Meredith Palmore

Prenatal exposure to fluoride in public water and child cognition in the US ECHO cohort, 2006-2019

Katrina R. Simon, Tessa Bloomquist, Tushara Rajeev, Alexis Hernandez et autres

Prior studies suggest fluoride exposure in drinking water above 1500 μg/L is associated with lower child cognition, but evidence is limited at lower exposure levels and in U.S. populations. We evaluated whether prenatal exposure to fluoride in regulated public drinking water was …

us, Afrique du Sud (code pays fourni par la source)

Does gestational vitamin D attenuate the negative effects of prenatal depression on offspring emotional and behavioral problems? Findings in the ECHO cohort

Alison E. Hipwell, Irene T. Tung, Meredith Palmore, Melissa Moser Melough et autres

BACKGROUND: Prenatal depression is associated with offspring behavioral problems, but heterogeneity in the strength of this association is not well understood. Maternal vitamin D concentration during pregnancy is important for fetal brain development and may help explain this variability, with potential differences …

us, mx (code pays fourni par la source)

Gestational vitamin D concentration and child cognitive development: a longitudinal cohort study in the Environmental influences on Child Health Outcomes Program

Melissa Moser Melough, Monica McGrath, Meredith Palmore, Brent R. Collett et autres

us (code pays fourni par la source)

Prenatal ambient air pollution associations with DNA methylation in asthma- and allergy-relevant genes: findings from ECHO

Meredith Palmore, Emma E. Thompson, Fang Fang, Theresa M. Bastain et autres

Abstract Prenatal exposure to air pollution is an important risk factor for child health outcomes, including asthma. Identification of DNA methylation changes associated with air pollutant exposure can provide new intervention targets to improve children’s health. The aim of this study is …

us (code pays fourni par la source)

Comparison of Race-Neutral versus Race-Specific Spirometry Equations for Evaluation of Child Asthma

Amy L. Non, Xiuhong Li, Miranda R. Jones, Emily Oken et autres

Abstract Rationale Race-based estimates of pulmonary function in children could influence the evaluation of asthma in children from racial and ethnic minoritized backgrounds. Objectives To determine if race-neutral (Global Lung Function Initiative [GLI]-Global) versus race-specific (GLI–Race-Specific) reference equations differentially impact spirometry evaluation …

us (code pays fourni par la source)

DNA methylation signatures of prenatal socioeconomic position associated with 36-month language outcomes

Meghna Rajaprakash, Meredith Palmore, Kelly M. Bakulski, Ellen M. Howerton et autres

Socioeconomic position (SEP), which reflects one’s position in society and access to resources, is strongly tied to neurodevelopment and is associated with epigenetic changes. AIM: This study examined whether DNA methylation signatures of prenatal SEP, measured in birth samples, are associated with …

us, Cameroun (code pays fourni par la source)

Analysis of Pregnancy Complications and Epigenetic Gestational Age of Newborns

Dana Dabelea, Nicole R. Bush, Margaret Rita Karagas, Andrés Cárdenas et autres

Importance: Preeclampsia, gestational hypertension, and gestational diabetes, the most common pregnancy complications, are associated with substantial morbidity and mortality in mothers and children. Little is known about the biological processes that link the occurrence of these pregnancy complications with adverse child outcomes; …

us (code pays fourni par la source)

FHL5 Controls Vascular Disease–Associated Gene Programs in Smooth Muscle Cells

Doris Wong, Gaelle E Auguste, Christian L. Lino Cardenas, Adam W. Turner et autres

Background: Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial infarction, and hypertension. However, the lack of mechanistic insights for many GWAS loci limits their translation into the clinic. Among these loci …

us, de, fi, nl, se, au (code pays fourni par la source)

Greater Gestational Vitamin D Status is Associated with Reduced Childhood Behavioral Problems in the Environmental Influences on Child Health Outcomes Program

Melissa Moser Melough, Mingyi Li, Ghassan Badri Hamra, Meredith Palmore et autres

us (code pays fourni par la source)

Analysis of Pregnancy Complications and Epigenetic Gestational Age of Newborns

Christine Ladd‐Acosta, Elizabeth Vang, Emily S. Barrett, Catherine M. Bulka et autres

Importance: Preeclampsia, gestational hypertension, and gestational diabetes, the most common pregnancy complications, are associated with substantial morbidity and mortality in mothers and children. Little is known about the biological processes that link the occurrence of these pregnancy complications with adverse child outcomes; …

us (code pays fourni par la source)

Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019 Through August 2021

Monique M. Hedderson, Traci A. Bekelman, Mingyi Li, Emily A. Knapp et autres

Importance: The COVID-19 pandemic led to widespread lockdowns and school closures that may have affected screen time among children. Although restrictions were strongest early in the pandemic, it is unclear how screen time changed as the pandemic progressed. Objective: To evaluate change …

us (code pays fourni par la source)

DNA methylation signatures as biomarkers of socioeconomic position

Meghna Rajaprakash, Lorraine Tiera Dean, Meredith Palmore, Sara B. Johnson et autres

This review article provides a framework for the use of deoxyribonucleic acid (DNA) methylation (DNAm) biomarkers to study the biological embedding of socioeconomic position (SEP) and summarizes the latest developments in the area. It presents the emerging literature showing associations between individual- …

us (code pays fourni par la source)