Bo Zeng

Dynamic Echocardiographic Trajectory Phenotypes During Veno‐Arterial Extracorporeal Membrane Oxygenation and Their Association With In‐Hospital Mortality: A Multicenter Cohort Study

Zhe Li, Wan Chen, Chenglong Li, Guozheng Qiu et autres

BACKGROUND: Current risk stratification for veno-arterial extracorporeal membrane oxygenation relies on static assessments, ignoring dynamic cardiac evolution. We aimed to identify longitudinal echocardiographic trajectory phenotypes and evaluate their association with in-hospital mortality. METHODS: We analyzed 2034 adults receiving veno-arterial extracorporeal membrane oxygenation …

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Carnosine ameliorates renal ischaemia–reperfusion injury by modulating MFN2/OPA1 to restore mitochondrial homeostasis in UPB1 deficiency

Yao Zhou, Jinshi Liu, Lingzhang Meng, Xiaojing Liang et autres

Renal ischaemia–reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) and a critical determinant of transplant outcomes. β-ureidopropionase (UPB1) is the terminal enzyme of the pyrimidine degradation pathway, catalysing the production of β-alanine — the rate-limiting precursor for carnosine …

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Early metabolic trajectory and sedation strategy in V-V ECMO for severe pneumonia: a multicenter cohort study

Zhe Li, Wan Chen, Chenglong Li, Guozheng Qiu et autres

Prognostic assessment in patients with severe pneumonia requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO) has traditionally relied on static baseline characteristics. Whether the early physiological trajectory and modifiable management strategies, specifically sedation depth, influence survival remains uncertain. We conducted a multicenter retrospective …

Early metabolic trajectory and sedation strategy in V-V ECMO for severe pneumonia: a multicenter cohort study

Zhe Li, Wan Chen, Chenglong Li, Guozheng Qiu et autres

Prognostic assessment in patients with severe pneumonia requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO) has traditionally relied on static baseline characteristics. Whether the early physiological trajectory and modifiable management strategies, specifically sedation depth, influence survival remains uncertain. We conducted a multicenter retrospective …

Early metabolic trajectory and sedation strategy in V-V ECMO for severe pneumonia: a multicenter cohort study

Zhe Li, Wan Chen, C L Li, Guozheng Qiu et autres

Background Prognostic assessment in patients with severe pneumonia requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO) has traditionally relied on static baseline characteristics. Whether the early physiological trajectory and modifiable management strategies, specifically sedation depth, influence survival remains uncertain.Methods We conducted a multicenter …

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Transcriptional profiles of skeletal muscles from 11 different anatomical locations in broiler chickens

Fanli Kong, Xinyu Wu, Bo Zeng, Lu Lu et autres

Chickens ( Gallus gallus domesticus ), one of the most abundant domesticated animals worldwide, are a major source of high-quality protein from their skeletal muscle. The growth and development of skeletal muscle directly determine the meat quality and yield in poultry. Although …

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Correlation Analysis of Hand Flexibility and Balance Function in Patients with Parkinson’s Disease

Weining Wang, Ce Li, Bo Zeng, Chen Wang et autres

INTRODUCTION: Parkinson's disease (PD) is a progressive neurological disorder caused by a reduction in dopamine in the substantia nigra and striatum of the basal ganglia. Patients with mild to moderate PD have poor hand dexterity, reduced grip strength, and lower self-perceived hand …

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Study on the microbial diversity and composition at different regions of stomach in adult pigs.

Shenqiang Hu, Zhengjiang Liu, Juan Deng, Bo Zeng et autres

was the dominant genus in the pyloric torus. Further functional analysis of stomach microbiome indicated the regions with the most active metabolic processes and cellular activity within the stomach were the esophageal groove and lesser curvature of the gastric body. These findings …

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The effects of formula milk on development, nutrient absorption, and immune characteristics of piglets

Chuang Tang, Zhengjiang Liu, Lu Lu, Bo Zeng et autres

Breast milk is widely regarded as the optimal nourishment for infants. However, due to physiological or psychosocial factors, many infants do not receive adequate breastfeeding. So, the formula milk is proposed as a substitute of breast milk, and an increasing number of …

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ASXL2 Modulates Chromatin Remodeling to Direct Osteogenesis and Multiple Cell Fate in hPDLSCs

Tianle Yang, Ying Zhou, Ruohui Han, Meilin Hu et autres

AIMS: This study investigates the epigenetic role of Additional Sex Combs-Like 2 (ASXL2) in regulating osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs), aiming to address limitations in current strategies for oral and maxillofacial tissue regeneration. METHODS: Lentiviral-mediated ASXL2 knockdown in …

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Technical innovations of signal amplification in fluorescence in situ hybridization

Jiajia Li, Jiawei Liu, Bo Zeng, Guilan Chen et autres

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A dataset of single-cell transcriptomic atlas of Bama pig and potential marker genes across seven tissues

Long Chen, Xingyan Tong, Yujie Wu, Can Liu et autres

The use of single-cell sequencing technology for single-cell transcriptomics studies in pigs is expanding progressively. However, the comprehensive classification of cell types across different anatomical tissues and organs of pig in multiple datasets remains relatively limited. This study employs single-cell and single-nucleus …

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