Ahmed Bahieldin

Phylogenomic Characterization of SARS-CoV-2 Variants in Saudi Arabia: Insights into Viral Evolution and Transmission Dynamics

Saleh Ali Arishi, Wael A. Fathy, Mohammed Al-matary, Ahmed Bahieldin et autres

Objective: The study aimed to characterize the genomic landscape of SARS-CoV-2 variants circulating in Saudi Arabia, given the country’s critical role as a global pilgrimage destination and central hub in the Middle East, to inform public health strategies and understand regional viral …

sa (code pays fourni par la source)

Salvadora Persica’s Effects on Oral Microbiota and Possible Pathophysiological Links to Type II Diabetes Mellitus Risk Factors

Ahmed Bahieldin, Heba Jafar Sabbagh, Mohammed A. AlShehri, Abdullah M. Algarni et autres

The application of Miswak (Salvadora persica) in healthy children was investigated to identify the oral microbiota associated with risk factors for type II diabetes mellitus (T2DM). Deep sequencing of the bacterial 16S rDNA V3–V4 regions was conducted on oral microbiome samples obtained …

sa (code pays fourni par la source)

Transcriptomic Analysis Reveals the Molecular Relationship Between Common Respiratory Infections and Parkinson’s Disease

Abdulaziz O. Albeshri, Ahmed Bahieldin, Hani Mohammed Ali

Parkinson's disease (PD) is one of the most rapidly growing neurological disorders globally. The molecular relationship between common respiratory infections (RIs) and idiopathic Parkinson's disease (iPD) remains a controversial issue. Multiple studies have linked acute respiratory infections to PD, but the molecular …

sa (code pays fourni par la source)

Metagenomic Characterization of the Maerua crassifolia Soil Rhizosphere: Uncovering Microbial Networks for Nutrient Acquisition and Plant Resilience in Arid Ecosystems

Samah Al-Harbi, Nadiah Al-Sulami, Hadba Al-Amrah, Yasir Anwar et autres

Background/Objectives:Maerua crassifolia, a threatened medicinal species endemic to drylands, exhibits a pronounced drought sensitivity. Despite the critical role of microorganisms, particularly bacteria and fungi, the microbial consortia in M. crassifolia’s rhizosphere remain underexplored. Methods: Metagenomic whole genome shotgun sequencing (WGS) was employed …

sa (code pays fourni par la source)

Development of transgenic wheat plants withstand salt stress via the MDAR1 gene

Mohamed Abdelsattar, Ahmed M. Ramadan, Amin Elsadig Eltayeb, Osama M. Saleh et autres

In light of the fact that climate change has emerged as one of the difficulties confronting the global food system, researchers are obligated to work toward developing fundamental crops, particularly wheat, to combat environmental stress, including drought and salt. In the present …

Égypte, sa, jp, us (code pays fourni par la source)

Investigating the bacterial community of gray mangroves (Avicennia marina) in coastal areas of Tabuk region

Hanaa A. Ghabban, Doha A. Albalawi, Amenah Saud Alotaibi, Dikhnah Alshehri et autres

Mangrove vegetation, a threatened and unique inter-tidal ecosystem, harbours a complex and largely unexplored bacterial community crucial for nutrient cycling and the degradation of toxic pollutants in coastal areas. Despite its importance, the bacterial community composition of the gray mangrove (Avicennia marina) …

sa, Égypte (code pays fourni par la source)

Gut microbiota of children with autism spectrum disorder and healthy siblings: A comparative study

Dalia A. Abuljadayel, Asalah Alotibi, Khloud Alqothmi, Fatemah Salem Basingab et autres

genera. In conclusion, there were more pathogenic genera and species and higher levels of biomass, diversity and richness in the GM of children with ASD.

sa (code pays fourni par la source)

Identification of a novel DNA oxidative damage repair pathway, requiring the ubiquitination of the histone variant macroH2A1.1

Khalid Ouararhni, Flore Mietton, Jamal S. M. Sabir, Abdulkhaleg Ibrahim et autres

The histone variant macroH2A (mH2A), the most deviant variant, is about threefold larger than the conventional histone H2A and consists of a histone H2A-like domain fused to a large Non-Histone Region responsible for recruiting PARP-1 to chromatin. The available data suggest that …

fr, sa, bg (code pays fourni par la source)

UHRF1 poly-auto-ubiquitination induced by the anti-cancer drug, thymoquinone, is involved in the DNA repair machinery recruitment.

Naif A. R. Almalki, Jamal S. M. Sabir, Abdulkhaleg Ibrahim, Mahmoud Alhosin et autres

fr, sa (code pays fourni par la source)

Molecular detection of exosomal miRNAs of blood serum for prognosis of colorectal cancer

Tahani Bakhsh, Safiah Alhazmi, Ali Farsi, Abdulaziz Yusuf et autres

Colorectal cancer (CRC) is the third most common cancer affecting people. The discovery of new, non-invasive, specific, and sensitive molecular biomarkers for CRC may assist in the diagnosis and support therapeutic decision making. Exosomal miRNAs have been demonstrated in carcinogenesis and CRC …

sa, Égypte (code pays fourni par la source)

Influence of Gut Resistome on Humans with Autism Spectrum Disorder

Dalia A. Abuljadayel, Ahmed Bahieldin, Budur Alotaibi, Wafa M. Aresh et autres

Recent studies have shed light on the connection between the gut resistome and individuals with autism spectrum disorder (ASD). Environmental factors such as premature birth and exposure to drugs in utero can have a significant impact on children with ASD. Microorganisms present …

sa (code pays fourni par la source)

Identification and Characterization of HIRIP3 as a Histone H2A Chaperone

Maria Ignatyeva, Abdul Kareem Mohideen Patel, Abdulkhaleg Ibrahim, Raed S. Albiheyri et autres

HIRIP3 is a mammalian protein homologous to the yeast H2A.Z deposition chaperone Chz1. However, the structural basis underlying Chz's binding preference for H2A.Z over H2A, as well as the mechanism through which Chz1 modulates histone deposition or replacement, remains enigmatic. In this …

fr, sa (code pays fourni par la source)