Aye Mya Min Aye

The right people, in the right place—assessing the impact of a new outreach model for paediatric neurology specialist services in Myanmar

Kyaw Linn, Haymar Han, Aye Mya Min Aye, Chaw Su Hlaing et autres

Background: Myanmar has a longstanding and severe shortage of paediatric neurologists, with only 11 specialists serving an estimated 14 million children, most of whom live in rural areas with limited access to tertiary care. This workforce constraint, combined with high out-of-pocket costs …

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A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity

Fahd A. Al Qureshah, Jérémie Le Pen, Nicole A. de Weerd, Marcela Moncada‐Vélez et autres

Autosomal recessive deficiency of the IFNAR1 or IFNAR2 chain of the human type I IFN receptor abolishes cellular responses to IFN-α, -β, and -ω, underlies severe viral diseases, and is globally very rare, except for IFNAR1 and IFNAR2 deficiency in Western Polynesia …

A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity

Fahd A. Al Qureshah, Jérémie Le Pen, Nicole A. de Weerd, Marcela Moncada‐Vélez et autres

Autosomal recessive deficiency of the IFNAR1 or IFNAR2 chain of the human type I IFN receptor abolishes cellular responses to IFN-α, -β, and -ω, underlies severe viral diseases, and is globally very rare, except for IFNAR1 and IFNAR2 deficiency in Western Polynesia …

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Mitigating treatment lag for infantile epileptic spasms syndrome in low‐ and middle‐income countries: Key recommendations from the South Asia allied IESS Research Group

Jitendra Kumar Sahu, Priyanka Madaan, Jithangi Wanigasinghe, Prem Chand et autres

J.H.C. has acted as an investigator for studies with GW Pharma/Jazz Pharmaceuticals, Zogenix/UCB Pharma, Vitaflo, Stoke Therapeutics, and Ultragenyx. She has been a speaker and on advisory boards for Jazz Pharmaceuticals, UCB, Biocodex, and Nutricia; all remuneration has been paid to her …

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Plasma galectin-9 relates to cognitive performance and inflammation among adolescents with vertically acquired HIV

Preeti Moar, Kyaw Linn, Thomas A. Premeaux, Scott A. Bowler et autres

OBJECTIVE: Adolescents with perinatally acquired HIV (AWH) are at an increased risk of poor cognitive development yet the underlying mechanisms remain unclear. Circulating galectin-9 (Gal-9) has been associated with increased inflammation and multimorbidity in adults with HIV despite antiretroviral therapy (ART); however, …

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Implications of the KIWE trial for low-income and lower-middle-income countries

Jitendra Kumar Sahu, Priyanka Madaan, Jithangi Wanigasinghe, Pauline Samia et autres

in, lk, Kenya (code pays fourni par la source)

Pathogen and Antibody Identification in Children with Encephalitis in Myanmar

Maria M. Galardi, Gavin M. Sowa, Cameron D. Crockett, Robert Rudock et autres

OBJECTIVE: Prospective studies of encephalitis are rare in regions where encephalitis is prevalent, such as low middle-income Southeast Asian countries. We compared the diagnostic yield of local and advanced tests in cases of pediatric encephalitis in Myanmar. METHODS: Children with suspected subacute …

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Childhood encephalitis in the Greater Mekong region (the SouthEast Asia Encephalitis Project): a multicentre prospective study

Jean‐David Pommier, Chris Gorman, Yoann Crabol, Kevin Bleakley et autres

BACKGROUND: Encephalitis is a worldwide public health issue, with a substantially high burden among children in southeast Asia. We aimed to determine the causes of encephalitis in children admitted to hospitals across the Greater Mekong region by implementing a comprehensive state-of-the-art diagnostic …

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325 Assessing the impact of blended outreach and telemedicine paediatric neurology specialist services in Myanmar

Kyaw Linn, Marcus Wootton, Aye Mya Min Aye, Chaw Su Hlaing et autres

Background Myanmar has an improving health picture with significant reductions in neonatal and paediatric mortality. However, there remain significant regional variations in specialist expertise and care. Regarding the paediatric neurology services, there are only 11 paediatric neurologists for a paediatric population of …

391 Health status of children with down syndrome in Myanmar

Khine Mi Mi Ko, Kyaw Linn, Aye Mya Min Aye, Mon Thandar Saw et autres

Background Down Syndrome children have complex healthcare needs. There was no previous data of Pediatric Down Syndrome (PDS) in Myanmar and little is known about their health status and challenges to seek proper screening tests and health care services. Since there are …

Meningococcal disease surveillance in the Asia–Pacific region (2020): The global meningococcal initiative

Aye Mya Min Aye, Xilian Bai, Ray Borrow, Sotharith Bory et autres

The degree of surveillance data and control strategies for invasive meningococcal disease (IMD) varies across the Asia-Pacific region. IMD cases are often reported throughout the region, but the disease is not notifiable in some countries, including Myanmar, Bangladesh and Malaysia. Although there …

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Etiology and clinical profiles of pediatric encephalitis in Myanmar: A prospective study (P5.158)

Alyssa E. Smith, Robert Rudock, Cameron D. Crockett, Cho Thair et autres

Identify causes and describe the clinical presentations of pediatric encephalitis.

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