Pauline Manchon

WED-067 ActiMASH: a novel blood-based score to measure liver activity in patients with MASLD

Louise Biquard, Laure Elkrief, Marion Tanguy, Alix Cointet et autres

Real-world outcomes of immune checkpoint inhibitors in people with HIV and skin cancer: a multicentre study

Andréa Clément de Givry, Pauline Manchon, Marianne Veyri, Julie Delyon et autres

BACKGROUND: People living with HIV (PWH) have an increased risk of developing aggressive skin cancers, yet they have been largely excluded from immune checkpoint inhibitor (ICI) trials. Consequently, evidence on the safety and efficacy of ICIs in this population remains scarce, particularly …

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Improving Care Delivery to Increase Smoking Cessation after a Stroke: A 2023 Nationwide Cross-Sectional Study of Stroke Units in France

Skerdi Haviari, Pauline Manchon, Caroline Quintin, Pierre Amarenco et autres

INTRODUCTION: Although guidelines recommend smoking cessation after stroke, smoking cessation may not be adequately prioritized in stroke units. This study evaluated the practices of French stroke neurologists with respect to smoking cessation and sought to identify barriers to their involvement. METHODS: All …

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Utilisation des inhibiteurs de points de contrôle immunitaire chez les patients vivant avec le VIH traités pour un cancer cutané : premières données de l’étude rétrospective multicentrique SkinICIHIV

Andréa Clément de Givry, Pauline Manchon, Marianne Veyri, Nausicaa Malissen et autres

Morphometric Quantification of Steatosis and Fibrosis in Metabolic Liver Disease Associated With Type 2 Diabetes

O Fourati, Pauline Manchon, Philippe Garteiser, Laurent Castéra et autres

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Etat de santé initiale des patients (pts) primo-arrivant (PA) consultants en médecine générale (MG) en Seine Saint Denis (SSD) : cohorte ANRS CoPAMViL

A. Sautereau, K. Erny, H. Azzeddine, Pauline Manchon et autres

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Geriatric-led transitional care for older adults discharged from the emergency department: impact on hospital readmissions and disability. Protocol for the controlled prospective quasi-experimental study LASUITE

Manuel Sanchez, Philippine Eloy, Virginie Godard, Marina Coutauchaud et autres

BACKGROUND: Even when older people are discharged directly home after an emergency department (ED) visit, the risk of deterioration of health status and loss of independence persists. We hypothesize that among older adults discharged from the ED, hospital-community transition care provided by …

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ACBP/DBI neutralization for the experimental treatment of fatty liver disease

Omar Motiño, Flavia Lambertucci, Adrien Joseph, Sylvère Durand et autres

Abstract Acyl-CoA binding protein (ACBP), also known as diazepam-binding inhibitor (DBI), is an extracellular checkpoint of autophagy. Here, we report that patients with histologically confirmed metabolic-associated steatohepatitis (MASH) or liver fibrosis exhibit elevated levels of circulating ACBP/DBI protein as compared to non-affected …

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WED-245 Should specific cutoffs be used for diagnosing fibrotic MASH in patients with type 2 diabetes using FAST, MAST, MEFIB and FNI?

Laurent Castéra, Philippe Garteiser, Cédric Laouenan, Tiphaine Vidal-Trécan et autres

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

Astrid Marchal, Elizabeth T. Cirulli, Iva Neveux, Evangelos Bellos et autres

Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B∗15:01 allele and asymptomatic SARS-CoV-2 infection in unvaccinated individuals was recently reported, suggesting a contribution of …

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Prospective head-to-head comparison of non-invasive scores for diagnosis of fibrotic MASH in patients with type 2 diabetes

Laurent Castéra, Philippe Garteiser, Cédric Laouenan, Tiphaine Vidal-Trécan et autres

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Maternal and neonatal outcomes of French prospective multicenter cohort study COVIPREG during the first two COVID-19 waves

Alexandre Vivanti, Camille Couffignal, Jeanne Sibiude, Anne‐Gaël Cordier et autres

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