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Profil bibliographique

Camelia Iancu‐Rubin

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

66Publications signalées
1194Citations signalées
0Affiliations récentes

Les domaines associés

Myeloproliferative Neoplasms: Diagnosis and TreatmentChronic Myeloid Leukemia TreatmentsPlatelet Disorders and TreatmentsAcute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Les publications récentes

Accès ouvert 2023 other OpenAlex

Data from Immune Checkpoint Blockade Enhances Shared Neoantigen-Induced T-cell Immunity Directed against Mutated Calreticulin in Myeloproliferative Neoplasms

Cansu Cimen Bozkus, Vladimir Roudko, John P. Finnigan, John O Mascarenhas et autres

Abstract Somatic frameshift mutations in the calreticulin (CALR) gene are key drivers of cellular transformation in myeloproliferative neoplasms (MPN). All patients carrying these mutations (CALR+ MPN) share an identical sequence in the C-terminus of the mutated CALR protein (mut-CALR), with the potential …

0 citations
Accès ouvert 2023 other OpenAlex

Data from Immune Checkpoint Blockade Enhances Shared Neoantigen-Induced T-cell Immunity Directed against Mutated Calreticulin in Myeloproliferative Neoplasms

Cansu Cimen Bozkus, Vladimir Roudko, John P. Finnigan, John O Mascarenhas et autres

Abstract Somatic frameshift mutations in the calreticulin (CALR) gene are key drivers of cellular transformation in myeloproliferative neoplasms (MPN). All patients carrying these mutations (CALR+ MPN) share an identical sequence in the C-terminus of the mutated CALR protein (mut-CALR), with the potential …

0 citations
Accès ouvert 2022 article OpenAlex

Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes

Kamaleldin E. Elagib, Ashton T. Brock, Cara Clementelli, Goar Mosoyan et autres

Infantile (fetal and neonatal) megakaryocytes (Mks) have a distinct phenotype consisting of hyperproliferation, limited morphogenesis, and low platelet production capacity. These properties contribute to clinical problems that include thrombocytopenia in neonates, delayed platelet engraftment in recipients of cord blood stem cell transplants, …

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14 citations Journal of Clinical Investigation

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