Accès ouvert
2026
other
OpenAlex
Mario Falchi, Lilian Varricchio, Francesca Masiello, Agostino Tafuri et autres
Calreticulin (CALR) is a multifunctional protein normally found within the lumen of the endoplasmic reticulum that mediates the cellular response to Ca2+ by chaperoning other proteins to their acting sites. Somatic loss-of-function mutations in the CALR gene were recently discovered in 70% …
Accès ouvert
2024
paratext
OpenAlex
Rim Abdallah, Suchitra S. Acharya, Joel Addams, Ahmad H. Al-Huniti et autres
us, sa, in, nl, ca
(code pays fourni par la source)
2024
book-chapter
OpenAlex
Camelia Iancu‐Rubin, Rona Singer Weinberg
us
(code pays fourni par la source)
2024
book-chapter
OpenAlex
Camelia Iancu‐Rubin, Rona Singer Weinberg
2024
article
OpenAlex
Harshad V. Joshi, Elaine Bich Than, Y. Chowdhury, Aharon Oren et autres
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Alla Keyzner, Jacques Mario Azzi, Rita M. Jakubowski, Sharon Tindle et autres
us
(code pays fourni par la source)
Accès ouvert
2023
other
OpenAlex
Cansu Cimen Bozkus, Vladimir Roudko, John P. Finnigan, John O Mascarenhas et autres
Abstract Somatic frameshift mutations in the calreticulin (CALR) gene are key drivers of cellular transformation in myeloproliferative neoplasms (MPN). All patients carrying these mutations (CALR+ MPN) share an identical sequence in the C-terminus of the mutated CALR protein (mut-CALR), with the potential …
Accès ouvert
2023
supplementary-materials
OpenAlex
Cansu Cimen Bozkus, Vladimir Roudko, John P. Finnigan, John O Mascarenhas et autres
This file contains supplementary methods, reference, tables (3), figures (10) and the corresponding legends for tables and figures.
Accès ouvert
2023
supplementary-materials
OpenAlex
Cansu Cimen Bozkus, Vladimir Roudko, John P. Finnigan, John O Mascarenhas et autres
This file contains supplementary methods, reference, tables (3), figures (10) and the corresponding legends for tables and figures.
Accès ouvert
2023
other
OpenAlex
Cansu Cimen Bozkus, Vladimir Roudko, John P. Finnigan, John O Mascarenhas et autres
Abstract Somatic frameshift mutations in the calreticulin (CALR) gene are key drivers of cellular transformation in myeloproliferative neoplasms (MPN). All patients carrying these mutations (CALR+ MPN) share an identical sequence in the C-terminus of the mutated CALR protein (mut-CALR), with the potential …
Accès ouvert
2022
article
OpenAlex
Kamaleldin E. Elagib, Ashton T. Brock, Cara Clementelli, Goar Mosoyan et autres
Infantile (fetal and neonatal) megakaryocytes (Mks) have a distinct phenotype consisting of hyperproliferation, limited morphogenesis, and low platelet production capacity. These properties contribute to clinical problems that include thrombocytopenia in neonates, delayed platelet engraftment in recipients of cord blood stem cell transplants, …
us, fr, jp, cn
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Stacey-Ann Whittaker Brown, Camelia Iancu‐Rubin, Adam Aboelela, Alex Abrahams et autres
us
(code pays fourni par la source)