Ting-Ting Wen

Intraoperative Collapse During First-Trimester Abortion: Hyperleukocytosis Crisis, Thrombotic Pulmonary Embolism, or Amniotic Fluid Embolism?

Ting-Ting Wen, Yu Zhang, Yushan Zhong, Shengwen Song

Background: Hyperleukocytosis in patients with hematologic malignancies poses significant perioperative risks, including leukostasis, coagulopathy, tumor lysis syndrome and hyperinflammatory syndrome. Additionally, pregnancy and hyperleukocytosis predispose patients to a hypercoagulable state, increasing the risk of thrombosis. On the other hand, amniotic fluid embolism …

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Chitin Synthases in Fungi: A Comprehensive Review of Classification, Catalytic Mechanism, and Functional Roles

Lin Xu, Ting-Ting Wen, Cai-Yu Chen, L. Sun et autres

Fungi contain the most complex chitin synthase family, which contributes to chitin biosynthesis and cell wall rigidity. In the past decades, their functions involved in morphological diversity, viability, and virulence of fungi have been well investigated using typical molecular methods such as …

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Functional Characterization of a β-1,3-Glucanosyltransferase CmGel4 in Cordyceps militaris Using a Precise CRISPR-Cas9 Genome-Editing System

Ting-Ting Wen, Xu Lin, Rui Jin, Zhiyu Liu et autres

Cordyceps militaris polysaccharides, especially β-glucans, have presented significant antitumor, hypoglycemic, and immunomodulatory activities. However, the enzymes involved in the branching formation of C. militaris β-glucans remain to be elucidated. In the present study, a 1.69-kb β-1,3-glucanosyltransferase CmGel4 gene putatively involved in β-glucan …

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Risk factors for esophageal pain after peroral endoscopic myotomy under general anesthesia: A retrospective study

Jia‐Xin Yin, Wenqi Zhang, Xu Han, Ting-Ting Wen et autres

BACKGROUND: Peroral endoscopic esophageal myotomy (POEM) is an innovative, minimally invasive endoscopic technique that has been widely adopted and recognized for the clinical management of achalasia because of its advantages of minimal trauma and rapid recovery. Nevertheless, clinical data have indicated that …

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Caspofungin-lavender conjugates halt Alternaria rot in peaches: Unravelling antifungal mechanisms in-vitro, in-vivo, and in-silico

Syed Asim Shah Bacha, Shashi Kiran, Ting-Ting Wen, Asif Ali Khan et autres

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CRISPR-Cas9/Safe Harbor-Targeted Overexpression of Glucan Synthase Gene CmGls in Edible Mushroom Cordyceps militaris

Ting-Ting Wen, Yumeng Yang, Yi-Xin Zhang, Meng-Qian Liu et autres

The membrane-integrated β-1,3-glucan synthase is the key enzyme involved in the biosynthesis of the core component β-1,3-glucan of the fungal cell wall. To date, the precise and targeted insertion of the β-1,3-glucan synthase gene into the genomes of edible fungi for safe …

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Short-term outcomes and risk factors for mortality in neonatal cardiac surgeries with cardiopulmonary bypass: a 5-year single-center report

Xianghong Zhang, Ting-Ting Wen, Jiajie Fan, Yunxiang Qiu et autres

Background Open-heart surgeries carry significantly greater risks in neonates than in older children. The current study aimed to analyze the short-term outcomes and risk factors for mortality in neonates undergoing cardiac surgeries. Methods This retrospective analysis included neonates who underwent cardiac surgeries …

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Fungal β-1, 3-glucanosyltransferases: A comprehensive review on classification, catalytic mechanism and functional role

Ting-Ting Wen, Lei Sun, Fengjie Cui, Xin‐Yi Zan et autres

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Remote Sensing-Based LULP Change and Its Effect on Ecological Quality in the Context of the Hainan Free Trade Port Plan

Pei Liu, Ting-Ting Wen, Ruimei Han, Lin Zhang et autres

The study of Land Use and Landscape Patterns (LULPs) changes and their ecological quality effects in Haikou city under the background of the Hainan Free Trade Port Plan (HFTPP) helps to promote coordinated development between cities and the environment. To date, most …

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Persistent postoperative hypotension caused by subclinical empty sella syndrome after a simple surgery: A case report

Kang-Mei Zhao, Jiasheng Hu, Shengmei Zhu, Ting-Ting Wen et autres

BACKGROUND: Empty sella is an anatomical and radiological finding of the herniation of the subarachnoid space into the pituitary fossa leading to a flattened pituitary gland. Patients with empty sella may present with various symptoms, including headache due to intracranial hypertension and …

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A serotonin transporter polymorphism is associated with postoperative nausea and vomiting

Ulrike M. Stamer, Maxime Schmutz, Ting-Ting Wen, Vanessa Banz et autres

BACKGROUND: Clinical risk factors for postoperative nausea and vomiting (PONV) are well described, whereas genetic findings are conflicting. OBJECTIVE: The aim of this study was to investigate a possible association of genetic variants and nongenetic variables with the incidence and severity of …

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Regulation of keratinocyte behavior by laminin 332 and alpha/beta 1 integrins

Ting-Ting Wen