Wei Lei

Machine learning model based on spontaneous brain activity and functional connectivity for identifying patients with internet gaming disorder

Mingling Yu, Zhengyuan Xiao, Shengdan Liu, Danping Zhang et autres

cn (code pays fourni par la source)

Quantitative transcriptomic and metabolic analyses reveal the roles of RpoS and Crp in the acid resistance system 1 in Escherichia coli

Wei Zhang, L L Zhang, J Q Xu, Q Y Huang et autres

ABSTRACT Foodborne pathogens exploit acid resistance (AR) mechanisms to survive harsh environments, such as the stomach, increasing contamination risk. While the sigma factor RpoS and cyclic AMP receptor protein (Crp) are known mediators of AR, their systemic regulatory networks remain unclear. Here, …

cn, us (code pays fourni par la source)

GFP-DWHML: An EEG microstate analysis method using GFP-based dynamic weighting for hybrid metric learning

Yi-Xiang Wang, C S Yang, Wei Lei, Yang Xiao

cn (code pays fourni par la source)

Astragaloside IV and ceramide IIIB co-modified ferulic acid ethosomes: a promising novel approach for skin anti-aging

Zhixin Wen, Hang Lu, Haoquan Yu, Yiyuan Liu et autres

Ferulic acid (FA) has multiple anti-aging functions but is limited by poor solubility, low bioavailability, and unclear mechanism in skincare. To overcome these challenges, we have developed ferulic acid ethosomes (FA-ES) co-modified with astragaloside IV and ceramide IIIB. Stability of FA-ES was …

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AAV9 ‐Mediated Intrastriatal Delivery of Mutant HTT With 82 CAG Repeats Induces Huntington's Disease‐Like Pathology and Behavioral Deficits in Mice

Lin Huang, Yazhou Tang, Yuan Wang, Yali Tan et autres

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by CAG repeat expansion in the HTT gene. Existing toxin-induced and genetic models provide important insights, but none fully replicate the progressive pathology of HD. An AAV9-mediated striatal mouse model expressing mutant …

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Aberrant degree centrality and functional connectivity in patients with internet gaming disorder

Mingling Yu, Qian Li, Yu Mao, Yue He et autres

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Hierarchical optimization control strategy of hybrid electric vehicle platoon under communication failure

Jingyao Wang, Zhen Zeng, Wei Lei, Haoxu Ye et autres

This research proposes a DRL-based hierarchical optimization control strategy for connected HEV platoons through a cloud platform, addressing strong nonlinearity and communication failure issues. The strategy uses a signal-interference-plus-noise ratio model to detect network failures by considering distance, signal path loss, and …

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Compounds with dual glutaminase inhibition and Nrf2 activation activities enhance morphine analgesia and reduce pain sensitization in chemotherapy-induced peripheral neuropathy mouse model

Valentin Kliebe, Hilal F Elnaham, Michael K. Thompson, Sid L. Sagna et autres

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Aha1 Inhibition Enhances Morphine Analgesia in Post-operative Pain Model

Ishrat Jahan, Brian S. J. Blagg, Wei Lei

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Chemotherapy-Induced Peripheral Neuropathy: A Recent Update on Pathophysiology and Treatment

Marina Mattar, Florence Umutoni, M. Wambui Wamburu, R. C. Turner et autres

Chemotherapy-induced peripheral neuropathy (CIPN) is a major long-lasting side effect of some chemotherapy drugs, which threatens cancer survival rate. CIPN mostly affects sensory neurons and occasionally motor neurons, causing numbness, tingling, discomfort, and burning pain in the upper and lower extremities. The …

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Research hotspots and trends in healthcare workers' resilience: A bibliometric and visualized analysis

Luhuan Yang, Zifeng Li, Yunhong Lei, Jinglan Liu et autres

Background: The resilience of healthcare workers has gained increasing attention, yet comprehensive studies focusing on recent trends and developments are scarce. We conducted an extensive bibliometric analysis from inception to 2023 to address this gap. Methods: Publications on healthcare workers' resilience were …

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Dynamic Alternative Polyadenylation during Litopenaeus Vannamei Metamorphosis Development

Xueqin Yang, Xiuli Chen, Chengzhang Liu, Zezhong Wang et autres

As an important mechanism in the post-transcriptional regulation of eukaryotic gene expression, alternative polyadenylation (APA) plays a key role in biological processes such as cell proliferation and differentiation. However, the role and dynamic pattern of APA during Litopenaeus vannamei metamorphosis are poorly …

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