2721-LB: Obesity Switches Hepatic CB1 Signaling from Gi/oa-Mediated Lipolysis to Gsa-Driven Lipogenesis via the CREB-PPAR?-CD36-AMPK Axis
0 citationsDiabetes
George Kunos
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382Publications signalées
35420Citations signalées
1Affiliations récentes
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Domaines associés
Cannabis and Cannabinoid ResearchReceptor Mechanisms and SignalingAlcohol Consumption and Health EffectsDiet, Metabolism, and DiseaseNeurotransmitter Receptor Influence on Behavior
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Aquaporin 9 regulates acetaldehyde uptake, alcohol‐induced liver injury, and drinking behavior
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Monlunabant in adults with obesity and metabolic syndrome: Open‐label extension of a phase 2a trial
Filip K. Knop, George Kunos, Dror Dicker, Jean‐Sébastien Paquette et autres
1 citationDiabetes Obesity and Metabolism
A double-blind, randomized, placebo-controlled, phase 2 trial examined the efficacy and safety of monlunabant in adults with diabetic kidney disease
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2 citationsKidney International
Author response for "Monlunabant in adults with obesity and metabolic syndrome: open-label extension of a phase 2a trial"
Filip K. Knop, George Kunos, Dror Dicker, Jean‐Sébastien Paquette et autres
0 citations
Hepatic Aquaporin 8 Promotes Alcohol Consumption and Ameliorates Alcohol-Induced Liver Injury by Facilitating Acetaldehyde Excretion
Cheng Chen, Yuhong Lin, Dechun Feng, Yukun Guan et autres
0 citationsInternational Journal of Biological Sciences
Efficacy and safety of monlunabant in adults with obesity and metabolic syndrome: a double-blind, randomised, placebo-controlled, phase 2a trial
Filip K. Knop, George Kunos, Dror Dicker, Jean‐Sébastien Paquette et autres
14 citationsThe Lancet Diabetes & Endocrinology
CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice
Alexa Herrerias, Anna Oliverio, Szabolcs Dvorácskó, Lee Chedester et autres
3 citationsMolecular Psychiatry
Hepatic CB1 receptor signaling triggers Gi/oα-mediated lipolysis in lean mice but Gsα-mediated lipogenesis in obese mice
Jie Liu, Anna Oliverio, Grzegorz Godlewski, Radka Kočvarová et autres
6 citationsMetabolism
Exacerbated cardiac dysfunction from combined alcohol binge and synthetic cannabinoid use
János Pálóczi, Ozge Gunduz‐Cinar, Burhan Yokus, Bruno Paes‐Leme et autres
3 citationsBiomedicine & Pharmacotherapy
Opposite regulation of intestinal and intrahepatic CD8 + T cells controls alcohol-associated liver disease progression
Luca Maccioni, Yukun Guan, Mariia Kim, Maria A. Parra et autres
19 citationsGut
Cannabinoid receptors in GtoPdb v.2025.1
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1 citationIUPHAR/BPS Guide to Pharmacology CITE
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