wolfram et autres

us, it, au, ch, cn (code pays fourni par la source)

Safety and feasibility of novel single-port robotic systems in colorectal cancer surgery: a comparative study with the da Vinci Xi system

Jingwei Zheng, Dongze Wu, Xinxin Yang, Zhixuan Jiang et autres

PURPOSE: To compare perioperative outcomes and safety between the novel single-port robotic systems (SPRS) and the da Vinci Xi robotic system (DVRS) in radical colorectal cancer resection. METHODS: In this retrospective cohort study, 59 patients who underwent curative colorectal resection were assigned …

cn (code pays fourni par la source)

Natural origin microfiber scaffolds from microfluidic spinning for gastric tumor postsurgical treatment

Jiante Li, Hongzheng Li, Yiwei Jiang, Shangrui Rao et autres

The PMs@HCS scaffold was designed to eliminate residual cancer and promote gastric repair. • A Huachansu-loaded Premna Microphylla microfiber scaffold was fabricated by microfluidic spinning. • The scaffold effectively inhibits tumor recurrence and improves survival in gastric cancer models. • The bioactive …

cn, fi (code pays fourni par la source)

A Sono‐Responsive Nanoplatform Integrating STING Activation and CXCR4 Blockade for Synergistic Immunotherapy of Glioblastoma

Xiaoying Kang, Wenwen Chen, Yuan Zhang, Jingyi Ma et autres

Glioblastoma (GBM), an aggressive brain tumor with a highly immunosuppressive microenvironment, remains a therapeutic challenge due to its resistance to conventional treatments. In this study, a novel multi-function therapeutic platform that integrates ultrasound-triggered sonodynamic therapy (SDT), STING pathway activation, and CXCR4 inhibition …

cn (code pays fourni par la source)

Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

Xiaojia Li, Wei Fang, Tingting Jiang, Lu Zhang et autres

We discovered that Plakophilin 3 (PKP3) was expressed only at the apical membrane of duct cells in the pancreas, and its expression was induced in acinar-to-ductal metaplasia (ADM), pancreatic intraepithelial neoplasia (PanIN), and pancreatic ductal adenocarcinoma (PDAC) cells. PKP3 was predominantly localized …

cn (code pays fourni par la source)

A full life cycle biological clock based on routine clinical data and its impact in health and diseases

Kai Wang, Fei Liu, Wei Wu, Changxi Hu et autres

Aging research has primarily focused on adult aging clocks, leaving a critical gap in understanding a biological clock across the full life cycle, particularly during infancy and childhood. Here we introduce LifeClock, a biological clock model that predicts biological age across all …

cn, us, mo, au, fr (code pays fourni par la source)

Multi-regional feature integration on enhanced CT for lymph node metastasis prediction in gastric cancer: a novel radiomics approach

Huaiqing Zhi, Dongze Wu, Wanda Cai, Chenbin Chen et autres

BACKGROUND: Lymph node metastasis (LNM) represents the predominant metastatic pathway and a critical prognostic determinant in gastric adenocarcinoma. Accurate preoperative prediction of LNM status is imperative for optimizing tumor staging, therapeutic decision-making, and prognostic evaluation. This study aims to develop and validate …

cn (code pays fourni par la source)