Bing Jiang

High-Responsivity ReMoS 2 Photodetector on Gallium Nitride Patterned Substrate for Visible-Light Image Sensing and Communication Applications

Bing Jiang, Jun He, Jiachang Guo, Xue Fan et autres

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Editorial: In vivo applications of nanozymes

Bing Jiang

longer whether nanomaterials can mimic enzymes under simplified conditions, but whether they can function reliably within heterogeneous pathological microenvironments. The six contributions collected in this Research Topic show that progress clearly. Across four original investigations and two reviews, the collection reveals a …

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Abstract 1479: CAB: A confidence-aware sequence model enabling high-throughput prediction of mutation-driven binding affinity change in antibody-based cancer therapeutics.

Yuanfei Sun, Bing Jiang, Huiping Liu

Abstract Background: Computational prediction of antibody-antigen (Ab-Ag) affinity is increasinglyimportant for designing tumor-targeting therapeutics, enabling rapid in-silico affinity maturation,and optimization of formats such as bispecifics and ADC. However, existing models are trainedalmost exclusively on positive binding cases with measurable affinity, creating a …

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Antimicrobial Nanozymes: Structure–Activity-Guided Design, Synergy, and Applications

Ying Liu, Kaili Guo, Jingnan Shi, Xiang Guo et autres

Nanozymes are emerging as versatile antimicrobial agents to tackle drug-resistant infections and biofilm-associated persistence. In this review, we present an integrated framework that links natural enzyme-mediated host defense to the rational development of antimicrobial nanozymes, and summarize recent advances through a mechanism-materials-engineering-application …

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Liyuan Law: GaN fast-charging technology development trend

Kangkai Fan, Yutong Wu, Bing Jiang, Kaifeng Wang et autres

Abstract The article puts forward the “Liyuan Law,” which means that the output power of commercial GaN fast chargers grows by an average of about 50% every 12 months. Research from 2018 to 2025 on consumer-grade and industrial-grade GaN products found that …

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Probiotic-based oral vaccine mucosal delivery system enabling genetically encoded dual-antigen arrays

Yale Yue, Xin Qi, Yuanyuan Zhu, Dandan Zhu et autres

Oral vaccines provide a non-invasive approach for cancer immunotherapy but face challenges in gastrointestinal stability, antigen presentation, and mucosal delivery. Here, we present an engineered probiotic-based oral vaccine system, BacOR-Fn-T+phiX174, featuring genetically encoded dual-antigen ferritin arrays and inducible bacterial lysis. Upon oral …

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Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang et autres

Abstract Mild‐temperature photothermal therapy (mPTT) is attractive for cancer treatment due to its safety and precision but is limited by heat shock protein 70 (HSP70)‐mediated thermotolerance, which allows tumor cells to survive sublethal heating. Herein, a thermo‐responsive cascade nanozyme system is reported …

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Proton‐Driven Deformability Enables Nanozyme‐Integrated Vaccine for Enhanced Tumor Immunotherapy

Jingyi An, Yijie Yang, Yiming Feng, Shuyu Wang et autres

Abstract Cancer immunotherapy leveraging vaccine‐based approaches has emerged as a promising strategy for long‐term tumor regression and metastasis prevention. However, the design of effective vaccines remains challenging due to the need for efficient lymph node (LN) targeting, dendritic cell (DC) uptake, and …

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Precision Reconstruction of Postoncologic Maxillary Defect Using a 3D-Printed PEEK Implant: A Focus on Esthetic and Functional Outcomes

Wenhao Cheng, Bing Jiang, Na Bai, Jian Sun et autres

Radiotherapy and chemotherapy can lead to local skin adhesion, fibrosis, poor vascular activity, and weakened tissue recovery capacity. Accurately reconstructing the maxilla after radiotherapy and chemotherapy has become a focal issue for oral and maxillofacial surgeons. This article presents a case of …

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Nanozyme eye drops for retinal barrier penetration and vasculopathy repair

Xue Bai, Shuyu Wang, Tingting Wu, Lulu Wang et autres

Retinal neovascularization diseases cause vision impairment due to abnormal blood vessel growth in the retina. Current treatments, including repeated intraocular anti-vascular endothelial growth factor injections, are invasive and often lead to discomfort and complicated hemorrhages. Here, we developed a noninvasive nanozyme eye …

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Ferritin-Conjugated PROTAC Strategy for ERCC1/XPF Degradation and Platinum Sensitization in Resistant Tumors

Shenghui Wang, Runze Zhao, Shuyu Wang, Zhenwei Gui et autres

Cisplatin resistance remains a major clinical challenge in cancer therapy, often driven by the upregulation of DNA repair pathways. Here, we present a dual-functional nanotherapeutic system (HFn-NERiP-Pt(IV)) combining a glutathione-responsive PROTAC (NERiP) with a ferritin nanocarrier for targeted ERCC1/XPF degradation and enhanced …

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Topology and Control Strategy of an ISOP-LLC Cascaded with Buck Converter for Seafloor Observation Network

Bing Jiang, Jiaxing Lei, Shuang Feng, Lei Huang et autres

The power supply of seafloor observation network connection box needs to meet the core requirements of medium-voltage direct current (MVDC) wide-range input, high power density and resistant to load disturbance. Aiming at the issues of realizing wide-range input and complex input voltage …

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