Will Gillett

Genome Sequence of Francisella tularensis subspecies holarctica Strain FSC200, Isolated from a Child with Tularemia

Kerstin Svensson, Andreas Sjödin, Mona Byström, Malin Granberg et autres

Here we report the complete, accurate 1.89-Mb genome sequence of Francisella tularensis subsp. holarctica strain FSC200, isolated in 1998 in the Swedish municipality Ljusdal, which is in an area where tularemia is highly endemic. This genome is important because strain FSC200 has …

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Evolution of Burkholderia pseudomallei in Recurrent Melioidosis

Hillary S. Hayden, M. Brittnacher, Elizabeth H. Sims, Elizabeth Ramage et autres

Burkholderia pseudomallei, the etiologic agent of human melioidosis, is capable of causing severe acute infection with overwhelming septicemia leading to death. A high rate of recurrent disease occurs in adult patients, most often due to recrudescence of the initial infecting strain. Pathogen …

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ANALYSES OF THE COMPLETE CHLOROPLAST GENOME SEQUENCES OF TWO MEMBERS OF THE PELAGOPHYCEAE: AUREOCOCCUS ANOPHAGEFFERENS CCMP1984 AND AUREOUMBRA LAGUNENSIS CCMP15071

Han Chuan Ong, Steven W. Wilhelm, Christopher J. Gobler, George S. Bullerjahn et autres

Heterokont members of the Pelagophyceae form the massive brown tides that have continually plagued the coastal regions of the eastern U.S. seaboard and the Gulf of Mexico. To gain a better understanding of the photosynthetic competence that may be linked to their …

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Analysis of the Genome of the Escherichia coli O157:H7 2006 Spinach-Associated Outbreak Isolate Indicates Candidate Genes That May Enhance Virulence

Bridget R. Kulasekara, Michael A. Jacobs, Yang Zhou, Zaining Wu et autres

In addition to causing diarrhea, Escherichia coli O157:H7 infection can lead to hemolytic-uremic syndrome (HUS), a severe disease characterized by hemolysis and renal failure. Differences in HUS frequency among E. coli O157:H7 outbreaks have been noted, but our understanding of bacterial factors …

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Methylobacterium Genome Sequences: A Reference Blueprint to Investigate Microbial Metabolism of C1 Compounds from Natural and Industrial Sources

Stéphane Vuilleumier, Ludmila Chistoserdova, Ming‐Chun Lee, Françoise Bringel et autres

BACKGROUND: Methylotrophy describes the ability of organisms to grow on reduced organic compounds without carbon-carbon bonds. The genomes of two pink-pigmented facultative methylotrophic bacteria of the Alpha-proteobacterial genus Methylobacterium, the reference species Methylobacterium extorquens strain AM1 and the dichloromethane-degrading strain DM4, were …

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Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients

Hillary S. Hayden, Will Gillett, Channakhone Saenphimmachak, Yang Zhou et autres

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Mapping and sequencing of structural variation from eight human genomes

Jeffrey M. Kidd, Gregory M. Cooper, William F. Donahue, Hillary S. Hayden et autres

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Closing gaps in the human genome with fosmid resources generated from multiple individuals

Donald Bovee, Yang Zhou, Eric Haugen, Zaining Wu et autres

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Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains

Laurence Rohmer, Christine T. Fong, Simone Abmayr, Michael Wasnick et autres

BACKGROUND: Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause disease. To uncover the factors that allow subspecies tularensis and holarctica to be pathogenic to humans, we compared their genome sequences …

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The DNA sequence and biological annotation of human chromosome 1 (vol 441, pg 315, 2006)

Simon G. Gregory, KF Barlow, K. E. McLay, Rajinder Kaul et autres

Erratum: The DNA sequence and biological annotation of human chromosome 1

Simon G. Gregory, K. F. Barlow, K. E. McLay, Rajinder Kaul et autres

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The DNA sequence and biological annotation of human chromosome 1

Simon G. Gregory, K. F. Barlow, K. E. McLay, Rajinder Kaul et autres

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