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Paola Manzo, Anna Lisa Cammarota, Jelena Dimitrov, Antonia Falco et autres
Previous studies identified BAG3 as a stress-induced protein with pro-survival functions in various tumors. Based on this assumption, we analyzed the expression and secretion of BAG3 in 24 cancer cell lines representing ten types of cancer and compared these results with samples …
it (code pays fourni par la source)
Maurizio Maddalena, Jelena Dimitrov, Tayyaba Mehmood, Cristina Terlizzi et autres
Neutrophil extracellular traps (NETs) are complex structures released by activated neutrophils and composed by double-stranded DNA associated with histones and an arsenal of proteases and proteins. NETs are reported to be present in tumors and blood of cancer patients where they can …
it (code pays fourni par la source)
Anna Donniacuo, Antonio Di Mauro, Chiara Cardamone, Anna Maria Basile et autres
Autoimmune diseases are characterized by dysregulated adaptive immune responses leading to chronic inflammation and tissue damage. Cytokines and growth factors play central roles in modulating immune regulation, inflammation, and tissue repair, thereby representing critical biomarkers for the enhancement of diagnosis, prognosis, and …
it (code pays fourni par la source)
Anna Donniacuo, Antonio Di Mauro, Chiara Cardamone, Anna Maria Basile et autres
Autoimmune diseases are characterized by dysregulated adaptive immune responses leading to chronic inflammation and tissue damage. Cytokines and growth factors play central roles in modulating immune regulation, inflammation, and tissue repair, thereby representing critical biomarkers for the enhancement of diagnosis, prognosis, and …
it (code pays fourni par la source)
Pietro De Luca, Francesco Antonio Salzano, Angelo Camaioni, Leopoldo Costarelli et autres
Background: Head and neck squamous cell carcinoma (HNSCC) exhibit considerable heterogeneity, complicating the prediction of disease progression and treatment response. Consequently, researchers are actively investigating reliable biomarkers to forecast disease trajectories and inform therapeutic decisions. This study examines the role of BAG3, …
it (code pays fourni par la source)
Jelena Dimitrov, Maurizio Maddalena, Cristina Terlizzi, Giovanna Giuseppina Altobelli et autres
Introduction: Neutrophil extracellular traps (NETs) are complex structures released by activated neutrophils that may modulate different steps of the metastatic cascade. The aim of our study was to investigate how NETs can modulate the adhesion properties of cancer cells and whether cell …
it (code pays fourni par la source)
Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli, Antonio Pezone et autres
BACKGROUND: ATM is a multifunctional serine/threonine kinase that in addition to its well-established role in DNA repair mechanisms is involved in a number of signaling pathways including regulation of oxidative stress response and metabolic diversion of glucose through the pentose phosphate pathway. …
it (code pays fourni par la source)
Milan M. Obradovic, Sonja S. Zafirovic, Magbubah Essack, Jelena Dimitrov et autres
To remedy carotid artery stenosis and prevent stroke surgical intervention is commonly used, and the gold standard being carotid endarterectomy (CEA). During CEA cerebrovascular hemoglobin oxygen saturation decreases and when this decrease reaches critical levels it leads to cerebral hypoxia that causes …
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