Victoria Banuchi

Scholarly Dialogue on Risk to the Recurrent Laryngeal Nerve with Thermal Ablation Procedures: A Reflection on Empirical Practices

Marika D. Russell, Che‐Wei Wu, Tzu‐Yen Huang, Robert Michael Tuttle et autres

Background: Radiofrequency and other ablative treatments for thyroid nodules and thyroid malignancies are increasingly being adopted into clinical practice. The safety of these procedures with respect to the recurrent laryngeal nerve (RLN) is not well-characterized. Summary: Our current understanding of RLN injury …

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Segmental Tracheal Resection for Thyroid Cancer: Perioperative Morbidity, Locoregional Control, and Survival

Anastasios Maniakas, David Chamberlayne Wilde, Isabelle Fournier, Xu Li et autres

BACKGROUND: Segmental tracheal resection is rarely needed for advanced thyroid cancer but is among the most complex, high-risk thyroid surgeries. METHODS: Retrospective study of patients undergoing segmental tracheal resection for thyroid cancer at MD Anderson Cancer Center (2005-2024). RESULTS: We identified 120 …

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Management of Retropharyngeal Lymph Node Metastases in Thyroid Cancer

Isabelle Fournier, A. Bandi, Sarah Hamidi, Priyanka Chandrasekhar Iyer et autres

BACKGROUND: Retropharyngeal lymph node (RPLN) metastases in thyroid cancer are rare, with optimal management underreported. METHODS: Retrospective study of consecutive thyroid cancer patients with RPLN metastases treated at MD Anderson Cancer Center between 2000 and 2024. RESULTS: One hundred and sixty-seven patients …

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Partial Laryngectomy for Thyroid Cancer: A Single Institution Case Series With Operative Techniques

Ella E. Hawes, Victoria Banuchi, Anastasios Maniakas, Jennifer Rui Wang et autres

BACKGROUND: Partial laryngectomy has been well described as a management option for T1-3 laryngeal squamous cell cancers. However, there are a few case reports of partial laryngeal surgery for locally advanced thyroid carcinoma. METHODS: This is a case series of five patients …

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Characterization of Advanced RAS -driven Follicular-derived Thyroid Cancers and Review of Future Therapeutic Avenues

Sarah Hamidi, Anastasios Maniakas, Neal S. Akhave, Victoria Banuchi et autres

CONTEXT: With novel RAS-targeted therapies emerging, better understanding of RAS-driven differentiated (DTC) and anaplastic (ATC) thyroid cancers is warranted. OBJECTIVE: Characterize the genotypic and phenotypic landscape of RAS-driven DTC and ATC and review current and future therapeutic avenues. DESIGN: Retrospective chart review …

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Circulating Tumor DNA as a Biomarker for Disease Surveillance in Anaplastic Thyroid Cancer

Sarah Hamidi, Ramona Dadu, Priyanka Chandrasekhar Iyer, Naifa Lamki Busaidy et autres

PURPOSE: Anaplastic thyroid cancer (ATC) is a highly lethal malignancy in which early detection of progression could allow timely treatment modifications and potentially improve outcomes. Novel circulating tumor DNA (ctDNA) assays allow the detection of molecular residual disease. We aimed to investigate …

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Neoadjuvant pembrolizumab in combination with dabrafenib and trametinib (DTP) for BRAF V600E-mutated anaplastic thyroid cancer ( BRAF m-ATC): A multicenter phase 2 trial.

Mark Zafereo, Jennifer Rui Wang, Naifa Lamki Busaidy, Ramona Dadu et autres

6008 Background: ATC patients present with advanced, often surgically unresectable disease with historically dismal prognosis. Median PFS and OS of DT without pembrolizumab were 6.7 and 13.5 months, respectively, in the ROAR trial. Neoadjuvant DTP achieved locoregional control without radical surgery in …

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Reimagining the Therapeutic Approach for Anaplastic Thyroid Cancer: The Roadmap to a Cure

Maria E. Cabanillas, Neal S. Akhave, Victoria Banuchi, Naifa Lamki Busaidy et autres

Anaplastic thyroid cancer (ATC) is an aggressive cancer that leads to rapid death if left untreated. However, recent advances in ATC treatment have dramatically changed the prognosis in a select group of patients with BRAFV600E mutations. In these patients, BRAF/MEK inhibitors have …

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Abstract LB414: Characterization of the genomic landscape of BRAF-, RAS-, and fusion-negative thyroid carcinomas underscores the role of tumor suppressor genes

Vicente Rodrigues Marczyk, Sarah Hamidi, Mark Zafereo, Steven G. Waguespack et autres

Abstract Background: Most non-medullary thyroid carcinomas (TC) are driven by mutually exclusive BRAF/RAS pathogenic variants or fusions involving RET, NTRK1/3, ALK, BRAF, or PPARG. However, none of these alterations are found in a subset of thyroid carcinomas (hereafter triple-negative TC). Methods: Patients …

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Letter to the Editor: New Current Procedural Terminology Codes for Radiofrequency Ablation of Thyroid Nodules Will Negatively Affect American Patients According to the Executive Council of the North American Society for Interventional Thyroidology

Jonathon O. Russell, Timothy C. Huber, Julia E. Noel, Maria Papaleontiou et autres

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Depth of invasion as an independent prognostic factor in early-stage oral cavity squamous cell carcinoma

Elizabeth S. Koh, Abhinav Pandey, Victoria Banuchi, William I. Kuhel et autres

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Transoral endoscopic vestibular approach Sistrunk procedure (TEVAS)—case report and scoping review

Marianne Yumi Nakai, Lucas Ribeiro Tenório, Jéssica da Silva Camarinha Oliveira, Laura Basso Ghirardello et autres

Background: Thyroglossal duct cyst (TGDC) is the most common congenital neck mass among the pediatric population. Less than 10% of the cases occur in adults. The standard of care for TGDC is surgical treatment with the Sistrunk procedure via a traditional transverse …

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