Ahmad Rashidi

Neuron-restricted cytomegalovirus latency in the central nervous system regulated by CD4+ T-cells and IFN-γ

Fran Krstanović, Andrea Mihalić, Ahmad Rashidi, Katarzyna Sitnik et autres

All human herpesviruses establish latency following the resolution of the primary infection. Among these, α-herpesviruses HSV-1, HSV-2 and VZV establish latency in neurons, whereas neurons are not traditionally considered a site of latency for other herpesviruses. Using a combination of in vivo …

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Persistently primed microglia restrict the reactivation of latent cytomegalovirus at the expense of neuronal synaptic connectivity

Ilija Brizić, Andrea Mihalić, Daria Kveštak, Berislav Lisnić et autres

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Neuron-restricted cytomegalovirus latency in the central nervous system regulated by CD4+ T cells and IFN-γ

Ilija Brizić, Fran Krstanović, Andrea Mihalić, Ahmad Rashidi et autres

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Neurovirulence of Usutu virus in human fetal organotypic brain slice cultures partially resembles Zika and West Nile virus

Eleanor M. Marshall, Ahmad Rashidi, Michiel van Gent, Barry Rockx et autres

Usutu (USUV), West Nile (WNV), and Zika virus (ZIKV) are neurotropic arthropod-borne viruses (arboviruses) that cause severe neurological disease in humans. However, USUV-associated neurological disease is rare, suggesting a block in entry to or infection of the brain. We determined the replication, …

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Neurovirulence of Usutu virus in human fetal organotypic brain slice cultures resembles Zika and West Nile virus

Eleanor M. Marshall, Ahmad Rashidi, Michiel van Gent, Barry Rockx et autres

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Herpes simplex virus infection induces necroptosis of neurons and astrocytes in human fetal organotypic brain slice cultures

Ahmad Rashidi, Diana Nguyen Tran, Caithlin R. Peelen, Michiel van Gent et autres

BACKGROUND: Herpes simplex virus (HSV) encephalitis (HSE) is a serious and potentially life-threatening disease, affecting both adults and newborns. Progress in understanding the virus and host factors involved in neonatal HSE has been hampered by the limitations of current brain models that …

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ER stress induces caspase‐2‐tBID‐GSDME‐dependent cell death in neurons lytically infected with herpes simplex virus type 2

Fanghui Ren, Ryo Narita, Ahmad Rashidi, Stefanie Fruhwürth et autres

Neurotropic viruses, including herpes simplex virus (HSV) types 1 and 2, have the capacity to infect neurons and can cause severe diseases. This is associated with neuronal cell death, which may contribute to morbidity or even mortality if the infection is not …

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Herpes simplex virus infection induces necroptosis of neurons and astrocytes in human fetal organotypic brain slice cultures

Ahmad Rashidi, Diana Nguyen Tran, Caithlin R. Peelen, Michiel van Gent et autres

Abstract Background Herpes simplex virus (HSV) encephalitis (HSE) is a serious and potentially life-threatening disease, affecting both adults and newborns. Progress in understanding the virus and host factors involved in neonatal HSE has been hampered by the limitations of current brain models …

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Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production

Line Sinnathamby Reinert, Ahmad Rashidi, Diana Nguyen Tran, Georgios Katzilieris‐Petras et autres

Protection of the brain from viral infections involves the type I IFN (IFN-I) system, defects in which render humans susceptible to herpes simplex encephalitis (HSE). However, excessive cerebral IFN-I levels lead to pathologies, suggesting the need for tight regulation of responses. Based …

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The use of quantitative sensory testing in cancer pain assessment: A systematic review

Maisie Martland, Ahmad Rashidi, Mike Bennett, Marie Fallon et autres

OBJECTIVE: To summarize the literature on the use of quantitative sensory testing (QST) in the assessment of pain in people with cancer and to describe which QST parameters consistently demonstrate abnormal sensory processing in patients with cancer pain. DATABASES AND DATA TREATMENT: …

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Seroprevalence of Brucellosis in HIV-Infected Patients in Sanandaj, Iran

Mohammad Ali Rezaee, Ahmad Rashidi, Mohammad Ghaedi, Ali Jalili et autres

Background:: Infection with human immunodeficiency virus (HIV) leads to cellular immune deficiency and theoretically patients infected with HIV are susceptible to brucellosis. Objectives:: The current study aimed to determine brucellosis rate in the patients infected with HIV. Patients and Methods:: We included …

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Molecular Detection of Theileria Spp. and Babesia Spp. in Sheep and Ixodid Ticks

Gholam Reza Razmi, Moslem Pourhosseini, Saeed Yaghfoori, Ahmad Rashidi et autres