Maria de Lourdes Meirelles Noviello

Spontaneous T. gondii neuronal encystment induces structural neuritic network impairment associated with changes of tyrosine hydroxilase expression

Joana Lobato Barbosa, Samantha Ribeiro Béla, Mayra Fernanda Ricci, Maria de Lourdes Meirelles Noviello et autres

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Influence of indigenous microbiota on experimental toxoplasmosis in conventional and germ‐free mice

B.B. Nascimento, Christiane Teixeira Cartelle, Maria de Lourdes Meirelles Noviello, Breno Veloso Pinheiro et autres

Toxoplasmosis represents one of the most common zoonoses worldwide. Its agent, Toxoplasma gondii, causes a severe innate pro-inflammatory response. The indigenous intestinal microbiota promotes host animal homoeostasis and may protect the host against pathogens. Germ-free (GF) animals provide an important tool for …

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Correction: Enteric Neuronal Damage, Intramuscular Denervation and Smooth Muscle Phenotype Changes as Mechanisms of Chagasic Megacolon: Evidence from a Long-Term Murine Model of Tripanosoma cruzi Infection

Camila França Campos, Sílvia Dantas Cangussú, Ana Luiza Cassin Duz, Christiane Teixeira Cartelle et autres

[This corrects the article DOI: 10.1371/journal.pone.0153038.].

Enteric Neuronal Damage, Intramuscular Denervation and Smooth Muscle Phenotype Changes as Mechanisms of Chagasic Megacolon: Evidence from a Long-Term Murine Model of Tripanosoma cruzi Infection

Camila França Campos, Sílvia Dantas Cangussú, Ana Luiza Cassin Duz, Christiane Teixeira Cartelle et autres

We developed a novel murine model of long-term infection with Trypanosoma cruzi with the aim to elucidate the pathogenesis of megacolon and the associated adaptive and neuromuscular intestinal disorders. Our intent was to produce a chronic stage of the disease since the …

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Leprosy classification methods: a comparative study in a referral center in Brazil

Ismael Alves Rodrigues Júnior, Letícia Trivellato Gresta, Maria de Lourdes Meirelles Noviello, Christiane Teixeira Cartelle et autres

OBJECTIVES: Different methods for the classification of leprosy have been proposed since the 1930s. The aim of this study was to compare the current methods at a referral center in Brazil. METHODS: The World Health Organization (WHO) operational classification was compared to …

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Pathological changes in acute experimental toxoplasmosis with Toxoplasma gondii strains obtained from human cases of congenital disease

Breno Veloso Pinheiro, Maria de Lourdes Meirelles Noviello, Mariana Mesquita-Cunha, Alice Thomáz Tavares et autres

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Prolonged ingestion of ovalbumin diet by Ova sensitized mice suppresses mBSA-induced arthritis

Maria de Lourdes Meirelles Noviello, Nathália Vieira Batista, Luana Pereira Antunes Dourado, Rafaela Vaz Sousa Pereira et autres

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Prolonged Antigen Ingestion by Sensitized Mice Ameliorates Airway Inflammation

Maria de Lourdes Meirelles Noviello, Nathália Vieira Batista, Luana Pereira Antunes Dourado, Denise Carmona Cara

Food allergy frequently precedes or coexists with respiratory allergy, and although restriction of contacts with the allergen is the elected clinical procedure, oral immunotherapy (OIT) has proven to be surprisingly efficient in clinical trials. We investigated whether prolonged restriction and voluntary exposure …

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Experimental food allergy leads to adipose tissue inflammation, systemic metabolic alterations and weight loss in mice

Luana Pereira Antunes Dourado, Maria de Lourdes Meirelles Noviello, Débora Moreira Alvarenga, Zélia Menezes et autres

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Role of IL-4 in aversion induced by food allergy in mice

Luana Pereira Antunes Dourado, Janaína Cláudia da Silva Saldanha, Daniela Gargiulo, Maria de Lourdes Meirelles Noviello et autres

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Brazilian Green Propolis Inhibits Inflammatory Angiogenesis in a Murine Sponge Model

Sandra Aparecida Lima de Moura, Mônica Alves Neves Diniz Ferreira, Sílvia Passos Andrade, Maria Letícia Costa Reis et autres

Angiogenesis and inflammation are persistent features of several pathological conditions. Propolis, a sticky material that honeybees collect from living plants, has been reported to have multiple biological effects including anti-inflammatory and anti-neoplasic activities. Here, we investigated the effects of water extract of …

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